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Literatur (157)
Klinische Studien
Vitamin D status and muscle function in children with neurofibromatosis type 1 (NF1).
Objectives: The aim of this cross-sectional study was to assess the vitamin D status and muscle function in children with NF1 compared with their unaffected siblings. Methods: NF1 children between 5 and 18 year weiter...
Verfasser: Hockett CW, Eelloo J, Huson SM, Roberts SA, Berry JL, Chaloner C, Rawer R, Mughal MZ.
Quelle: J Musculoskelet Neuronal Interact., 2013; 13(1): 111-119
Doc-ID: 3152, 14.03.2013
Klinische Studien
Objectives: In order to better understand which training approaches are more effective for preventing bone loss in post-menopausal women with low bone mass, we examined the effect of a nine-month resistive exer weiter...
Verfasser: Stolzenberg N, Belavý DL, Beller G, Armbrecht G, Semler J, Felsenberg D.
Quelle: J Musculoskelet Neuronal Interact., 2013; 13(1): 66-76
Doc-ID: 3158, 14.03.2013
Klinische Studien
Mechanography is an innovative method to evaluate lower-limb dynamic muscle function. This technique is generally performed on force platforms that measure only the vertical component of ground reaction force ( weiter...
Verfasser: Veilleux LN, Rauch F, Lemay M, Ballaz L
Quelle: J Musculoskelet Neuronal Interact, 2012; 12(4): 219-23, PMID: 23196264
Doc-ID: 3073, 08.12.2012
Weitere Informationen: Original Article
Klinische Studien
Objectives: We sought to determine if a small muscle mass index (MMI) is actually detrimental for insulin sensitivity when studying a large group of postmenopausal women displaying various body composition stat weiter...
Verfasser: Lebon J, Aubertin-Leheudre M, Bobeuf F, Lord C, Labonte M, Dionne IJ
Quelle: J Musculoskelet Neuronal Interact, 2012; 12(3): 116-26, PMID: 22947543
Doc-ID: 3035, 09.09.2012
Weitere Informationen: Original Article
Klinische Studien
In this 12-month RCT, we examined whether aerobic impact exercise training (3x/week) could facilitate breast cancer survivors" recovery by enhancing their bone structural strength, physical performance and body weiter...
Verfasser: Nikander R, Sievanen H, Ojala K, Kellokumpu-Lehtinen P, Palva T, Blomqvist C, Luoto R, Saarto T
Quelle: J Musculoskelet Neuronal Interact, 2012; 12(3): 127-35, PMID: 22947544
Doc-ID: 3036, 09.09.2012
Weitere Informationen: Original Article
Klinische Studien
Impact of bed rest on conduit artery remodeling: effect of exercise countermeasures.
Physical inactivity is a potent stimulus for vascular remodeling, leading to a marked decrease in conduit artery diameter. However, little is known about the impact of physical inactivity on artery wall thickne weiter...
Verfasser: van Duijnhoven NT, Green DJ, Felsenberg D, Belavy DL, Hopman MT, Thijssen DH
Quelle: Hypertension, 2010; 56(2): 240-6, PMID: 20530294
Schlagworte: BBR
Doc-ID: 3017, 05.08.2012
Weitere Informationen: Original Article
Klinische Studien
We monitored changes in SERCA isoform specific expression and S-nitrosylation in myofibers of lower limb soleus (SOL) and vastus lateralis (VL) muscle biopsies before and after 60 days of voluntary long term b weiter...
Verfasser: Salanova M, Schiffl G, Blottner D
Quelle: Histochem Cell Biol, 2009; 132(4): 383-94, PMID: 19644701
Schlagworte: BBR1
Doc-ID: 3018, 05.08.2012
Klinische Studien
The ryanodine receptor type-I (RyR1) is one key player of the excitation-contraction coupling (E-CC) machinery. However, RyR1 expression in human skeletal muscle disuse and plasticity changes are not well docum weiter...
Verfasser: Salanova M, Schiffl G, Rittweger J, Felsenberg D, Blottner D
Quelle: Histochem Cell Biol, 2008; 130(1): 105-18, PMID: 18283481
Schlagworte: BBR
Doc-ID: 3019, 05.08.2012
Klinische Studien
The cellular mechanisms of human skeletal muscle adaptation to disuse are largely unknown. The aim of this study was to determine the morphological and biochemical changes of the lower limb soleus and vastus la weiter...
Verfasser: Salanova M, Schiffl G, Puttmann B, Schoser BG, Blottner D
Quelle: J Anat, 2008; 212(3): 306-18, PMID: 18221329
Schlagworte: BBR
Doc-ID: 3020, 05.08.2012
Weitere Informationen: Original Article
Klinische Studien
Functional assessment of the muscle-bone unit in the lower leg.
Based on the mechanostat theory and the muscle-bone hypothesis, a methodological assessment of the musculoskeletal status in health and disease should relate maximum muscle force in relation to bone mass and g weiter...
Verfasser: Anliker E, Toigo M
Quelle: J Musculoskelet Neuronal Interact, 2012; 12(2): 46-55, PMID: 22647277
Doc-ID: 2980, 05.06.2012
Weitere Informationen: Original Article
Klinische Studien
Objectives: To assess adaptations of the lower leg muscle-bone unit in 8- to 12-year-old children following a randomized controlled jumping exercise intervention for 9 months. Methods: Twelve boys and 10 girls weiter...
Verfasser: Anliker E, Dick C, Rawer R, Toigo M
Quelle: J Musculoskelet Neuronal Interact, 2012; 12(2): 56-67, PMID: 22647278
Doc-ID: 2981, 05.06.2012
Weitere Informationen: Original Article
Klinische Studien
Abnormalities in Muscle Density and Muscle Function in Hypophosphatemic Rickets.
Context:Animal studies suggest that hypophosphatemic rickets (HPR) is associated with muscle function deficits, but it is unknown whether humans with HPR have a muscle disorder.Objective:Our objective was to a weiter...
Verfasser: Veilleux LN, Cheung M, Ben Amor M, Rauch F
Quelle: J Clin Endocrinol Metab, 2012; 97(8): E1492-8, PMID: 22639288
Doc-ID: 2979, 05.06.2012
Pressestimmen
Für Ihre Forschungen besteigt Sportdoktorandin Ramona Ritzmann einen Airbus, der in rund 7000 Metern steil in die Luft steigt. Wie bewegt sich der Mensch? Wie koordiniert der Körper einen Sprung? Wie kann ein weiter...
Verfasser: Claudia Füssler
Quelle: Badische Zeitung, 2011; 04.11.: 22
Schlagworte: Parabelflüge, Universität Freiburg, DLR
Doc-ID: 2943, 10.04.2012
Klinische Studien
Short-Duration Resistive Exercise Sustains Neuromuscular Function after Bed Rest.
PURPOSE: To assess the effectiveness of a short duration, three times weekly, high-load resistive exercise program on preventing deterioration in neuromuscular function after prolonged bed rest. METHODS: Twenty weiter...
Verfasser: Gast U, John S, Runge M, Rawer R, Felsenberg D, Belavy DL
Quelle: Med Sci Sports Exerc., 2012; (44): 1764-72, PMID: 22460472
Doc-ID: 2942, 10.04.2012
Wissenschaftliche Publikationen
The dynamics of bone structure development during pubertal growth.
The pubertal growth spurt is a time of rapid changes in bone length, mass and structure, followed by the cessation of longitudinal growth. The two best studied anatomical areas in this respect are the metaphyse weiter...
Verfasser: Rauch F
Quelle: J Musculoskelet Neuronal Interact, 2012; 12(1): 1-6, PMID: 22373945
Doc-ID: 2904, 07.03.2012
Weitere Informationen: Original Article
Klinische Studien
Effect of level of farm mechanization early in life on bone later in life.
Objective: To determine whether an active rural lifestyle during childhood and adolescence, defined as low farm mechanization, was associated with bone measures later in life. Methods: DXA bone data from total weiter...
Verfasser: McCormack LA, Binkley TL, Specker BL
Quelle: J Musculoskelet Neuronal Interact, 2012; 12(1): 7-15, PMID: 22373946
Doc-ID: 2905, 07.03.2012
Weitere Informationen: Original Article
Pressestimmen
Vibrationstraining erhält Muskeln und Knochen weiter...
Quelle: Moosacher Anzeiger, 2011; 07.12.:
Schlagworte: Mars500, Weltraumforschung
Doc-ID: 2900, 21.02.2012
Pressestimmen
Gesund und Fit – Wie im Weltall, so auf Erden
"Mars500"-Mission: Erhalt von Muskeln und Knochen durch Vibrationstraining weiter...
Quelle: Infinity Magazin, 2011; 01.12.:
Schlagworte: Mars500, Weltraumforschung
Doc-ID: 2901, 21.02.2012
Wissenschaftliche Publikationen
Why bones bend but don"t break.
