Scientific publications for the application area muscle and bone
Here you will find all scientific publications, listed by date of last update. This category currently includes 125 entries.
Literature (125)
Scientific Publications
OBJECTIVE: To determine the reliability of ground reaction force during a vertical jump. DESIGN AND SETTING: Two test sessions 48 hours apart in which subjects performed five maximal vertical jumps with their r weiter...
Author: Cordova ML, Armstrong CW
Source: J Athl Train, 2010; 31(4): 342-5, PMID: 16558421
Doc-ID: 2969,
More information: Original Article
Scientific Publications
The dynamics of bone structure development during pubertal growth.
The pubertal growth spurt is a time of rapid changes in bone length, mass and structure, followed by the cessation of longitudinal growth. The two best studied anatomical areas in this respect are the metaphyse weiter...
Author: Rauch F
Source: J Musculoskelet Neuronal Interact, 2012; 12(1): 1-6, PMID: 22373945
Doc-ID: 2904,
More information: Original Article
Scientific Publications
Das vorliegende Buch bietet einen umfassenden Überblick zum Thema Gesundheit, Gesundheitsmanagement und Gesundheitsförderung in Unternehmen. Aufgrund der steigenden Altersstruktur der Erwerbspersonen nehmen a weiter...
Author: Seitz D.
Source: 3639384326, 2011;
Keywords: Betriebliche Gesundheitsförderung
Doc-ID: 2779,
Scientific Publications
Why bones bend but don"t break.
The musculoskeletal system is adept at dissipating potentially damaging energy that could accelerate fracture consequent to multiple loading cycles. Microstructural damage reduces bone"s residual properties, bu weiter...
Author: Burr DB
Source: J Musculoskelet Neuronal Interact, 2011; 11(4): 270-85, PMID: 22130136
Doc-ID: 2776,
More information: Original Article
Scientific Publications
The purpose of this study was to investigate the effect of Juvenile Idiopathic Arthritis (JIA) on lower limb muscle activity during a countermovement jump (CMJ). Two groups of patient data were collected; 6 pat weiter...
Author: Dwyer KD; Kennedy MJ; Lamontagne M; Roth J
Source: Portuguese Journal of Sport Sciences, ISBS 2011, 2011; 11(2): 721-3
Doc-ID: 2754,
More information: Original Article
Scientific Publications
Vibration exercise: the potential benefits
The aim of this review was to examine the physiological effects of vibration exercise (VbX), including the cardiovascular indices and to elucidate its potential use for those with compromised health. VbX has lo weiter...
Author: Cochrane DJ
Source: Int J Sports Med, 2011; 32(2): 75-99, PMID: 21165804
Doc-ID: 2686,
Scientific Publications
What do we currently know from in vivo bone strain measurements in humans
Bone strains are the most important factors for osteogenic adaptive responses. During the past decades, scientists have been trying to describe the relationship between bone strain and bone osteogenic responses weiter...
Author: Yang PF, Brüggemann GP, Rittweger J
Source: J Musculoskelet Neuronal Interact., 2011; 11(1): 8-20, PMID: 21364270
Doc-ID: 2584,
More information: Original Article
Scientific Publications
Effects of oxidation on the power of chemically skinned rat soleus fibres
Oxidation alters calcium sensitivity, and decreases maximum isometric force (Po) and shortening velocity (Vmax) of single muscle fibres. To examine the effect of oxidation on the curvature of the force-velocity weiter...
Author: Gilliver SF, Jones DA, Rittweger J, Degens H
Source: J Musculoskelet Neuronal Interact., 2010; 10(4): 267-73, PMID: 21116063
Doc-ID: 2485,
More information: Original Article
Scientific Publications
Determinants of peak muscle power: effects of age and physical conditioning
The relationships between absolute peak muscle power (Wpeak), muscle cross sectional area (CSAtot, i.e. the sum of both thigh and calf CSA) and muscle high energy phosphate concentration (adenosine 5"-triphosph weiter...
Author: Ferretti G, Narici MV, Binzoni T, Gariod L, Le Bas JF, Reutenauer H, Cerretelli P
Source: Eur J Appl Physiol Occup Physiol., 1994; 68(2): 111-5, PMID: 8194538
Doc-ID: 2462,
Scientific Publications
Differential effects of countermovement magnitude and volitional effort on vertical jumping
The importance of vertical jumping in sport and rehabilitative medicine is widely recognized. Despite the ample use of jump tests to assess neuromuscular function, the differential effects of muscular activatio weiter...
Author: Salles AS, Baltzopoulos V, Rittweger J
Source: Eur J Appl Physiol., 2010; PMID: 20882293
Doc-ID: 2418,
Scientific Publications
Whole-body vibration (WBV) is receiving increasing interest as a therapeutic modality to improve neuromuscular performance or to increase bone mass or density. In order to help improve the quality of reports ab weiter...
Author: Rauch F, Sievanen H, Boonen S, Cardinale M, Degens H, Felsenberg D, Roth J, Schoenau E, Verschueren S, Rittweger J
Source: J Musculoskelet Neuronal Interact., 2010; 10(3): 193-8, PMID: 20811143
Doc-ID: 2392,
More information: Original Article
Scientific Publications
Reliability of measures obtained during single and repeated countermovement jumps
PURPOSE: To establish the reliability of various measures obtained during single and repeated countermovement jump (CMJ) performance in an elite athlete population. METHODS: Two studies, each involving 15 elite weiter...
Author: Cormack SJ, Newton RU, McGuigan MR, Doyle TL
Source: Int J Sports Physiol Perform., 2008; 3(2): 131-44, PMID: 19208922
Doc-ID: 2121,
More information: Original Article
Scientific Publications
Intersession Reliability of Vertical Jump Height
Introduction: The usefulness of measurements in research depends on the extent to which the researcher can rely on data as accurate and meaningful indicators of a behavior. In short, the measurements have to weiter...
Author: SØRENSEN H, IVERSEN K
Source: 14th annual Congress ECSS 2009, Oslo, Book of Abstracts, 2009;
Doc-ID: 2120,
Scientific Publications
Changes in muscle mass and strength after menopause
Menopause is associated with a natural decline in estrogen, that increases visceral fat mass, decreases bone mass density, muscle mass, and strength. This review will examine the role of menopause transition an weiter...
