J Musculoskelet Neuronal Interact., 2009; 9(4): 256-62, PMID: 19949283
Age comparisons of bone density and geometry in men
Sherk VD, Karabulut M, Bemben MG, Bemben DA
Bone Density Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman Oklahoma, 73019, USA.
Abstract
Objectives: The purposes of this study were to examine tibia bone density and geometry in young and middle aged men, and to explore relationships between pQCT- and DXA-derived body composition variables. Methods: Healthy males (18-30 years old, n=31; 50-64 years old, n=37) had their total body areal bone mineral density (aBMD) and body composition measured with Dual Energy X-ray Absorptiometry (DXA). Volumetric bone characteristics, muscle cross-sectional area (MCSA) and fat cross-sectional area (FCSA) of the leg were measured with peripheral Quantitative Computed Tomography (pQCT). Results: Young men were significantly (p<0.05) lighter and had less fat mass than older men. Total volumetric BMD (vBMD) at 66% of the tibia length was significantly lower (p<0.05) in older men. Bone-free lean body mass values were useful predictors of total and cortical area and content (R(2)=0.338-0.467). MCSA was more predictive of leg BFLBM than total body BFLBM, and those relationships were stronger in older men. Conclusions: Differences in tibial bone area and density existed between young and middle-aged men, and relationships between pQCT- and DXA-derived body composition variables were age-dependent.Produktgruppen: pQCT Knochendichte & -geometrie
Themen: Klinische Studien, Klinische Anwendung, Diagnostik mit Leonardo & pQCT, Grundlagen
Doc-ID: 2086, 03.12.2009
Weitere Informationen: Original Article