The musculoskeletal system is adept at dissipating potentially damaging energy that could accelerate fracture consequent to multiple loading cycles. Microstructural damage reduces bone"s residual properties, bu weiter...
Verfasser: Burr DB
Quelle: J Musculoskelet Neuronal Interact, 2011; 11(4): 270-85, PMID: 22130136
Doc-ID: 2776, 06.12.2011
Weitere Informationen: Original Article
Klinische Studien
Side-to-side differences in bone strength in master jumpers and sprinters.
Introduction: This study evaluated side-to-side difference in tibial bone structure, calf muscle cross-sectional area (CSA) and hopping force in master athletes as a result of training for sports with different weiter...
Verfasser: Ireland A, Korhonen M, Heinonen A, Suominen H, Baur C, Stevens S, Degens H, Rittweger J
Quelle: J Musculoskelet Neuronal Interact, 2011; 11(4): 298-305, PMID: 22130138
Doc-ID: 2777, 06.12.2011
Weitere Informationen: Original Article
Klinische Studien
Objective: The aim of the study was to investigate the side-to-side differences of the upper and lower limbs in chronic stroke patients by means of peripheral quantitative computed tomography (pQCT). Methods: T weiter...
Verfasser: Talla R, Galea M, Lythgo N, Angeli T, Eser P
Quelle: J Musculoskelet Neuronal Interact, 2011; 11(4): 306-13, PMID: 22130139
Doc-ID: 2778, 06.12.2011
Weitere Informationen: Original Article
Videos
Quelle: YouTube, 2010: 21.09.
Schlagworte: Mars500, Weltraumforschung
Doc-ID: 2775, 15.11.2011
Weitere Informationen: Original Article
Klinische Studien
Protein calcium sensors of the Homer family have been proposed to modulate the activity of various ion channels and nuclear factor of activated T cells (NFAT), the transcription factor modulating skeletal musc weiter...
Verfasser: Salanova M, Bortoloso E, Schiffl G, Gutsmann M, Belavy DL, Felsenberg D, Furlan S, Volpe P, Blottner D
Quelle: FASEB J, 2011; (): , PMID: 21885651
Schlagworte: BBR2
Doc-ID: 2748, 28.09.2011
Klinische Studien
BACKGROUND: bone, muscle and fat have a common progenitor, the mesenchymal stem cell preferred differentiation into adipocytes can lead to loss of bone architecture fat infiltration in bone marrow and muscle i weiter...
Verfasser: Wong AKO, Bhargava A, Beattie KA, Gordon CL, Pickard L, Webber CE, Papaioannou A, Adachi JD
Quelle: ASBMR, San Diego, 2011;
Schlagworte: Muscle Density
Doc-ID: 2743, 21.09.2011
Klinische Studien
We examined the effects of bed-rest, recovery and exercise countermeasures on bone density and structure at the distal tibia and radius as measured via high-resolution peripheral computed tomography. 24 subject weiter...
Verfasser: Belavy DL, Beller G, Ritter Z, Felsenberg D
Quelle: J Musculoskelet Neuronal Interact, 2011; 11(3): 215-26, PMID: 21885896
Schlagworte: BBR2
Doc-ID: 2729, 13.09.2011
Weitere Informationen: Original Article
Klinische Studien
12-weeks of Whole Body Vibration with Resistance Exercise is Osteogenic at the Spine
Evidence supports weight-bearing activity as a means to increase bone mineral density (BMD) and lower risk for osteoporosis. Whole body vibration (WBV) training is a novel technique that has been minimally exp weiter...
Verfasser: Almstedt HC, Urbinati CR, Ligouri GC, Spiegel M, Stapleton MR, Shoepe TC
Quelle: ACSM annual meeting, 2011;
Schlagworte: lumbar spine
Doc-ID: 2683, 26.07.2011
Klinische Studien
SUMMARY: The addition of whole-body vibration to high-load resistive exercise may provide a better stimulus for the reduction of bone loss during prolonged bed rest (spaceflight simulation) than high-load resis weiter...
Verfasser: Belavy DL, Beller G, Armbrecht G, Perschel FH, Fitzner R, Bock O, Borst H, Degner C, Gast U, Felsenberg D
Quelle: Osteoporos Int, 2011; 22(5): 1581-91, PMID: 20814665
Schlagworte: BBR2
Doc-ID: 2664, 30.06.2011
Klinische Studien
Changes in lower extremity muscle function after 56 days of bed rest.
Preservation of muscle function, known to decline in microgravity and simulation (bed rest), is important for successful spaceflight missions. Hence, there is great interest in developing interventions to prev weiter...
Verfasser: Buehring B, Belavy DL, Michaelis I, Gast U, Felsenberg D, Rittweger J
Quelle: J Appl Physiol, 2011; 111(1): 87-94, PMID: 21527664
Schlagworte: BBR1
Doc-ID: 2665, 30.06.2011
Klinische Studien
Maximum Ground Reaction Force in Relation to Tibial Bone Mass in Children and Adults.
PURPOSE:: To assess maximum voluntary forefoot ground reaction force (Fm1LH) during multiple one-legged hopping (m1LH, a new jumping maneuver) and to determine the correlation between tibial volumetric bone min weiter...
Verfasser: Anliker E, Rawer R, Boutellier U, Toigo M
Quelle: Med Sci Sports Exerc, 2011; (43): 2102-9, PMID: 21502901
Doc-ID: 2632, 19.04.2011
Klinische Studien
Background and Aim. There is limited data on the effects of inactivity (prolonged bed-rest) on parameters of endocrine and metabolic function; we therefore aimed to examine changes in these systems during and a weiter...
Verfasser: Belavy DL, Seibel MJ, Roth HJ, Armbrecht G, Rittweger J, Felsenberg D
Quelle: J Endocrinol Invest, 2012; 35(1): 54-62, PMID: 21422800
Schlagworte: BBR
Doc-ID: 2606, 07.04.2011
Klinische Studien
As part of the 2nd Berlin BedRest Study (BBR2-2), we investigated the pattern of muscle atrophy of the postero-lateral hip and hamstring musculature during prolonged inactivity and the effectiveness of two exer weiter...
Verfasser: Miokovic T, Armbrecht G, Felsenberg D, Belavy DL
Quelle: J Appl Physiol., 2011; 110(4: :926-34., PMID: 21233337
Schlagworte: BBR2
Doc-ID: 2612, 07.04.2011
Klinische Studien
OBJECTIVE: : Whole body vibration is a potential therapy for age-related loss of musculoskeletal competence. Vibration has improved bone in animal models, but evidence in humans is limited. Relative efficacy weiter...
Verfasser: Beck BR, Norling TL
Quelle: Am J Phys Med Rehabil., 2010; 89(12): 997-1009, PMID: 21403595
Doc-ID: 2607, 07.04.2011
Wissenschaftliche Publikationen
What do we currently know from in vivo bone strain measurements in humans
Bone strains are the most important factors for osteogenic adaptive responses. During the past decades, scientists have been trying to describe the relationship between bone strain and bone osteogenic responses weiter...
Verfasser: Yang PF, Brüggemann GP, Rittweger J
Quelle: J Musculoskelet Neuronal Interact., 2011; 11(1): 8-20, PMID: 21364270
Doc-ID: 2584, 05.03.2011
Weitere Informationen: Original Article
Grundlagenstudien
Analyses of muscular mass and function: the impact on bone mineral density and peak muscle mass
Bone density and bone mass are commonly regarded as the essential parameters to describe fracture risk in osteology. Because fractures primarily depend on bone strength and secondarily on bone mass and density, weiter...
Verfasser: Fricke O, Beccard R, Semler O, Schoenau E
Quelle: Pediatr Nephrol., 2010; 25(12): 2393-400, PMID: 20458595
Doc-ID: 2571, 22.02.2011
Klinische Studien
BACKGROUND/AIMS: Because the increasing fracture incidence has not been understood, the present study compares variables of the muscle-bone interaction to examine the hypothesis that an impaired adaptation of weiter...
Verfasser: Beccard R, Land C, Semler O, Fricke O, Remer T, Stabrey A, Schoenau E
Quelle: Horm Res Paediatr., 2010; 74(5): 312-8, PMID: 20395668
Doc-ID: 2572, 22.02.2011
Klinische Studien
To evaluate the effect of short-duration, high-load resistive exercise, with and without whole body vibration on lumbar muscle size, intervertebral disk and spinal morphology changes, and low back pain (LBP) in weiter...
Verfasser: Belavý DL, Armbrecht G, Gast U, Richardson CA, Hides JA, Felsenberg D
Quelle: J Appl Physiol., 2010; 109(6): 1801-11, PMID: 20864564
Doc-ID: 2509, 13.01.2011
Klinische Studien
Neuromuscular performance and bone structural characteristics in young healthy men and women
Muscle mass and strength have been shown to be important factors in bone strength. Low muscular force predisposes to falling especially among elderly. Regular exercise helps to prevent falls and resulting bone weiter...