Author: Maltais ML, Desroches J, Dionne IJ
Source: J Musculoskelet Neuronal Interact., 2009; 9(4): 186-97, PMID: 19949277
Doc-ID: 2108,
More information: Original Article
Scientific Publications
The role of changes in mechanical usage set points in the pathogenesis of osteoporosis
Mechanical usage (MU) effects on modeling drifts and BMU-based remodeling affect bone mass in defined ways. Decreased MU stops additions of bone by modeling and increases removal of bone next to marrow by remod weiter...
Author: Frost HM
Source: J Bone Miner Res., 1992; 7(3): 253-61, PMID: 1585826
Doc-ID: 2077,
Scientific Publications
Skeletal adaptations during growth
NASA: The authors examine the role of mechanical usage in skeletal development. Principle mechanisms of bone physiology include longitudinal bone growth; modeling drifts; micromodeling; remodeling by the basic weiter...
Author: Jee WS, Frost HM
Source: Triangle., 1992; 31(2/3): 77-88, PMID: 11539347
Doc-ID: 2078,
Scientific Publications
Author: Frost HM, Ferretti JL, Jee WS
Source: Calcif Tissue Int., 1998; 62(1): 1-7, PMID: 9405724
Doc-ID: 2079,
Scientific Publications
Mechanical efficiency during repetitive vertical jumping
The purpose of this study was to compare mechanical efficiency between repeated static jumps (SJ), countermovement jumps (CMJ), drop jumps from 75% of maximum CMJ jump height (75DJ) and drop jumps from 125% of weiter...
Author: McCaulley GO, Cormie P, Cavill MJ, Nuzzo JL, Urbiztondo ZG, McBride JM
Source: Eur J Appl Physiol., 2007; 101(1): 115-23, PMID: 17530275
Doc-ID: 2055,
Scientific Publications
Contraction times and fibre types in intact human muscle
Twitches were recorded in situ in muscles of normal humans by small transducers connected to a needle in the tendon. The twitches were elicited by stimuli in the endplate zone, the force of the smallest twitche weiter...
Author: Buchthal F, Schmalbruch H.
Source: Acta Physiol Scand, 1970; 79(4): 435-52, PMID: 5472111
Keywords: Contraction Time, muscle function
Doc-ID: 1995,
Scientific Publications
Isometric contraction of the abductor digiti minimi muscle in man
Isometric contraction of the abductor digiti minimi muscle (ADM) has been studied in six normal subjects. Twitch contraction times of ADM ranged from 60 to 68 ms and twitch torque ranged from 2·33 to 6·24 x 1 weiter...
Author: Burke D, Skuse NF, Lethlean AK
Source: J Neurol Neurosurg Psychiatry., 1974; 37(7): 825-34, PMID: 4852602
Doc-ID: 1996,
More information: Original Article
Scientific Publications
Enhanced Skeletal Parameters in Gymnasts Are Not Attributable to Self-Selection Bias
Author: Dowthwaite J, Gero N, Rosenbaum P, Scerpella T
Source: ASBMR, 2009;
Doc-ID: 1956,
Scientific Publications
Whole-body vibration training is a method for muscle strengthening that is increasingly used in a variety of clinical situations. Key descriptors of vibration devices include the frequency, the amplitude, and t weiter...
Author: Rauch F
Source: Dev Med Child Neurol., 2009; 51 Suppl 4: 166-8, PMID: 19740225
Doc-ID: 1951,
Scientific Publications
In vivo measurement-based estimations of the human Achilles tendon moment arm
The aim of the present study was to estimate and compare in vivo measurement-based Achilles tendon moment arm lengths at rest and during isometric plantarflexion maximum voluntary contraction (MVC) using the ce weiter...
Author: Maganaris CN, Baltzopoulos V, Sargeant AJ
Source: Eur J Appl Physiol., 2000; 83(4 -5): 363-9, PMID: 11138576
Keywords: maximum internal forces on tibia
Doc-ID: 1876,
Scientific Publications
In vivo Achilles tendon loading during jumping in humans
Elastic behaviour of the human tendomuscular system during jumping was investigated by determination of the in vivo Achilles tendon force. A buckle-type transducer was implanted under local anaesthesia around t weiter...
Author: Fukashiro S, Komi PV, Järvinen M, Miyashita M
Source: Eur J Appl Physiol Occup Physiol., 1995; 71(5): 453-8, PMID: 8565978
Doc-ID: 1877,
Scientific Publications
Biomechanical loading of Achilles tendon during normal locomotion
Direct in vivo Achilles tendon force measurements open up new possibilities for understanding the loading of the Achilles tendon during natural locomotion. This article describes how these human experiments can weiter...
Author: Komi PV, Fukashiro S, Järvinen M
Source: Clin Sports Med., 1992; 11(3): 521-31, PMID: 1638639
Doc-ID: 1879,
Scientific Publications
BACKGROUND: Several reports give evidence that the perichondral ossificiation of bone tubes (modeling) strongly depends on muscular forces in children and adolescents. The present analyses intend to investigate weiter...
Author: Fricke O, Beccard R, Semler O, Land C, Stabrey A, Tutlewski B, Remer T, Schoenau E
Source: Horm Res., 2008; 70(5): 285-93, PMID: 18824867
Doc-ID: 1855,
Scientific Publications
Mechanical influences on bone development in children
This review focuses on methodological concepts in the evaluation of skeletal muscle function and on adaptation. It is now thought that the critical property of bone is strength rather than weight, and that cont weiter...
Author: Schoenau E, Fricke O
Source: Eur J Endocrinol., 2008; 159 Suppl 1: S27-31, PMID: 18787052
Doc-ID: 1856,
More information: Original Article
Scientific Publications
BACKGROUND/AIMS: The present analyses intend to clarify if gender and puberty modify the relationship between bone development (modeling and remodeling) and fat mass at the forearm. METHODS: Data were collected weiter...
