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J Musculoskelet Neuronal Interact., 2009; 9(4): 256-62, PMID: 19949283

Age comparisons of bone density and geometry in men

Year: 2009

Sherk VD, Karabulut M, Bemben MG, Bemben DA
Bone Density Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman Oklahoma, 73019, USA.


Objectives: The purposes of this study were to examine tibia bone density and geometry in young and middle aged men, and to explore relationships between pQCT- and DXA-derived body composition variables. Methods: Healthy males (18-30 years old, n=31; 50-64 years old, n=37) had their total body areal bone mineral density (aBMD) and body composition measured with Dual Energy X-ray Absorptiometry (DXA). Volumetric bone characteristics, muscle cross-sectional area (MCSA) and fat cross-sectional area (FCSA) of the leg were measured with peripheral Quantitative Computed Tomography (pQCT). Results: Young men were significantly (p<0.05) lighter and had less fat mass than older men. Total volumetric BMD (vBMD) at 66% of the tibia length was significantly lower (p<0.05) in older men. Bone-free lean body mass values were useful predictors of total and cortical area and content (R(2)=0.338-0.467). MCSA was more predictive of leg BFLBM than total body BFLBM, and those relationships were stronger in older men. Conclusions: Differences in tibial bone area and density existed between young and middle-aged men, and relationships between pQCT- and DXA-derived body composition variables were age-dependent.

GID: 2086; Last update: 03.12.2009
More information: Original Article