Verfasser: Rantalainen T, Heinonen A, Komi PV, Linnamo V
Quelle: Eur J Appl Physiol., 2008; 102(2): 215-22, PMID: 17926061
Doc-ID: 2450, 28.10.2010
Klinische Studien
The 2(nd) Berlin BedRest Study: protocol and implementation
Long-term bed-rest is used to simulate the effect of spaceflight on the human body and test different kinds of countermeasures. The 2nd Berlin BedRest Study (BBR2-2) tested the efficacy of whole-body vibration weiter...
Verfasser: Belavy DL, Bock O, Börst H, Armbrecht G, Gast U, Degner C, Beller G, Soll H, Salanova M, Habazettl H, Heer M, de Haan A, Stegeman DF, Cerretelli P, Blottner D, Rittweger J, Gelfi C, Kornak U, Felsenberg D
Quelle: J Musculoskelet Neuronal Interact., 2010; 10(3): 207-19, PMID: 20811145
Doc-ID: 2394, 03.09.2010
Weitere Informationen: Original Article
Klinische Studien
Spinal cord injury (SCI), as a primarily neurological disorder that causes muscular atrophy, is well known to be associated with sub-lesional bone losses. These losses are more pronounced from epiphyseal than f weiter...
Verfasser: Rittweger J, Goosey-Tolfrey VL, Cointry G, Ferretti JL
Quelle: Bone, 2010; 47(3): 511-8, PMID: 20561989
Doc-ID: 2336, 14.07.2010
Klinische Studien
Objectives: We sought to identify the variance in radius bone strength indices explained by forearm muscle cross sectional area (MCSA) and isometric (ISO), concentric (CON), or eccentric (ECC) grip torque in he weiter...
Verfasser: Frank AW, Lorbergs AL, Chilibeck PD, Farthing JP, Kontulainen SA
Quelle: J Musculoskelet Neuronal Interact., 2010; 10(2): 136-41, PMID: 20516630
Doc-ID: 2290, 07.06.2010
Weitere Informationen: Original Article
Grundlagenstudien
Biological underpinnings of Frost"s mechanostat thresholds: The important role of osteocytes
Harold Frost first proposed the existence of several mechanical thresholds in bone, two of which determine whether bone is added to, or lost from, the skeleton. Recent evidence from bone biology helps elucidate weiter...
Verfasser: Hughes JM, Petit MA
Quelle: J Musculoskelet Neuronal Interact., 2010; 10(2): 128-35, PMID: 20516629
Doc-ID: 2293, 07.06.2010
Weitere Informationen: Original Article
Klinische Studien
Vibration as an exercise modality: how it may work, and what its potential might be
Whilst exposure to vibration is traditionally regarded as perilous, recent research has focussed on potential benefits. Here, the physical principles of forced oscillations are discussed in relation to vibratio weiter...
Verfasser: Rittweger J
Quelle: Eur J Appl Physiol., 2010; 108(5): 877-904, PMID: 20012646
Doc-ID: 2284, 24.05.2010
Klinische Studien
During and after prolonged bed rest, changes in bone metabolic markers occur within 3 days. Resistive vibration exercise during bed rest impedes bone loss and restricts increases in bone resorption markers whil weiter...
Verfasser: Armbrecht G, Belavý DL, Gast U, Bongrazio M, Touby F, Beller G, Roth HJ, Perschel FH, Rittweger J, Felsenberg D
Quelle: Osteoporos Int., 2010; 21(4): 597-607, PMID: 19536451
Schlagworte: BBR
Doc-ID: 2288, 24.05.2010
Klinische Studien
Bed rest is a recognized model for muscle atrophy and bone loss in space flight and in clinical medicine. We hypothesized that whole body vibration in combination with resistive exercise (RVE) would be an effec weiter...
Verfasser: Rittweger J, Beller G, Armbrecht G, Mulder E, Buehring B, Gast U, Dimeo F, Schubert H, de Haan A, Stegeman DF, Schiessl H, Felsenberg D
Quelle: Bone, 2010; 46(1): 137-47, PMID: 19732856
Schlagworte: BBR2
Doc-ID: 2285, 24.05.2010
Klinische Studien
EMG activity during whole body vibration: motion artifacts or stretch reflexes
The validity of electromyographic (EMG) data recorded during whole body vibration (WBV) is controversial. Some authors ascribed a major part of the EMG signal to vibration-induced motion artifacts while others weiter...
Verfasser: Ritzmann R, Kramer A, Gruber M, Gollhofer A, Taube W
Quelle: Eur J Appl Physiol., 2010; 110(1): 143-51, PMID: 20419311
Schlagworte: Strech Reflex
Doc-ID: 2242, 28.04.2010
Klinische Studien
Age-Related Changes in Physical Function in Community-Dwelling People Aged 50-79 Years
[Purpose] We aimed to obtain the mean values for physical function tests in healthy community-dwelling people aged 50-79 years and to compare these values between age decades. [Subjects and Methods] We recr weiter...
Verfasser: Tsubaki A, Kubo M, Kobayashi R, Jigami H, Takahashi HE
Quelle: J. Phys. Ther. Sci, 2010; 22/1: 23-27
Doc-ID: 2231, 09.04.2010
Weitere Informationen: Original Article
Klinische Studien
Non-invasive (pQCT) biomechanical analysis of the whole human tibia in normal men and women
Verfasser: Feldman S, Capozza R, Mortario P, Yelin I, Reina P, Schiessl H, Rittweger J, Ferretti JL, Cointry GR
Quelle: ASBMR, 2009;
Doc-ID: 2228, 09.04.2010
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Klinische Studien
Structural and biomechanical analysis of the whole tibia by pQCT in trained long-distance runners
Verfasser: Feldman S, Capozza R, Mortarino P. Yelin I, Reina P, Ullna MR, Rittweger J, Ferretti JL, Cointry GR
Quelle: ASBMR, 2009;
Doc-ID: 2229, 09.04.2010
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Klinische Studien
Verfasser: Feldman S, Capozza RF, Cointry GR, Ferretti SE, Reina PS, Homse B, Zapata M, Mansur JL, Ferretti JL
Quelle: ASBMR, 2007;
Doc-ID: 2224, 09.04.2010
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Klinische Studien
Trabecular bone mass evaluation as related to cortical mass in the human leg. A pQCT study.
Verfasser: Cointry GR, Capozza RF, Feldman S, Mortarino P, Maffei L, Alvarisqueta A, Ferretti JL
Quelle: ASBMR, 2007;
Doc-ID: 2227, 09.04.2010
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Klinische Studien
Verfasser: Capozza R, Reina P, Cointry G, Feldman S, Castellini S, Rittweger J, Ferretti JL
Quelle: ASBMR, 2007;
Doc-ID: 2226, 09.04.2010
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Klinische Studien
Structural analysis of the human tibia by tomographic (pQCT) serial scans
Abstract This study analyses the evaluation of tomographic indicators of tibia structure, assuming that the usual loading pattern shifts from uniaxial compression close to the heel to a combined compression, to weiter...
Verfasser: Capozza RF, Feldman S, Mortarino P, Reina PS, Schiessl H, Rittweger J, Ferretti JL, Cointry GR
Quelle: J Anat., 2010; 216: 470 -481, PMID: 20136670
Doc-ID: 2194, 23.03.2010
Klinische Studien
Skeletal geometry and indices of bone strength in artistic gymnasts
This review addresses bone geometry and indices of skeletal strength associated with exposure to gymnastic loading during growth. A brief background characterizes artistic gymnastics as a mechanical loading mod weiter...
Verfasser: Dowthwaite JN, Scerpella TA
Quelle: J Musculoskelet Neuronal Interact., 2009; 9(4): 198-214, PMID: 19949278
Doc-ID: 2109, 18.12.2009
Weitere Informationen: Original Article
Klinische Studien
Acute whole-body vibration elicits post-activation potentiation
Whole-body vibration (WBV) leads to a rapid increase in intra-muscular temperature and enhances muscle power. The power-enhancing effects by WBV can, at least in part, be explained by intra-muscular temperature weiter...
Verfasser: Cochrane DJ, Stannard SR, Firth EC, Rittweger J
Quelle: Eur J Appl Physiol., 2009; PMID: 19795130
Schlagworte: BBR2
Doc-ID: 2098, 07.12.2009
Klinische Studien
Resistive vibration exercise reduces lower limb muscle atrophy during 56-day bed-rest
Objectives: The current study aimed to examine the effectiveness of a resistive vibration exercise countermeasure during prolonged bed-rest in preventing lower-limb muscle atrophy. Methods: 20 male subjects und weiter...