Author: Fricke O, Sumnik Z, Tutlewski B, Stabrey A, Remer T, Schoenau E
Source: Horm Res., 2008; 70(2): 105-11, PMID: 18547958
Doc-ID: 1857,
Scientific Publications
What is new in neuro-musculoskeletal interactions: mechanotransduction, microdamage and repair
Author: Rittweger J
Source: J Musculoskelet Neuronal Interact., 2007; 7(2): 191-3, PMID: 17627090
Doc-ID: 1847,
More information: Original Article
Scientific Publications
What is new in neuro-musculoskeletal interactions: Research with impact
Author: Rauch F, Rittweger J
Source: J Musculoskelet Neuronal Interact., 2001; 1(4): 393-8, PMID: 15758490
Doc-ID: 1848,
More information: Original Article
Scientific Publications
What is new in neuro-musculoskeletal interactions: Strain on Bones
Author: Rauch F, Rittweger J
Source: J Musculoskelet Neuronal Interact., 2002; 2(5): 489-92, PMID: 15758418
Doc-ID: 1849,
More information: Original Article
Scientific Publications
What is new in neuro-musculoskeletal interactions: On soups, hips and humeri
Author: Rittweger J, Rauch F
Source: J Musculoskelet Neuronal Interact., 2003; 3(1): 101-4, PMID: 15758372
Doc-ID: 1850,
More information: Original Article
Scientific Publications
What is new in neuro-musculoskeletal interactions: Bye-bye, density?
Author: Rauch F
Source: J Musculoskelet Neuronal Interact., 2003; 3(3): 258-60, PMID: 15758350
Doc-ID: 1851,
More information: Original Article
Scientific Publications
Revival of bone strength: the bottom line
Author: Järvinen TL, Sievänen H, Jokihaara J, Einhorn TA
Source: J Bone Miner Res., 2005; 20(5): 717-20, PMID: 15824843
Doc-ID: 1730,
Scientific Publications
Updates on improvement of human athletic performance: focus on world records in athletics
INTRODUCTION: Progression of world records (WRs) in athletics is a reliable mean to assess the potentiality of the human body, which also reflects how society has evolved over time and will continue to evolve. weiter...
Author: Lippi G, Banfi G, Favaloro EJ, Rittweger J, Maffulli N
Source: Br Med Bull., 2008; 87: 7-15, PMID: 18723588
Doc-ID: 1779,
Scientific Publications
Drop jumping. II. The influence of dropping height on the biomechanics of drop jumping
In the literature, athletes preparing for explosive activities are recommended to include drop jumping in their training programs. For the execution of drop jumps, different techniques and different dropping he weiter...
Author: Bobbert MF, Huijing PA, van Ingen Schenau GJ
Source: Med Sci Sports Exerc., 1987; 19(4): 339-46, PMID: 3657482
Doc-ID: 1648,
Scientific Publications
Ten years muscle-bone hypothesis: What have we learned so far? -Almost a Festschrift-
The importance of mechanical stimuli for bone is widely appreciated. Mechanostat theory proposes a negative feedback system to explain the adaptation of bone by homeostatic control of peak strains. However, no weiter...
Author: Rittweger J
Source: J Musculoskelet Neuronal Interact., 2008; 8(2): 174-8, PMID: 18622086
Doc-ID: 1650,
More information: Original Article
Scientific Publications
The Utah Paradigm of Skeletal Physiology with its key component, the mechanostat hypothesis, suggest plausible explanations of some of the tissue-level changes occurring from combining selected non-mechanical a weiter...
Author: Jee WS, Tian XY
Source: J Musculoskelet Neuronal Interact., 2005; 5(2): 110-8, PMID: 15951626
Doc-ID: 1641,
More information: Original Article
Scientific Publications
The view that nonmechanical agents dominate control of osteoblasts and osteoclasts and thus postnatal changes in bone strength and mass (agent --> effector cells --> disease) is obsolete. Nonmechanical agents i weiter...
Author: Jee WS
Source: J Musculoskelet Neuronal Interact., 2000; 1(1): 11-3, PMID: 15758518
Doc-ID: 1644,
More information: Original Article
Scientific Publications
Author: P.D. Delmas, N. Khaltaev, M. Arriagada, M.L. Brandi, J. Cannata, E. Lau,
R. Lederman, R. Lorenc, H. Minne, J. Morales-Torres, H. Morii,
P. Sambrook, T. Torralba, J. Zanchetta, J.Y. Reginster
Source: Musculoskelet Neuronal Interact, 2005; 5(2): 105-109
Doc-ID: 1585,
More information: Original Article
Scientific Publications
Bone growth in length and width: the Yin and Yang of bone stability
Bone growth in length is primarily achieved through the action of chondrocytes in the proliferative and hypertrophic zones of the growth plate. Longitudinal growth is controlled by systemic, local paracrine and weiter...
Author: Rauch F
Source: J Musculoskelet Neuronal Interact., 2005; 5(3): 194-201, PMID: 16172510
Doc-ID: 1586,
More information: Original Article
Scientific Publications
Variation in the density of the femoral diaphysis with age
1. A detailed study of density variations with age in cortical bone samples from different areas of the femoral diaphysis has been carried out. 2. Bone of relatively high density and, conversely, of low densit weiter...
Author: Atkinson PJ, Weatherell JA
Source: J Bone Joint Surg Br., 1967; 49(4): 781-8, PMID: 6073195
Doc-ID: 1590,
Scientific Publications
In a 1960 paradigm of skeletal physiology, effector cells (chondroblasts, fibroblasts, osteoblasts, osteoclasts, etc.) regulated by nonmechanical agents wholly determined the architecture, strength, and health weiter...
