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J Clin Densitom., 2008; PMID: 18164637

Peripheral Quantitative Computed Tomography of the Tibia: Pediatric Reference Values

Moyer-Mileur LJ, Quick JL, Murray MA
Center for Pediatric Nutrition Research.

Abstract

Peripheral quantitative computed tomography (pQCT) has been used in a number of pediatric studies. Reference data for children are primarily limited to the radius. The purpose of this study was to establish normal reference ranges for pQCT measurements of the tibia for children. A cross-sectional sample of healthy, white, non-Hispanic children aged 5-18 years (n=416; 197 boys) was measured at the distal tibia metaphysis and diaphysis by pQCT to assess trabecular and cortical bone, respectively. Differences were determined between and within genders by height for bone geometry, density, and strength. Height-specific normal ranges were calculated, and gender-specific centile curves were generated. A positive, linear relationship was found between tibia cortical bone geometry and strength parameters and height (r(2)>/=0.58, p<0.001), with mean values greater for boys than girls (p
Product groups: pQCT Bone Density & Bone Geometry
Topics: Clinical Studies, Clinical Application, Paediatrics, Medical Faculties, Diagnostics with Leonardo & pQCT, Therapy & Prevention with Galileo®
Keywords: pädiatrie
Doc-ID: 1114,