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Bone, 1995; 17(4 Suppl): 353S-364S, PMID: 8579938

Perspectives of pQCT technology associated to biomechanical studies in skeletal research employing rat models

Jahr: 1995

Ferretti JL
CEMFoC-CIUNR-CONICET, National University of Rosario, Argentina.


Assessment of bone material quality and architectural indicators by means of peripheral quantitative computed tomography (pQCT) offers a wide perspective for skeletal research employing noninvasive procedures. Some mechanically-validated examples of these pQCT applications in animal models are described. They concern (a) the analysis of bone mechanostatical interrelationships as shown by experimental "distribution/quality" curves, and (b) the noninvasive determination of bone strength. An attractive attempt to extrapolate the latter to human bone studies is also discussed.

GID: 13; Letzte Änderung: 23.11.2007