Author: Frost HM
Source: J Bone Miner Metab., 2000; 18(6): 305-16, PMID: 11052462
Doc-ID: 1599,
Scientific Publications
Why the ISMNI and the Utah paradigm? Their role in skeletal and extraskeletal disorders
Besides bringing problems, aging can let the mind"s eye see more clearly than before, and it can let us express ourselves better. As age, experience and common sense examine today"s skeletal medicine and surger weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2000; 1(1): 5-9, PMID: 15758517
Doc-ID: 1601,
More information: Original Article
Scientific Publications
The Utah paradigm on animal models of skeletal disorders: quo vadis
Skeletal disorders that need effective studies in suitable animal models include "osteoporosis", arthroses and hard and soft tissue healing. For people doing or analyzing such studies this article provides a br weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2001; 1(3): 185-91, PMID: 15758492
Doc-ID: 1602,
More information: Original Article
Scientific Publications
Why should many skeletal scientists and clinicians learn the Utah paradigm of skeletal physiology
Adding later facts and ideas to a universally accepted "1960 paradigm" of skeletal physiology led to the still-evolving "Utah paradigm". The ASBMR"s William Neuman award in 2001 to one of the latter paradigm"s weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2001; 2(2): 121-30, PMID: 15758459
Doc-ID: 1603,
More information: Original Article
Scientific Publications
The pathogenesis of osteogenesis imperfecta (OI) baffled physiologists and physicians for over a century. Most past efforts to explain it depended heavily on cell and molecular biology and on changes in the mat weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2003; 3(1): 1-7, PMID: 15758360
Doc-ID: 1604,
More information: Original Article
Scientific Publications
On the strength-safety factor (SSF) for load-bearing skeletal organs
The strength of healthy postnatal mammalian load-bearing bones, growth plates, joints, fascia, ligaments and tendons exceeds the minimum strength needed to keep voluntary mechanical usage from breaking or ruptu weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2003; 3(2): 136-40, PMID: 15758353
Doc-ID: 1605,
More information: Original Article
Scientific Publications
Perspective: genetic and hormonal roles in bone disorders: insights of an updated bone physiology
In 1997 Professor J. Gorski suggested endocrinology needed new paradigms (Endocrine News 1997; 22:4,12). "Connecting the dots" between diverse facts and ideas drawn from many lines of inquiry, plus accumulating weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2003; 3(2): 118-35, PMID: 15758352
Doc-ID: 1606,
More information: Original Article
Scientific Publications
Here an octogenarian voice from the past argues that the physiology of fascia, ligaments and tendons has strong and useful analogs in some general features of bone physiology, including the latter"s tissue-leve weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2003; 3(3): 201-9, PMID: 15758342
Doc-ID: 1607,
More information: Original Article
Scientific Publications
Coming changes in accepted wisdom about "osteoporosis"
Here a voice from the past suggests 28 changes that will affect how people study, manage, classify and think about "osteoporoses" today. Those changes depend mainly on two things: (i) "Connecting the dots" betw weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2004; 4(1): 78-85, PMID: 15615080
Doc-ID: 1608,
More information: Original Article
Scientific Publications
From Wolff"s law to the Utah paradigm: insights about bone physiology and its clinical applications
Efforts to understand our anatomy and physiology can involve four often overlapping phases. We study what occurs, then how, then ask why, and then seek clinical applications. In that regard, in 1960 views, bone weiter...
Author: Frost HM
Source: Anat Rec., 2001; 262(4): 398-419, PMID: 11275971
Doc-ID: 1609,
Scientific Publications
Musculoskeletal responses of 2-year-old Thoroughbred horses to early training. Conclusions
This paper summarises and presents in context the main findings of an extensive series of studies of early training lasting 13 weeks in which the tissue responses of 2-year-old Thoroughbred horses were assessed weiter...
Author: Firth EC, Rogers CW
Source: N Z Vet J., 2005; 53(6): 377-83, PMID: 16317437
Doc-ID: 1620,
Scientific Publications
Vibration training is commonly expected to induce an active muscle contraction via a complex reflex mechanism. In calf muscles of 20 untrained subjects, the additional energy consumption in response to vibratio weiter...
Author: Zange J, Haller T, Müller K, Liphardt AM, Mester J
Source: Eur J Appl Physiol., 2008; PMID: 18953563
Doc-ID: 1576,
Scientific Publications
Human remains from peat bogs, called "bog bodies," have yielded valuable insights into human history because of their excellent preservation of soft tissue. On the other hand, the acidic environment of the peat weiter...
Author: Schilling AF, Kummer T, Marshall RP, Bauerochse A, Jopp E, Pueschel K, Amling M
Source: Am J Phys Anthropol., 2008; 135(4): 479-83, PMID: 18000892
Doc-ID: 1502,
Scientific Publications
Author: Sievänen H, Kannus P, Järvinen TL
Source: PLoS Med., 2007; 4(3): e27, PMID: 17341126
Doc-ID: 1517,
More information: Original Article
Scientific Publications
Relative strength of the tibia and fibula and locomotor behavior in hominoids
The fibula has rarely been considered in comparative morphological studies, probably due to its relatively minor role in carrying mechanical loads. However, some differences in morphology (and inferred function weiter...
Author: Marchi D
Source: J Hum Evol., 2007; 53(6): 647-55, PMID: 17675139
Doc-ID: 1331,
Scientific Publications
Risk factors for falls among elderly persons living in the community
To study risk factors for falling, we conducted a one-year prospective investigation, using a sample of 336 persons at least 75 years of age who were living in the community. All subjects underwent detailed cli weiter...
Author: Tinetti ME, Speechley M, Ginter SF
Source: N Engl J Med., 1988; 319(26): 1701-7, PMID: 3205267
Doc-ID: 1288,
Scientific Publications
Bone mineral density in chimpanzees, humans, and Japanese macaques
We performed a comparative study of bone mechanical properties in the radii of chimpanzees (Pan troglodytes), humans (Homo sapiens), and Japanese macaques (Macaca fuscata) using peripheral quantitative computed weiter...
Author: Kikuchi Y, Udono T, Hamada Y
Source: Primates., 2003; 44(2): 151-5, PMID: 12687479
Doc-ID: 1257,
Scientific Publications
Measurement of bone density and bone strength with pQCT
Author: J. Willnecker
Source: Novel approaches towards primate toxicology, 2006; 13 - 19
Doc-ID: 1213,
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Scientific Publications
From bone biology to bone analysis
Bone development is one of the key processes characterizing childhood and adolescence. Understanding this process is not only important for physicians treating pediatric bone disorders, but also for clinicians weiter...