Verfasser: Belavý DL, Miokovic T, Armbrecht G, Rittweger J, Felsenberg D
Quelle: J Musculoskelet Neuronal Interact., 2009; 9(4): 225-35, PMID: 19949280
Schlagworte: BBR, Galileo Space
Doc-ID: 2083, 03.12.2009
Weitere Informationen: Original Article
Klinische Studien
Objectives: To compare the skeletal benefits associated with gymnastics between ulna and radius. Methods: 19 retired artistic gymnasts, aged 18-36 years, were compared to 24 sedentary women. Bone mineral conten weiter...
Verfasser: Ducher G, Hill BL, Angeli T, Bass SL, Eser P
Quelle: J Musculoskelet Neuronal Interact., 2009; 9(4): 247-55, PMID: 19949282
Doc-ID: 2085, 03.12.2009
Weitere Informationen: Original Article
Klinische Studien
Objective: To investigate whether athletic participation allows master athletes to preserve their good bone health into old age. Methods: Bone strength indicators of the tibia and the radius were obtained of ma weiter...
Verfasser: Wilks DC, Winwood K, Gilliver SF, Kwiet A, Sun LW, Gutwasser C, Ferretti JL, Sargeant AJ, Felsenberg D, Rittweger J
Quelle: J Musculoskelet Neuronal Interact., 2009; 9(4): 236-46, PMID: 19949281
Schlagworte: Master Athletes
Doc-ID: 2084, 03.12.2009
Weitere Informationen: Original Article
Klinische Studien
Objectives: To determine the relationship between maximum power relative to body weight (Pmax-rel) and the aging process, and to indicate the target values of improvement of motor function in Japanese individua weiter...
Verfasser: Tsubaki A, Kubo M, Kobayashi R, Jigami H, Takahashi HE
Quelle: J Musculoskelet Neuronal Interact., 2009; 9(4): 263-7, PMID: 19949284
Schlagworte: Leonardo Normative Data
Doc-ID: 2082, 02.12.2009
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
The role of changes in mechanical usage set points in the pathogenesis of osteoporosis
Mechanical usage (MU) effects on modeling drifts and BMU-based remodeling affect bone mass in defined ways. Decreased MU stops additions of bone by modeling and increases removal of bone next to marrow by remod weiter...
Verfasser: Frost HM
Quelle: J Bone Miner Res., 1992; 7(3): 253-61, PMID: 1585826
Doc-ID: 2077, 25.11.2009
Klinische Studien
Examining the developing skeletal muscle: Why, what and how
This review focuses on methodological concepts in the evaluation of skeletal muscle function, taking into account classical muscle physiology, the developing motor system in children and anthropometric paramete weiter...
Verfasser: Fricke O, Schoenau E
Quelle: J Musculoskelet Neuronal Interact., 2005; 5(3): 225-31, PMID: 16172513
Doc-ID: 2074, 25.11.2009
Weitere Informationen: Original Article
Klinische Studien
The present text deals with the relationship of muscle force and mass to bone mass and geometry in the developing skeleton of children and adolescents. Recent results of the last ten years are discussed with re weiter...
Verfasser: Fricke O, Schoenau E
Quelle: Growth Horm IGF Res., 2007; 17(1): 1-9, PMID: 17194607
Doc-ID: 2076, 25.11.2009
Wissenschaftliche Publikationen
Verfasser: Frost HM, Ferretti JL, Jee WS
Quelle: Calcif Tissue Int., 1998; 62(1): 1-7, PMID: 9405724
Doc-ID: 2079, 25.11.2009
Wissenschaftliche Publikationen
Skeletal adaptations during growth
NASA: The authors examine the role of mechanical usage in skeletal development. Principle mechanisms of bone physiology include longitudinal bone growth; modeling drifts; micromodeling; remodeling by the basic weiter...
Verfasser: Jee WS, Frost HM
Quelle: Triangle., 1992; 31(2/3): 77-88, PMID: 11539347
Doc-ID: 2078, 25.11.2009
Pressestimmen
Zehn Minuten Training am Tag halten Astronauten fit
Der Mars scheint für uns Erdbewohner schier unerreichbar weit entfernt zu liegen. Aber dieser Eindruck täuscht möglicherweise: Durch die Resultate der "Berliner Bedrest-Studie", die gestern in einer Presseko weiter...
Verfasser: Shafy S
Quelle: Die Welt Online, 2004;
Doc-ID: 1966, 28.09.2009
Weitere Informationen: Original Article
Pressestimmen
1440 Stunden Bettruhe für eine Mars-Mission
Als "Erdastronaut" auf dem Steglitzer Campus Benjamin Franklin: Sechs Männer, ein Charité-Experiment - und ein großer Traum weiter...
Verfasser: Kotlorz T
Quelle: Die Welt Online, 2008;
Doc-ID: 1958, 28.09.2009
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
Biomechanical loading of Achilles tendon during normal locomotion
Direct in vivo Achilles tendon force measurements open up new possibilities for understanding the loading of the Achilles tendon during natural locomotion. This article describes how these human experiments can weiter...
Verfasser: Komi PV, Fukashiro S, Järvinen M
Quelle: Clin Sports Med., 1992; 11(3): 521-31, PMID: 1638639
Doc-ID: 1879, 04.08.2009
Wissenschaftliche Publikationen
In vivo measurement-based estimations of the human Achilles tendon moment arm
The aim of the present study was to estimate and compare in vivo measurement-based Achilles tendon moment arm lengths at rest and during isometric plantarflexion maximum voluntary contraction (MVC) using the ce weiter...
Verfasser: Maganaris CN, Baltzopoulos V, Sargeant AJ
Quelle: Eur J Appl Physiol., 2000; 83(4 -5): 363-9, PMID: 11138576
Schlagworte: maximum internal forces on tibia
Doc-ID: 1876, 04.08.2009
Wissenschaftliche Publikationen
BACKGROUND/AIMS: The present analyses intend to clarify if gender and puberty modify the relationship between bone development (modeling and remodeling) and fat mass at the forearm. METHODS: Data were collected weiter...
Verfasser: Fricke O, Sumnik Z, Tutlewski B, Stabrey A, Remer T, Schoenau E
Quelle: Horm Res., 2008; 70(2): 105-11, PMID: 18547958
Doc-ID: 1857, 28.07.2009
Wissenschaftliche Publikationen
BACKGROUND: Several reports give evidence that the perichondral ossificiation of bone tubes (modeling) strongly depends on muscular forces in children and adolescents. The present analyses intend to investigate weiter...
Verfasser: Fricke O, Beccard R, Semler O, Land C, Stabrey A, Tutlewski B, Remer T, Schoenau E
Quelle: Horm Res., 2008; 70(5): 285-93, PMID: 18824867
Doc-ID: 1855, 28.07.2009
Wissenschaftliche Publikationen
Mechanical influences on bone development in children
This review focuses on methodological concepts in the evaluation of skeletal muscle function and on adaptation. It is now thought that the critical property of bone is strength rather than weight, and that cont weiter...
Verfasser: Schoenau E, Fricke O
Quelle: Eur J Endocrinol., 2008; 159 Suppl 1: S27-31, PMID: 18787052
Doc-ID: 1856, 28.07.2009
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
What is new in neuro-musculoskeletal interactions: mechanotransduction, microdamage and repair
Verfasser: Rittweger J
Quelle: J Musculoskelet Neuronal Interact., 2007; 7(2): 191-3, PMID: 17627090
Doc-ID: 1847, 27.07.2009
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
What is new in neuro-musculoskeletal interactions: Strain on Bones
Verfasser: Rauch F, Rittweger J
Quelle: J Musculoskelet Neuronal Interact., 2002; 2(5): 489-92, PMID: 15758418
Doc-ID: 1849, 27.07.2009
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
What is new in neuro-musculoskeletal interactions: Bye-bye, density?
Verfasser: Rauch F
Quelle: J Musculoskelet Neuronal Interact., 2003; 3(3): 258-60, PMID: 15758350
Doc-ID: 1851, 27.07.2009
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
What is new in neuro-musculoskeletal interactions: Research with impact
Verfasser: Rauch F, Rittweger J
Quelle: J Musculoskelet Neuronal Interact., 2001; 1(4): 393-8, PMID: 15758490
Doc-ID: 1848, 27.07.2009
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
What is new in neuro-musculoskeletal interactions: On soups, hips and humeri
Verfasser: Rittweger J, Rauch F
Quelle: J Musculoskelet Neuronal Interact., 2003; 3(1): 101-4, PMID: 15758372
Doc-ID: 1850, 27.07.2009
Weitere Informationen: Original Article
Klinische Studien
Muscle performance, body composition and bone mass at the lumbar spine and proximal femur with DXA, structural traits at the tibia and radius with pQCT, and biomarkers of bone metabolism were assessed at baseli weiter...
