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J Musculoskelet Neuronal Interact., 2004; 4(1): 105-8, PMID: 15615084

Muscle mass during childhood--relationship to skeletal development

Year: 2004

Schoenau E, Neu MC, Manz F
Childrens Hospital, University of Cologne, Germany.


Bone densitometric data often are difficult to interpret in children and adolescents because of large inter- and intraindividual variations in bone size. Here, we propose a functional approach to bone densitometry that addresses two questions: Is bone strength normally adapted to the largest physiological loads, that is, muscle force? Is muscle force adequate for body size? To implement this approach, forearm muscle cross-sectional area (CSA) and bone mineral content (BMC) of the radial diaphysis were measured in 349 healthy subjects from 6 to 19 years of age (183 girls), using peripheral quantitative computed tomography (pQCT). This functional approach to pediatric bone densitometric data should be adaptable to a variety of densitometric techniques.

GID: 1852; Last update: 27.07.2009
More information: Original Article