Author: Schoenau E, Saggese G, Peter F, Baroncelli GI, Shaw NJ, Crabtree NJ, Zadik Z, Neu CM, Noordam C, Radetti G, Hochberg Z
Source: Horm Res., 2004; 61(6): 257-69, PMID: 14963367
Doc-ID: 1136,
Scientific Publications
The peak bone mass concept: is it still relevant
The peak bone mass concept implies that optimal skeletal development during childhood and adolescence will prevent fractures in late adulthood. This concept is based on the observation that areal bone density i weiter...
Author: Schönau E
Source: Pediatr Nephrol., 2004; 19(8): 825-31, PMID: 15197638
Doc-ID: 1138,
Scientific Publications
Noninvasive Analysis of Bone Mass, Structure, and Strength
Author: JL Ferretti, GR Cointry, RF Capozza
Source: Orthopaedic Issues in Osteoporosis CRC Press, 2002; 145 - 167
Doc-ID: 1081,
Scientific Publications
Author: JL Ferretti, HM Frost
Source: CRC Press 2002 (202 - 217)
Orthopaedic Issues in Osteoporosis CRC Press, 2002; 202 - 217
Doc-ID: 1083,
Scientific Publications
Quantitative Bestimmung der Knochenmasse: heutiger Stand und Fallstricke der Methoden
Author: P Schneider, C Reiners
Source: Med Welt (1998) 49: 157 - 163, 1998; 49: 157-163
Doc-ID: 1088,
Scientific Publications
Author: Frost HM, Schneider P, Schneider R
Source: Dtsch Med Wochenschr., 2002; 127(48): 2570-4, PMID: 12457328
Doc-ID: 1091,
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Scientific Publications
Peripheral Quantitative Computed Tomography
Author: P Schneider, C Reiners
Source: Bone Densitometry and Osteoporosis Springer, 1998; 349-363
Doc-ID: 1093,
Scientific Publications
Can exercise prevent osteoporosis
Commonly used definitions of osteoporosis rely upon the measurement of bone mass or bone mineral density and regard the difference between osteopenia and osteoporosis as gradual. An alternative definition has b weiter...
Author: Rittweger J
Source: J Musculoskelet Neuronal Interact., 2006; 6(2): 162-6, PMID: 16849827
Doc-ID: 1071,
More information: Original Article
Scientific Publications
New Noninvasive pQCT Devices to Determine Bone Structure
Author: G Tysarczyk-Niemeyer
Source: J Jpn Soc Bone Morphom, 1997; 7: 97-105
Doc-ID: 1000,
Scientific Publications
The "muscle-bone unit" in children and adolescents: a 2000 overview
In former views hormones, calcium, vitamin D and other humoral and nonmechanical agents dominated control of postnatal bone strength (and "mass") in children and adolescents. However later evidence that led to weiter...
Author: Frost HM, Schönau E
Source: J Pediatr Endocrinol Metab., 2000; 13(6): 571-90, PMID: 10905381
Doc-ID: 1027,
Scientific Publications
Author: P.Schneider, W. Börner
Source: Osteoporosis, 1990; 59: 921-924
Doc-ID: 974,
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Scientific Publications
(English) Between May 1990 and February 1991 we enrolled 212 patients of 410 referred to our clinic for bone mass evaluation according to different diagnosis or therapeutic procedures. These patients were divi weiter...
Author: P. Schneider, W. Börner, J. Rendl, C. Eilles, K. Schlißke, M. Scheubeck
Source: Z Orthop (1992) 130: 16-21, 1992; 130: 16-21
Doc-ID: 975,
Scientific Publications
CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts
Fusion of macrophages is an essential step in the differentiation of osteoclasts, which play a central role in the development and remodeling of bone. Osteoclasts are important mediators of bone loss, which lea weiter...
Author: Cui W, Cuartas E, Ke J, Zhang Q, Einarsson HB, Sedgwick JD, Li J, Vignery A
Source: Proc Natl Acad Sci U S A., 2007; 104(36): 14436-41, PMID: 17726108
Doc-ID: 959,
Scientific Publications
Source: Acta Orthop Scand, 2002; Suppl 303) 43:: 44 - 52
Doc-ID: 864,
More information: Original Article
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Scientific Publications
Osteoporosis is a common multifactorial disorder of reduced bone mass. The disorder in its most common form is generalized, affecting the elderly, both sexes, and all racial groups. Multiple environmental facto weiter...
Author: Peacock M, Turner CH, Econs MJ, Foroud T
Source: Endocr Rev., 2002; 23(3): 303-26, PMID: 12050122
Doc-ID: 724,
Scientific Publications
The primary findings and conclusions of the present series of studies can be summarised as follows: I Studies I and II demonstrated that long-term racquet sports training had increased bone mineral mass and weiter...
Author: Kontulainen S
Source: Disseration, 2002;
Keywords: Bone Training
Doc-ID: 671,
More information: Original Article
Scientific Publications
Author: Schönau E, Rauch F,
Source: Hufeland-Preis Jury, 2002;
Doc-ID: 634,
Scientific Publications
A 2003 update of bone physiology and Wolff"s Law for clinicians
By 1892, Julius Wolff and others realized that mechanical loads can affect bone architecture in living beings, but the mechanisms responsible for this effect were unknown, and it had no known clinical applicati weiter...
Author: Frost HM
Source: Angle Orthod., 2004; 74(1): 3-15, PMID: 15038485
Doc-ID: 587,
More information: Original Article
Scientific Publications
Vibration exercise makes your muscles and bones stronger: fact or fiction
Vibration transmitted to the whole body or part of it has been extensively studied in relation to the risks to the health and safety of workers. These studies have highlighted the particular danger of lower-bac weiter...
Author: Cardinale M, Rittweger J
Source: J Br Menopause Soc., 2006; 12(1): 12-8, PMID: 16513017
Doc-ID: 572,
Scientific Publications
Low cost of locomotion in the banded Gecko: a test of the nocturnality hypothesis
This study tested the hypothesis that there has been an evolutionary increase in locomotor performance capacity at low temperature in nocturnal lizards. Nocturnal lizards are often active at low and suboptimal weiter...