Verfasser: Uusi-Rasi K, Sievanen H, Kannus P, Pasanen M, Kukkonen-Harjula K, Fogelholm M.
Quelle: J Musculoskelet Neuronal Interact., 2009; 9(2):72-80: , PMID: 19516082
Doc-ID: 1836, 21.07.2009
Weitere Informationen: Original Article
Klinische Studien
Long-Term Leisure Time Physical Activity and Properties of Bone: A Twin Study
Abstract Effects of physical activity on bone properties when controlled for genetic effects are not fully understood. We aimed to investigate association between long-term leisure time physical activity (LTPA) weiter...
Verfasser: Ma H, Leskinen T, Alen M, Cheng S, Sipilä S, Heinonen A, Kaprio J, Suominen H, Kujala UM
Quelle: J Bone Miner Res., 2009; 24/8: 1427-33, PMID: 19335223
Doc-ID: 1801, 16.04.2009
Klinische Studien
Muscle indices do not fully account for enhanced upper extremity bone mass and strength in gymnasts
OBJECTIVES: Muscular forces are an important determinant of bone strength, but bone may also adapt to non-muscular loading. We tested the hypothesis that loads associated with childhood gymnastics yield high ar weiter...
Verfasser: Dowthwaite JN, Kanaley JA, Spadaro JA, Hickman RM, Scerpella TA
Quelle: J Musculoskelet Neuronal Interact., 2009; 9(1): 2-14, PMID: 19240362
Doc-ID: 1797, 15.04.2009
Weitere Informationen: Original Article
Klinische Studien
Recovery of muscle atrophy and bone loss from 90 days bed rest: results from a one-year follow-up
Earlier studies found the recovery of bone loss after clinical immobilization to be incomplete. It has been argued that this is due to the human skeleton"s inability to accrue bone mass once peak bone mass has weiter...
Verfasser: Rittweger J, Felsenberg D
Quelle: Bone., 2009; 44(2): 214-24, PMID: 19022418
Schlagworte: BedRest
Doc-ID: 1734, 16.03.2009
Grundlagenstudien
OBJECTIVE: This study was designed to evaluate the postimpact response of the articular cartilage in the rabbit knee after a single traumatic episode. DESIGN: A novel servo-controlled Rabbit Impact Test System weiter...
Verfasser: Milentijevic D, Rubel IF, Liew AS, Helfet DL, Torzilli PA
Quelle: J Orthop Trauma., 2005; 19(7): 466-73, PMID: 16056079
Doc-ID: 1700, 21.01.2009
Klinische Studien
Our primary objective was to validate the Bone Strength Index for compression (BSIC) by determining the amount of variance in failure load and stiffness that was explained by BSIC and bone properties at two dis weiter...
Verfasser: Kontulainen SA, Johnston JD, Liu D, Leung C, Oxland TR, McKay HA
Quelle: J Musculoskelet Neuronal Interact., 2008; 8(4): 401-9, PMID: 19147978
Schlagworte: pQCT, Strength Indices, Failure Load, Stiffness, Moment, Flexural Rigidity tibia, strength index
Doc-ID: 1691, 21.01.2009
Weitere Informationen: Original Article
Klinische Studien
The aim of this contribution is to provide reference data for peripheral quantitative computed tomography (Stratec XCT2000(R)) performed at the proximal radius (the so-called "65% site") of young subjects and t weiter...
Verfasser: Rauch F, Schoenau E
Quelle: J Musculoskelet Neuronal Interact., 2008; 8(3): 217-26, PMID: 18799854
Schlagworte: Bone Geometry, Bone Mineral Density, Bone Size, Children, Peripheral Quantitative Computed Tomography
Doc-ID: 1689, 21.01.2009
Weitere Informationen: Original Article
Klinische Studien
Asymmetric bone adaptations to soleus mechanical loading after spinal cord injury
The purpose of this report is to examine longitudinal bone mineral density (BMD) changes in individuals with spinal cord injury (SCI) who began unilateral soleus electrical stimulation early after injury. Twelv weiter...
Verfasser: Dudley-Javoroski S, Shields RK
Quelle: J Musculoskelet Neuronal Interact., 2008; 8(3): 227-38, PMID: 18799855
Schlagworte: Spinal chord injury, bone adaptation, Peripheral Quantitative Computed Tomography, Electrical Stimulation, Compression, Tension
Doc-ID: 1697, 21.01.2009
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
Ten years muscle-bone hypothesis: What have we learned so far? -Almost a Festschrift-
The importance of mechanical stimuli for bone is widely appreciated. Mechanostat theory proposes a negative feedback system to explain the adaptation of bone by homeostatic control of peak strains. However, no weiter...
Verfasser: Rittweger J
Quelle: J Musculoskelet Neuronal Interact., 2008; 8(2): 174-8, PMID: 18622086
Doc-ID: 1650, 28.11.2008
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
The Utah Paradigm of Skeletal Physiology with its key component, the mechanostat hypothesis, suggest plausible explanations of some of the tissue-level changes occurring from combining selected non-mechanical a weiter...
Verfasser: Jee WS, Tian XY
Quelle: J Musculoskelet Neuronal Interact., 2005; 5(2): 110-8, PMID: 15951626
Doc-ID: 1641, 20.11.2008
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
Musculoskeletal responses of 2-year-old Thoroughbred horses to early training. Conclusions
This paper summarises and presents in context the main findings of an extensive series of studies of early training lasting 13 weeks in which the tissue responses of 2-year-old Thoroughbred horses were assessed weiter...
Verfasser: Firth EC, Rogers CW
Quelle: N Z Vet J., 2005; 53(6): 377-83, PMID: 16317437
Doc-ID: 1620, 19.11.2008
Klinische Studien
The fracture of bone plays a key role in osteoporosis. BMD measurement, however, is only an indirect parameter of this phenomenon. We therefore developed a highly sensitive three-point bending test for the meta weiter...
Verfasser: Stürmer EK, Seidlová-Wuttke D, Sehmisch S, Rack T, Wille J, Frosch KH, Wuttke W, Stürmer KM
Quelle: J Bone Miner Res., 2006; 21(1): 89-96, PMID: 16355277
Doc-ID: 1638, 19.11.2008
Grundlagenstudien
In vivo human tendon mechanical properties: effect of resistance training in old age
Recent advances in ultrasound scanning have made it possible to obtain the mechanical properties of human tendons in vivo. Application of the in vivo method in elderly individuals showed that their patellar ten weiter...
Verfasser: Maganaris CN, Narici MV, Reeves ND
Quelle: J Musculoskelet Neuronal Interact., 2004; 4(2): 204-8, PMID: 15615128
Doc-ID: 1633, 19.11.2008
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
Bone growth in length and width: the Yin and Yang of bone stability
Bone growth in length is primarily achieved through the action of chondrocytes in the proliferative and hypertrophic zones of the growth plate. Longitudinal growth is controlled by systemic, local paracrine and weiter...
Verfasser: Rauch F
Quelle: J Musculoskelet Neuronal Interact., 2005; 5(3): 194-201, PMID: 16172510
Doc-ID: 1586, 19.11.2008
Weitere Informationen: Original Article
Grundlagenstudien
Adaptation of the tendon to mechanical usage
Tendons primarily function as contractile force transmitters, but their mechanical properties may change dependent upon their level of mechanical usage. Using an ultrasound-based technique we have assessed tend weiter...
Verfasser: Reeves ND
Quelle: J Musculoskelet Neuronal Interact., 2006; 6(2): 174-80, PMID: 16849829
Doc-ID: 1632, 19.11.2008
Weitere Informationen: Original Article
Klinische Studien
Spinal cord injury (SCI) is associated with a marked and rapid sublesional bone loss. So far, reports about the time course of adaptive changes in bone mass and structure in people with chronic and complete SCI weiter...
Verfasser: Frotzler A, Berger M, Knecht H, Eser P
Quelle: Bone., 2008; 43(3): 549-55, PMID: 18567554
Schlagworte: spinal chord injury bone strength
Doc-ID: 1577, 11.11.2008
Klinische Studien
Mechanographic characteristics of adolescents and young adults with congenital heart disease
The present study comprised 29 adolescents and young adults (15 females, 14 males; aged 14.1-23.9 years) with congenital heart disease (CHD) and focused on the interaction between the biomechanical system and C weiter...
Verfasser: Fricke O, Witzel C, Schickendantz S, Sreeram N, Brockmeier K, Schoenau E
Quelle: Eur J Pediatr., 2008; 167(3): 331-6, PMID: 17516086
Doc-ID: 1559, 06.11.2008
Wissenschaftliche Publikationen
Verfasser: Sievänen H, Kannus P, Järvinen TL
Quelle: PLoS Med., 2007; 4(3): e27, PMID: 17341126
Doc-ID: 1517, 09.09.2008
Weitere Informationen: Original Article
Klinische Studien
Whole body vibration in cystic fibrosis - a pilot study
Introduction: In cystic fibrosis (CF), bone mass deficits as well as a lack of muscle mass and force have been described. The bone mass deficits are thought to be at least in part secondary to the reduced muscl weiter...