Author: Autumn K, Farley CT, Emshwiller M, Full RJ
Source: Physiol Zool., 1997; 70(6): 660-9, PMID: 9361140
Doc-ID: 95,
Scientific Publications
Maximum speed and mechanical power output in lizards
The goal of the present study was to test the hypothesis that maximum running speed is limited by how much mechanical power the muscular system can produce. To test this hypothesis, two species of lizards, Cole weiter...
Author: Farley CT
Source: J Exp Biol., 1997; 200(Pt 16): 2189-95, PMID: 9286100
Doc-ID: 96,
Scientific Publications
Mechanism of leg stiffness adjustment for hopping on surfaces of different stiffnesses
When humans hop in place or run forward, leg stiffness is increased to offset reductions in surface stiffness, allowing the global kinematics and mechanics to remain the same on all surfaces. The purpose of the weiter...
Author: Farley CT, Houdijk HH, Van Strien C, Louie M
Source: J Appl Physiol., 1998; 85(3): 1044-55, PMID: 9729582
Doc-ID: 98,
Scientific Publications
Minimizing center of mass vertical movement increases metabolic cost in walking
A human walker vaults up and over each stance limb like an inverted pendulum. This similarity suggests that the vertical motion of a walker"s center of mass reduces metabolic cost by providing a mechanism for p weiter...
Author: Ortega JD, Farley CT
Source: J Appl Physiol., 2005; 99(6): 2099-107, PMID: 16051716
Doc-ID: 99,
Scientific Publications
Muscle mechanical advantage of human walking and running: implications for energy cost
Muscular forces generated during locomotion depend on an animal"s speed, gait, and size and underlie the energy demand to power locomotion. Changes in limb posture affect muscle forces by altering the mechanica weiter...
Author: Biewener AA, Farley CT, Roberts TJ, Temaner M
Source: J Appl Physiol., 2004; 97(6): 2266-74, PMID: 15258124
Doc-ID: 100,
Scientific Publications
Mechanics of locomotion in lizards
Lizards bend their trunks laterally with each step of locomotion and, as a result, their locomotion appears to be fundamentally different from mammalian locomotion. The goal of the present study was to determin weiter...
Author: Farley CT, Ko TC
Source: J Exp Biol., 1997; 200(Pt 16): 2177-88, PMID: 9286099
Doc-ID: 97,
Scientific Publications
When four-legged animals want to move quickly they gallop -- a gait that was thought to have no equivalent in humans. But a new paper shows that skipping in humans is biomechanically similar to galloping. In bo weiter...
Author: Farley CT
Source: Nature., 1998; 394(6695): 721-3
Doc-ID: 94,
Scientific Publications
Leg stiffness primarily depends on ankle stiffness during human hopping
When humans hop in place or run forward, they adjust leg stiffness to accommodate changes in stride frequency or surface stiffness. The goal of the present study was to determine the mechanisms by which humans weiter...
Author: Farley CT, Morgenroth DC
Source: J Biomech., 1999; 32(3): 267-73, PMID: 10093026
Doc-ID: 93,
Scientific Publications
Leg stiffness and stride frequency in human running
When humans and other mammals run, the body"s complex system of muscle, tendon and ligament springs behaves like a single linear spring ("leg spring"). A simple spring-mass model, consisting of a single linear weiter...
Author: Farley CT, González O
Source: J Biomech., 1996; 29(2): 181-6, PMID: 8849811
Doc-ID: 92,
Scientific Publications
Human hopping on damped surfaces: strategies for adjusting leg mechanics
Fast-moving legged animals bounce along the ground with spring-like legs and agilely traverse variable terrain. Previous research has shown that hopping and running humans maintain the same bouncing movement of weiter...
Author: Moritz CT, Farley CT
Source: Proc Biol Sci., 2003; 270(1525): 1741-6, PMID: 12965003
Doc-ID: 87,
Scientific Publications
During hopping in place and running, humans maintain similar center of mass dynamics by precisely adjusting leg mechanics to compensate for moderate changes in surface stiffness. We investigated the limits of t weiter...
Author: Moritz CT, Farley CT
Source: J Exp Biol., 2005; 208(Pt 5): 939-49, PMID: 15755892
Doc-ID: 88,
Scientific Publications
Independent metabolic costs of supporting body weight and accelerating body mass during walking
The metabolic cost of walking is determined by many mechanical tasks, but the individual contribution of each task remains unclear. We hypothesized that the force generated to support body weight and the work p weiter...
Author: Grabowski A, Farley CT, Kram R
Source: J Appl Physiol., 2005; 98(2): 579-83, PMID: 15649878
Doc-ID: 89,
Scientific Publications
Individual limb work does not explain the greater metabolic cost of walking in elderly adults
Elderly adults consume more metabolic energy during walking than young adults. Our study tested the hypothesis that elderly adults consume more metabolic energy during walking than young adults because they per weiter...
Author: Ortega JD, Farley CT
Source: J Appl Physiol., 2007; 102(6): 2266-73, PMID: 17363623
Doc-ID: 90,
Scientific Publications
Interaction of leg stiffness and surfaces stiffness during human hopping
When mammals run, the overall musculoskeletal system behaves as a single linear "leg spring". We used force platform and kinematic measurements to determine whether leg spring stiffness (k(leg)) is adjusted to weiter...
Author: Ferris DP, Farley CT
Source: J Appl Physiol., 1997; 82(1): 15-22; discussion 13, PMID: 9029193
Doc-ID: 91,
Scientific Publications
Human hoppers compensate for simultaneous changes in surface compression and damping
On a range of elastic and damped surfaces, human hoppers and runners adjust leg mechanics to maintain similar spring-like mechanics of the leg and surface combination. In a previous study of adaptations to damp weiter...
Author: Moritz CT, Farley CT
Source: J Biomech., 2006; 39(6): 1030-8, PMID: 16549093
Doc-ID: 86,
Scientific Publications
How animals move: an integrative view
Recent advances in integrative studies of locomotion have revealed several general principles. Energy storage and exchange mechanisms discovered in walking and running bipeds apply to multilegged locomotion and weiter...
Author: Dickinson MH, Farley CT, Full RJ, Koehl MA, Kram R, Lehman S
Source: Science., 2000; 288(5463): 100-6, PMID: 10753108
Doc-ID: 85,
Scientific Publications
Regulation of stiffness by skeletomotor reflexes
Since the early 1950s when Merton introduced his "follow-up serco hypothesis" of movement control, the dominant optinion has held that strech and unloading reflexes function to control the length of a muscle in weiter...
Author: Houk JC
Source: Annu Rev Physiol., 1979; 41: 99-114
Doc-ID: 84,
More information: Original Article
Scientific Publications
Hopping frequency in humans: a test of how springs set stride frequency in bouncing gaits
The storage and recovery of elastic energy in muscle-tendon springs is important in running, hopping, trotting, and galloping. We hypothesized that animals select the stride frequency at which they behave most weiter...
Author: Farley CT, Blickhan R, Saito J, Taylor CR
Source: J Appl Physiol., 1991; 71(6): 2127-32, PMID: 1778902
Doc-ID: 83,
Scientific Publications
Determinants of the center of mass trajectory in human walking and running
Walking is often modeled as an inverted pendulum system in which the center of mass vaults over the rigid stance limb. Running is modeled as a simple spring-mass system in which the center of mass bounces along weiter...
Author: Lee CR, Farley CT
Source: J Exp Biol., 1998; 201(Pt 21): 2935-44, PMID: 9866878
Doc-ID: 82,
Scientific Publications
Energetics of walking and running: insights from simulated reduced-gravity experiments
On Earth, a person uses about one-half as much energy to walk a mile as to run a mile. On another planet with lower gravity, would walking still be more economical than running? When people carry weights while weiter...
Author: Farley CT, McMahon TA
Source: J Appl Physiol., 1992; 73(6): 2709-12, PMID: 1490989
Doc-ID: 81,
Scientific Publications
Energetics and mechanics of human running on surfaces of different stiffnesses
Mammals use the elastic components in their legs (principally tendons, ligaments, and muscles) to run economically, while maintaining consistent support mechanics across various surfaces. To examine how leg sti weiter...
Author: Kerdok AE, Biewener AA, McMahon TA, Weyand PG, Herr HM
Source: J Appl Physiol., 2002; 92(2): 469-78, PMID: 11796653
Doc-ID: 80,
Scientific Publications
Biomechanics of walking and running: center of mass movements to muscle action
Author: Farley CT, Ferris DP
Source: Exerc Sport Sci Rev., 1998; 26: 253-85, PMID: 9696992
Doc-ID: 79,
More information: Original Article
Scientific Publications
Walking involves a cyclic exchange of gravitational potential energy and kinetic energy of the center of mass. Our goal was to understand how the limbs of walking quadrupeds coordinate the vertical movements of weiter...
Author: Griffin TM, Main RP, Farley CT
Source: J Exp Biol., 2004; 207(Pt 20): 3545-58, PMID: 15339951
Doc-ID: 78,
Scientific Publications
Athletic footwear, leg stiffness, and running kinematics
CONTEXT: The leg acts as a linear spring during running and hopping and adapts to the stiffness of the surface, maintaining constant total stiffness of the leg-surface system. Introducing a substance (eg, footw weiter...
Author: Bishop M, Fiolkowski P, Conrad B, Brunt D, Horodyski M
Source: J Athl Train., 2006; 41(4): 387-92, PMID: 17273463
Doc-ID: 77,
Scientific Publications
A mechanical trigger for the trot-gallop transition in horses
It is widely thought that animals switch gaits at speeds that minimize energetic cost. Horses naturally switched from a trot to a gallop at a speed where galloping required more energy than trotting, and thus, weiter...
Author: Farley CT, Taylor CR
Source: Science., 1991; 253(5017): 306-8, PMID: 1857965
Doc-ID: 76,
Scientific Publications
Differential shock transmission response of the human body to impact severity and lower limb posture
The shocks imparted to the foot during locomotion may lead to joint-degenerative diseases and jeopardize the visual-vestibular functions. The body relies upon several mechanisms and structures that have unique weiter...
Author: Lafortune MA, Lake MJ, Hennig EM
Source: J Biomech, 1996; 29(12): 1531-7, PMID: 8945651
Doc-ID: 29,
Scientific Publications
What is new in neuro-musculoskeletal interactions: Neuromuscular Science
Author: Rittweger J, Rauch F
Source: J Musculoskelet Neuronal Interact., 2002; 2(2): 177-80, PMID: 15758468
Keywords: Mechanostat
Doc-ID: 356,
More information: Original Article
Scientific Publications
Author: Frost HM
Source: Bone., 1997; 20(3): 183-9, PMID: 9071467
Keywords: Mechanostat
Doc-ID: 288,
Scientific Publications
Defining osteopenias and osteoporoses: another view (with insights from a new paradigm)
This article suggests classifying "osteoporoses" by their biomechanical pathogenesis instead of by their severity or their accompanying medical conditions. (A) In a "true osteoporosis," bone fragility would inc weiter...
Author: Frost HM
Source: Bone., 1997; 20(5): 385-91, PMID: 9145234
Keywords: Mechanostat
Doc-ID: 289,
Scientific Publications
High-frequency vibration training increases muscle power in postmenopausal women
OBJECTIVE: To test whether training on a high-frequency (28Hz) vibrating platform improves muscle power and bone characteristics in postmenopausal women. DESIGN: Randomized controlled trial with 6-month follow- weiter...
Author: Russo CR, Lauretani F, Bandinelli S, Bartali B, Cavazzini C, Guralnik JM, Ferrucci L
Source: Arch Phys Med Rehabil., 2003; 84(12): 1854-7, PMID: 14669194
Doc-ID: 274,
Scientific Publications
Predictors of falls among elderly people. Results of two population-based studies
A study was performed to identify and rank risk factors for falling among populations of institutionalized (fallers, N = 79, nonfallers, N = 70) and noninstitutionalized (fallers, N = 34, nonfallers, N = 34) el weiter...