Verfasser: Roth J, Wust M, Rawer R, Schnabel D, Armbrecht G, Beller G, Rembitzki I, Wahn U, Felsenberg D, Staab D
Quelle: J Musculoskelet Neuronal Interact., 2008; 8(2): 179-87, PMID: 18622087
Schlagworte: Cystic Fibrosis, Whole Body Vibration, Bone, Muscle, Osteoporosis
Doc-ID: 1382, 22.07.2008
Weitere Informationen: Original Article
Grundlagenstudien
Vibrational loading can stimulate the formation of new trabecular bone or maintain bone mass. Studies investigating vibrational loading have often used whole-body vibration (WBV) as their loading method. Howeve weiter...
Verfasser: Christiansen BA, Bayly PV, Silva MJ
Quelle: J Biomech Eng., 2008; 130(4): 044502, PMID: 18601464
Doc-ID: 1366, 11.07.2008
Wissenschaftliche Publikationen
Relative strength of the tibia and fibula and locomotor behavior in hominoids
The fibula has rarely been considered in comparative morphological studies, probably due to its relatively minor role in carrying mechanical loads. However, some differences in morphology (and inferred function weiter...
Verfasser: Marchi D
Quelle: J Hum Evol., 2007; 53(6): 647-55, PMID: 17675139
Doc-ID: 1331, 19.06.2008
Klinische Studien
This observational study analyzes Ca-P metabolism and its impact on bone mass accrual and density and the muscle-bone mass/mass relationships in male and female children and adolescents who were parathyroidecto weiter...
Verfasser: Schneider P, Biko J, Reiners C, Demidchik YE, Drozd VM, Capozza RF, Cointry GR, Ferretti JL
Quelle: Exp Clin Endocrinol Diabetes., 2004; 112(8): 444-50, PMID: 15372365
Schlagworte: TBMC vs. TLM
Doc-ID: 1291, 21.03.2008
Klinische Studien
This 16-month randomized, controlled school-based study compared change in tibial bone strength between 281 boys and girls participating in a daily program of physical activity (Action Schools! BC) and 129 same weiter...
Verfasser: Macdonald HM, Kontulainen SA, Khan KM, McKay HA
Quelle: J Bone Miner Res., 2007; 22(3): 434-46, PMID: 17181400
Doc-ID: 1253, 06.03.2008
Klinische Studien
Quantifying leisure physical activity and its relation to bone density and strength
PURPOSE: Compare three published methods of quantifying physical activity (total activity, peak strain, and bone-loading exposure (BLE) scores) and identify their associations with areal bone mineral density (a weiter...
Verfasser: Shedd KM, Hanson KB, Alekel DL, Schiferl DJ, Hanson LN, Van Loan MD
Quelle: Med Sci Sports Exerc., 2007; 39(12): 2189-98, PMID: 18046190
Doc-ID: 1277, 06.03.2008
Wissenschaftliche Publikationen
Bone mineral density in chimpanzees, humans, and Japanese macaques
We performed a comparative study of bone mechanical properties in the radii of chimpanzees (Pan troglodytes), humans (Homo sapiens), and Japanese macaques (Macaca fuscata) using peripheral quantitative computed weiter...
Verfasser: Kikuchi Y, Udono T, Hamada Y
Quelle: Primates., 2003; 44(2): 151-5, PMID: 12687479
Doc-ID: 1257, 06.03.2008
Klinische Studien
In this large population-based study in young men, we show that the COMT val158met polymorphism modulates the association between physical activity, aBMD (DXA), and trabecular vBMD (pQCT). INTRODUCTION: Peak BM weiter...
Verfasser: Lorentzon M, Eriksson AL, Nilsson S, Mellström D, Ohlsson C
Quelle: J Bone Miner Res., 2007; 22(8): 1165-72, PMID: 17451372
Doc-ID: 1274, 06.03.2008
Klinische Studien
This perspective paper presents a hypothesis that links abnormalities of bone material with densitometric findings in two congenital metabolic bone disorders, osteogenesis imperfecta type I (OI) and X-linked hy weiter...
Verfasser: Rauch F
Quelle: J Musculoskelet Neuronal Interact., 2006; 6(2): 142-6, PMID: 16849823
Doc-ID: 1261, 06.03.2008
Weitere Informationen: Original Article
Klinische Studien
Bone density and hemoglobin levels in older persons: results from the InCHIANTI study
Hypoxemia has been recognized as a risk factor for bone loss. The aim of the present study is to investigate the relationship of bone mass and density measures with anemia and hemoglobin levels in a large sampl weiter...
Verfasser: Cesari M, Pahor M, Lauretani F, Penninx BW, Bartali B, Russo R, Cherubini A, Woodman R, Bandinelli S, Guralnik JM, Ferrucci L
Quelle: Osteoporos Int., 2005; 16(6): 691-9, PMID: 15455197
Doc-ID: 1236, 05.03.2008
Wissenschaftliche Publikationen
Measurement of bone density and bone strength with pQCT
Verfasser: J. Willnecker
Quelle: Novel approaches towards primate toxicology, 2006; 13 - 19
Doc-ID: 1213, 05.03.2008
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Klinische Studien
Bone adaptation to altered loading after spinal cord injury: a study of bone and muscle strength
Bone loss from the paralysed limbs after spinal cord injury (SCI) is well documented. Under physiological conditions, bones are adapted to forces which mainly emerge from muscle pull. After spinal cord injury ( weiter...
Verfasser: Rittweger J, Gerrits K, Altenburg T, Reeves N, Maganaris CN, de Haan A
Quelle: J Musculoskelet Neuronal Interact., 2006; 6(3): 269-76, PMID: 17142949
Doc-ID: 1207, 05.03.2008
Weitere Informationen: Original Article
Klinische Studien
Determinants of bone mass and bone size in a large cohort of physically active young adult men
The determinants of bone mineral density (BMD) at multiple sites were examined in a fit college population. Subjects were 755 males (mean age = 18.7 years) entering the United States Military Academy. A questio weiter...
Verfasser: Ruffing JA, Cosman F, Zion M, Tendy S, Garrett P, Lindsay R, Nieves JW
Quelle: Nutr Metab (Lond)., 2006; 3: 14, PMID: 16480509
Doc-ID: 1219, 05.03.2008
Weitere Informationen: Original Article
Klinische Studien
Muskel und Knochen - eine funktionelle Einheit
Einleitung: Im sich entwickelnden Organismus von Kindern und Jugendlichen steht die Kraft und die Masse der Muskulatur in biologischer Beziehung zur Geometrie und Masse des Skeletts. Methoden: Vor dem Hintergr weiter...
Verfasser: E Schönau, O Fricke
Quelle: Dtsch Ärztebl 103: (2006) A3414 - 3418, 2006; 103: 3414-3418
Doc-ID: 1218, 05.03.2008
Klinische Studien
Magnesium and muscle performance in older persons: the InCHIANTI study
BACKGROUND: The role of magnesium in maintaining muscle integrity and function in older adults is largely unknown. OBJECTIVE: We aimed to investigate the relation between serum magnesium concentrations and musc weiter...
Verfasser: Dominguez LJ, Barbagallo M, Lauretani F, Bandinelli S, Bos A, Corsi AM, Simonsick EM, Ferrucci L
Quelle: Am J Clin Nutr., 2006; 84(2): 419-26, PMID: 16895893
Doc-ID: 1196, 04.03.2008
Klinische Studien
Peripheral quantitative computed tomography (pQCT) is useful to measure volumetric bone mineral density (vBMD) distinguishing trabecular from cortical bones as well as quantity of bone geometry. In the present weiter...
Verfasser: Kaji H, Kosaka R, Yamauchi M, Kuno K, Chihara K, Sugimoto T
Quelle: Endocr J., 2005; 52(6): 659-66, PMID: 16410656
Doc-ID: 1203, 04.03.2008
Klinische Studien
A cybernetic approach to osteoporosis in anorexia nervosa
A group of 25 female individuals, who had been admitted to the University Hospital with the diagnosis of anorexia nervosa (AN) 3 to 10 years before, was seen for a follow-up visit in the hospital. These women g weiter...
Verfasser: Fricke O, Tutlewski B, Stabrey A, Lehmkuhl G, Schöenau E
Quelle: J Musculoskelet Neuronal Interact., 2005; 5(2): 155-61, PMID: 15951632
Doc-ID: 1165, 03.03.2008
Weitere Informationen: Original Article
Fachartikel
Diagnostik der Osteoporose Knochendichte bestimmen reicht nicht
Die Festigkeit eines Knochens hängt von vielen Faktoren ab und sie ändert sich je nach Alter des Patienten, mechanischer Beanspruchung und systematischen Gegebenheiten wie dem Hormonspiegel. Daher muß man da weiter...
Verfasser: P. Schneider
Quelle: Der Allgemeinarzt, 2004; 2/04: 112-119
Doc-ID: 1155, 29.02.2008
Fachartikel
Auf dem zweiten interdisziplinären Forum "Knochen und Muskeln - Neue Welten" gab es neue Erkenntnisse über den Zusammenhang von Muskeln und Knochen, die noch weiter wissenschaftlich überprüft werden müssen weiter...
Verfasser: D Felsenberg
Quelle: Mobiles Leben, 2004; 4/04: 14 - 15
Doc-ID: 1157, 29.02.2008
Klinische Studien
Application of bone densitometry to clinical use requires the availability of accessible reference data and is helped by an interpretative framework that is based on bone physiology. The aim of this contributio weiter...
Verfasser: Rauch F, Schöenau E
Quelle: J Musculoskelet Neuronal Interact., 2005; 5(2): 119-26, PMID: 15951627
Doc-ID: 1162, 29.02.2008
Weitere Informationen: Original Article
Klinische Studien
Bone loss and steady state after spinal cord injury: a cross-sectional study using pQCT
Verfasser: Eser P, Schiessl H, Willnecker J
Quelle: J Musculoskelet Neuronal Interact., 2004; 4(2): 197-8, PMID: 15615125
Doc-ID: 1152, 28.02.2008
Weitere Informationen: Original Article
Klinische Studien
Ageing compromises locomotor capacity and is associated with an increased risk of falls. Several lines of evidence indicate that both changes in muscle mass and performance are causative. Most studies, however, weiter...
Verfasser: Runge M, Rittweger J, Russo CR, Schiessl H, Felsenberg D
Quelle: Clin Physiol Funct Imaging., 2004; 24(6): 335-40, PMID: 15522042
Doc-ID: 1148, 28.02.2008
Weitere Informationen: Original Article
Wissenschaftliche Publikationen
The peak bone mass concept: is it still relevant
The peak bone mass concept implies that optimal skeletal development during childhood and adolescence will prevent fractures in late adulthood. This concept is based on the observation that areal bone density i weiter...
Verfasser: Schönau E
Quelle: Pediatr Nephrol., 2004; 19(8): 825-31, PMID: 15197638
Doc-ID: 1138, 26.02.2008
Wissenschaftliche Publikationen
From bone biology to bone analysis
Bone development is one of the key processes characterizing childhood and adolescence. Understanding this process is not only important for physicians treating pediatric bone disorders, but also for clinicians weiter...
Verfasser: Schoenau E, Saggese G, Peter F, Baroncelli GI, Shaw NJ, Crabtree NJ, Zadik Z, Neu CM, Noordam C, Radetti G, Hochberg Z
Quelle: Horm Res., 2004; 61(6): 257-69, PMID: 14963367
Doc-ID: 1136, 26.02.2008
Klinische Studien
Analysis of the functional muscle-bone unit of the forearm in pediatric renal transplant recipients
BACKGROUND: Renal transplantation in children and adolescents is associated with various skeletal complications. The incidence of spontaneous fractures appears to be increased, but the reasons for this are not weiter...
Verfasser: Rüth EM, Weber LT, Schoenau E, Wunsch R, Seibel MJ, Feneberg R, Mehls O, Tönshoff B
Quelle: Kidney Int., 2004; 66(4): 1694-706, PMID: 15458468
Doc-ID: 1140, 26.02.2008
Klinische Studien
Skeletal adaptations in hemiplegic patients
Verfasser: Runge M, Rehfeld G, Schiessl H
Quelle: J Musculoskelet Neuronal Interact., 2004; 4(2): 191-6, PMID: 15615124
Doc-ID: 1132, 25.02.2008
Weitere Informationen: Original Article
Fachartikel
Dioe Festigkeit eines Knochens hängt von vielen Faktoren ab und sie ändert sich je anch Alter der Patienten, mechanischer Beanspruchung und systematischer Gegebenheiten wie dem Hormonhaushalt. Daher muss man weiter...
Verfasser: P. Schneider
Quelle: Allgemeinarzt, 2004;
Doc-ID: 1129, 25.02.2008
Wissenschaftliche Publikationen
Noninvasive Analysis of Bone Mass, Structure, and Strength
Verfasser: JL Ferretti, GR Cointry, RF Capozza
Quelle: Orthopaedic Issues in Osteoporosis CRC Press, 2002; 145 - 167
Doc-ID: 1081, 07.02.2008
Klinische Studien
Verfasser: E Schönau
Quelle: Extracta Orthopaedica, 2002; 11: 20-25
Doc-ID: 1087, 07.02.2008
Wissenschaftliche Publikationen
Verfasser: Frost HM, Schneider P, Schneider R
Quelle: Dtsch Med Wochenschr., 2002; 127(48): 2570-4, PMID: 12457328
Doc-ID: 1091, 07.02.2008
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Klinische Studien
The purpose of this study was to estimate the relation of some noninvasively derived mechanical characteristics of radial bone including architectural parameters for bone strength to grip strength and muscle cr weiter...
Verfasser: Hasegawa Y, Schneider P, Reiners C
Quelle: J Biomech., 2001; 34(4): 497-503, PMID: 11266673
Doc-ID: 1090, 07.02.2008
Wissenschaftliche Publikationen
Peripheral Quantitative Computed Tomography
Verfasser: P Schneider, C Reiners
Quelle: Bone Densitometry and Osteoporosis Springer, 1998; 349-363
Doc-ID: 1093, 07.02.2008
Wissenschaftliche Publikationen
Can exercise prevent osteoporosis
Commonly used definitions of osteoporosis rely upon the measurement of bone mass or bone mineral density and regard the difference between osteopenia and osteoporosis as gradual. An alternative definition has b weiter...
Verfasser: Rittweger J
Quelle: J Musculoskelet Neuronal Interact., 2006; 6(2): 162-6, PMID: 16849827
Doc-ID: 1071, 01.02.2008
Weitere Informationen: Original Article
Klinische Studien
Bone mineral content per muscle cross-sectional area as an index of the functional muscle-bone unit
Bone densitometric data often are difficult to interpret in children and adolescents because of large inter- and intraindividual variations in bone size. Here, we propose a functional approach to bone densitome weiter...
Verfasser: Schoenau E, Neu CM, Beck B, Manz F, Rauch F
Quelle: J Bone Miner Res., 2002; 17(6): 1095-101, PMID: 12054165
Doc-ID: 1053, 30.01.2008
Klinische Studien
The muscle-bone relationship: methods and management - perspectives in glycogen storage disease
Currently bone development is commonly presented as a process leading to the "accumulation of peak bone mass". Consequently, the usual approach to a suspected bone disorder in a child is to address the question weiter...
Verfasser: Schönau E, Schwahn B, Rauch F
Quelle: Eur J Pediatr., 2002; 161 Suppl 1: S50-2, PMID: 12373571
Doc-ID: 1062, 30.01.2008
Wissenschaftliche Publikationen
The "muscle-bone unit" in children and adolescents: a 2000 overview
In former views hormones, calcium, vitamin D and other humoral and nonmechanical agents dominated control of postnatal bone strength (and "mass") in children and adolescents. However later evidence that led to weiter...
Verfasser: Frost HM, Schönau E
Quelle: J Pediatr Endocrinol Metab., 2000; 13(6): 571-90, PMID: 10905381
Doc-ID: 1027, 29.01.2008
Klinische Studien
Bone-muscle strength indices for the human lower leg
This cross-sectional study is based on images from the lower leg as assessed by peripheral quantitative computer tomography (pQCT). Measurements were performed in 39 female and 38 male control subjects and 15 f weiter...
Verfasser: Rittweger J, Beller G, Ehrig J, Jung C, Koch U, Ramolla J, Schmidt F, Newitt D, Majumdar S, Schiessl H, Felsenberg D
Quelle: Bone., 2000; 27(2): 319-26, PMID: 10913929
Doc-ID: 1035, 29.01.2008
Klinische Studien
Bilateral bone characteristics of the humerus (proximal, shaft, and distal sites) and radius (shaft and distal sites) in 12 former Finnish national-level male tennis players (mean age 30 years) and their 12 age weiter...
Verfasser: Haapasalo H, Kontulainen S, Sievänen H, Kannus P, Järvinen M, Vuori I
Quelle: Bone., 2000; 27(3): 351-7, PMID: 10962345
Doc-ID: 1028, 29.01.2008
Klinische Studien
Densitometric and tomographic analyses of musculoskeletal interactions in humans
Previous studies with standard densitometry (DXA) have suggested that the bone mass is strongly dependent on the muscle mass in the species, following a similar relationship at any age and sex hormones or relat weiter...