Author: Robbins AS, Rubenstein LZ, Josephson KR, Schulman BL, Osterweil D, Fine G
Source: Arch Intern Med., 1989; 149(7): 1628-33, PMID: 2742437
Doc-ID: 55,
Scientific Publications
Risk factors for recurrent nonsyncopal falls. A prospective study
Falls are a major threat to the health of older persons. We evaluated potential risk factors for falls in 325 community-dwelling persons aged 60 years or older who had fallen during the previous year, then foll weiter...
Author: Nevitt MC, Cummings SR, Kidd S, Black D
Source: JAMA., 1989; 261(18): 2663-8, PMID: 2709546
Doc-ID: 53,
Scientific Publications
Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group
BACKGROUND. Many risk factors for hip fractures have been suggested but have not been evaluated in a comprehensive prospective study. METHODS. We assessed potential risk factors, including bone mass, in 9516 wh weiter...
Author: Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, Cauley J, Black D, Vogt TM
Source: N Engl J Med., 1995; 332(12): 767-73, PMID: 7862179
Doc-ID: 52,
Scientific Publications
Neue Erkenntnisse über den Zusammenhang zwischen Knochenstabilität und Muskelkraft
Author: Schiessl H, Willnecker J
Source: TraumaLinc, 2000; 1:
Keywords: Mechanostat, Muscle-Bone Unit
Doc-ID: 190,
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Scientific Publications
Die Muskeln als Determinate des erfolgreichen Alterns
Author: Runge M
Source: MedReport, 2003; 13: 12-13
Doc-ID: 254,
Scientific Publications
Prevention of falls in the elderly trial (PROFET): a randomised controlled trial
BACKGROUND: Falls in elderly people are a common presenting complaint to accident and emergency departments. Current practice commonly focuses on the injury, with little systematic assessment of the underlying weiter...
Author: Close J, Ellis M, Hooper R, Glucksman E, Jackson S, Swift C
Source: Lancet., 1999; 353(9147): 93-7, PMID: 10023893
Doc-ID: 109,
Scientific Publications
Neuromechanical adaptation to hopping with an elastic ankle-foot orthosis
When humans hop or run on different surfaces, they adjust their effective leg stiffness to offset changes in surface stiffness. As a result, the overall stiffness of the leg-surface series combination remains i weiter...
Author: Ferris DP, Bohra ZA, Lukos JR, Kinnaird CR
Source: J Appl Physiol., 2006; 100(1): 163-70, PMID: 16179395
Doc-ID: 101,
Scientific Publications
Neuromuscular changes for hopping on a range of damped surfaces
Humans hopping and running on elastic and damped surfaces maintain similar center-of-mass dynamics by adjusting stance leg mechanics. We tested the hypothesis that the leg transitions from acting like an energy weiter...
Author: Moritz CT, Greene SM, Farley CT
Source: J Appl Physiol., 2004; 96(5): 1996-2004, PMID: 14688034
Doc-ID: 102,
Scientific Publications
Passive dynamics change leg mechanics for an unexpected surface during human hopping
Humans running and hopping maintain similar center-of-mass motions, despite large changes in surface stiffness and damping. The goal of this study was to determine the contributions of anticipation and reaction weiter...
Author: Moritz CT, Farley CT
Source: J Appl Physiol., 2004; 97(4): 1313-22, PMID: 15169748
Doc-ID: 103,
Scientific Publications
Runners adjust leg stiffness for their first step on a new running surface
Human runners adjust the stiffness of their stance leg to accommodate surface stiffness during steady state running. This adjustment allows runners to maintain similar center of mass movement (e.g., ground cont weiter...
Author: Ferris DP, Liang K, Farley CT
Source: J Biomech., 1999; 32(8): 787-94, PMID: 10433420
Doc-ID: 104,
Scientific Publications
Running in the real world: adjusting leg stiffness for different surfaces
A running animal coordinates the actions of many muscles, tendons, and ligaments in its leg so that the overall leg behaves like a single mechanical spring during ground contact. Experimental observations have weiter...
Author: Ferris DP, Louie M, Farley CT
Source: Proc Biol Sci., 1998; 265(1400): 989-94, PMID: 9675909
Doc-ID: 105,
Scientific Publications
Running springs: speed and animal size
Trotting and hopping animals use muscles, tendons and ligaments to store and return elastic energy as they bounce along the ground. We examine how the musculoskeletal spring system operates at different speeds weiter...
Author: Farley CT, Glasheen J, McMahon TA
Source: J Exp Biol., 1993; 185: 71-86, PMID: 8294853
Doc-ID: 106,
Scientific Publications
Soleus H-reflex gain in humans walking and running under simulated reduced gravity
The Hoffmann (H-) reflex is an electrical analogue of the monosynaptic stretch reflex, elicited by bypassing the muscle spindle and directly stimulating the afferent nerve. Studying H-reflex modulation provides weiter...
Author: Ferris DP, Aagaard P, Simonsen EB, Farley CT, Dyhre-Poulsen P
Source: J Physiol., 2001; 530(Pt 1): 167-80, PMID: 11136869
Doc-ID: 107,
Scientific Publications
Impact of muscle power and force on gait speed in disabled older men and women
BACKGROUND: The purpose of this study was to explore the relationship between muscle power output at different external resistances and performance of functional tasks. The authors hypothesized that power at 40 weiter...
Author: Cuoco A, Callahan DM, Sayers S, Frontera WR, Bean J, Fielding RA
Source: J Gerontol A Biol Sci Med Sci., 2004; 59(11): 1200-6, PMID: 15602076
Doc-ID: 108,
Scientific Publications
OBJECTIVE: To evaluate the effects of two exercise approaches, Tai Chi (TC) and computerized balance training (BT), on specified primary outcomes (biomedical, functional, and psychosocial indicators of frailty) weiter...
Author: Wolf SL, Barnhart HX, Kutner NG, McNeely E, Coogler C, Xu T
Source: J Am Geriatr Soc., 1996; 44(5): 489-97, PMID: 8617895
Doc-ID: 54,
Scientific Publications
Wie geht es weiter mit der Messung der Knochendichte
Author: Semler J
Source: Mobiles Leben, 2000; 7: 7-9
Doc-ID: 17,