Verfasser: Ferretti JL, Capozza RF, Cointry GR, Capiglioni R, Roldan EJ, Zanchetta JR
Quelle: J Musculoskelet Neuronal Interact., 2000; 1(1): 31-4, PMID: 15758522
Doc-ID: 1031, 29.01.2008
Weitere Informationen: Original Article
Klinische Studien
Musculoskeletal Interactions in Normal Subjects and Dialysis Patients
Verfasser: CR Russo
Quelle: MusculoSkeletal Interactions, 2000; 2: 105 - 110
Doc-ID: 1030, 29.01.2008
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Klinische Studien
On new opportunities for absorptiometry
Mechanical loads cause bone strains; and muscle forces, not body weight, cause the largest strains. The strains help to control the effects of bone modeling and remodeling on bone strength and "mass." When stra weiter...
Verfasser: Ferretti JL, Schiessl H, Frost HM
Quelle: J Clin Densitom., 1998; 1(1): 41-53, PMID: 15304912
Doc-ID: 1024, 29.01.2008
Klinische Studien
Estrogen and bone-muscle strength and mass relationships
The largest voluntary loads on bones come from muscles. To adapt bone strength and mass to them, special strain threshold ranges determine where modeling adds and strengthens bone, and where remodeling conserve weiter...
Verfasser: Schiessl H, Frost HM, Jee WS
Quelle: Bone., 1998; 22(1): 1-6, PMID: 9437507
Doc-ID: 998, 29.01.2008
Wissenschaftliche Publikationen
Verfasser: P.Schneider, W. Börner
Quelle: Osteoporosis, 1990; 59: 921-924
Doc-ID: 974, 24.01.2008
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Wissenschaftliche Publikationen
Quelle: Acta Orthop Scand, 2002; Suppl 303) 43:: 44 - 52
Doc-ID: 864, 22.01.2008
Weitere Informationen: Original Article
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Grundlagenstudien
Rodent model for investigating the effects of estrogen on bone and muscle relationship during growth
It has been reported that in humans from about 11-12 years of age, bone mass begins to increase faster in girls than in boys with the same muscle mass, and by 14-15 years of age, bone mass per unit mass of musc weiter...
Verfasser: Wang L, McMahan CA, Banu J, Okafor MC, Kalu DN
Quelle: Calcif Tissue Int., 2003; 72(2): 151-5, PMID: 12469248
Doc-ID: 687, 10.01.2008
Pressestimmen
Bilder Hufelandpreis-Verleihung
Quelle: Novotec Medical, 2002;
Doc-ID: 629, 04.01.2008
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Pressestimmen
Verfasser: Weinbauer GF
Quelle: Mitteilungen der Deutsche Gesellschaft für Endokrinologie, 2003; 27/3:
Doc-ID: 631, 04.01.2008
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Pressestimmen
Die funktionelle Muskel-Knochen-Einheit im Kindes- und Jugendalter: Konsequenzen für Prävention und Klassifikation der Osteoporose weiter...
Quelle: Mobiles Leben, 2003;
Doc-ID: 623, 04.01.2008
Pressestimmen
Ein Scherbenhaufen - Brüchige Knochen: Wie die Gesundheitsindustrie irrte
Verfasser: Hobom B
Quelle: FAZ, 2003;
Doc-ID: 630, 04.01.2008
Pressestimmen
Mit dem Hufeland-Reis 2002 wurden jetzt drei Kölner Pädiater ausgezeichnet. Den mit 20000Euro dotierten, von der Deutschen Ärzteversicherung AG gestiftete Preis zur Förderung der Präventivmedizin erhielten weiter...
Verfasser: sk
Quelle: Pädiartische Nachrichten, 2003;
Doc-ID: 622, 04.01.2008
Pressestimmen
Hufeland-Preis 2002: Bewegung ist Osteoporose-Präventation
Verfasser: dah
Quelle: Rheinisches Ärzteblatt, 2003;
Doc-ID: 621, 04.01.2008
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Pressestimmen
Hufeland-Preis für Kölner Forschungsgruppe - Neuer Erkenntnisse zur Prävention der osteoporose
Professor Eckhard Schönau, Dr. Christina Neu und Privatdozent Dr. Frank Rauch, Klinik und Poliklinik für Kinderheilkunde, sind mit dem Huffeland-Preis 2002 ausgezeichnet worden. Der mit 20.000 Euro dotierte, weiter...
Verfasser: unik
Quelle: Kölner Universitäts Jurnal, 2003; 2:
Doc-ID: 626, 04.01.2008
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Pressestimmen
Drei Mediziner der Uni-Klinik mit Hufeland-PReis ausgezeichnet weiter...
Verfasser: Kracht E
Quelle: Kölnische Rundschau, 2003;
Doc-ID: 625, 04.01.2008
Wissenschaftliche Publikationen
Verfasser: Schönau E, Rauch F,
Quelle: Hufeland-Preis Jury, 2002;
Doc-ID: 634, 04.01.2008
Fachartikel
Knochen und Muskeln - neue Welten
Im November vergangenen Jahres fand ein erster Kongress zum Thema Muskel und Knochen statt. Prof. Dr. med. Dieter Felsenberg vom Zentrum für Muskel- und Knochen-Forschung Berlin, war einer der initiatoren. Mob weiter...
Verfasser: Landschek I
Quelle: Mobiles Leben, 2002; 1:
Schlagworte: BBR, Berlin BedRest Study, ESA, Galileo Space
Doc-ID: 240, 16.12.2007
Grundlagenstudien
Modulation of Strain Sensing: A New Approach for the Treatment of Osteoporosis
Verfasser: Gasser JA
Quelle: J Musculoskelet Neuronal Interact., 2000; 2: 105-110
Doc-ID: 490, 10.12.2007
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Wissenschaftliche Publikationen
What is new in neuro-musculoskeletal interactions: Neuromuscular Science
Verfasser: Rittweger J, Rauch F
Quelle: J Musculoskelet Neuronal Interact., 2002; 2(2): 177-80, PMID: 15758468
Schlagworte: Mechanostat
Doc-ID: 356, 04.12.2007
Weitere Informationen: Original Article
Klinische Studien
Klinisch bedeutsame Veränderungen des Knochenstatus resultieren meist in einer Verminderung der Knochendichte bis hin zu einer manifesten Osteoporose. Heutzutage werden zur Überprüfung des Knochenstatus häu weiter...
Verfasser: Wolf D
Quelle: 2003;
Schlagworte: Zusammenhang SSI, Muskelkraft / Drehmoment
Doc-ID: 335, 03.12.2007
Weitere Informationen: Original Article
Grundlagenstudien
Mobil bleiben - Pflege bei Gehstörungen und Sturzgefahr
Die Selbstständigkeit älterer Menschen wird durch kaum ein anderes Problem so stark bedroht wie durch die Einschränkung der Bewegungsfähigkeit und die damit verbundene Sturzgefahr. Stürze im Alter sind zud weiter...
Verfasser: Runge M, Rehfeld G
Quelle: Schlütersche Verlag , ISBN 3-87706-597-X, 2001;
Doc-ID: 318, 02.12.2007
Klinische Studien
Mechanography--a new device for the assessment of muscle function in pediatrics
The development of the musculoskeletal system in children and adolescents became an important topic in the field of pediatric research when the connections between muscle force and bone diseases were revealed. weiter...
Verfasser: Fricke O, Weidler J, Tutlewski B, Schoenau E
Quelle: Pediatr Res., 2006; 59(1): 46-9, PMID: 16327004
Schlagworte: Mechanography
Doc-ID: 304, 02.12.2007
Wissenschaftliche Publikationen
Defining osteopenias and osteoporoses: another view (with insights from a new paradigm)
This article suggests classifying "osteoporoses" by their biomechanical pathogenesis instead of by their severity or their accompanying medical conditions. (A) In a "true osteoporosis," bone fragility would inc weiter...
Verfasser: Frost HM
Quelle: Bone., 1997; 20(5): 385-91, PMID: 9145234
Schlagworte: Mechanostat
Doc-ID: 289, 02.12.2007
Klinische Studien
Multifactorial pathogenesis of falls as a basis for multifactorial interventions
Verfasser: Runge M, Schacht E
Quelle: J Musculoskelet Neuronal Interact., 2005; 5(2): 127-34, PMID: 15951628
Schlagworte: Mechanography
Doc-ID: 275, 02.12.2007
Weitere Informationen: Original Article
Fachartikel
New Insights about the Relationship between Bone Strength and Muscle Strength
Verfasser: Schiessl H, Willnecker J
Quelle: 2000;
Doc-ID: 258, 02.12.2007
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Fachartikel
Osteoporose - Dogmen hinterfragt
Verfasser: Runge M
Quelle: Der Hausarzt, 2001; 2: 26 - 32
Doc-ID: 201, 01.12.2007
