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Int J Obes (Lond), 2014; 38(11): 1478-80, PMID: 24522244

Preferential deposition of visceral adipose tissue occurs due to physical inactivity.

Year: 2014

Belavy DL, Mohlig M, Pfeiffer AF, Felsenberg D, Armbrecht G
Charite Universitatsmedizin Berlin, Center of Muscle and Bone Research, Berlin, Germany.


We hypothesized that strict inactivity (bed-rest) would lead to regional differences in fat deposition. Twenty-four male subjects underwent 60d bed-rest and remained inactive (n=9), performed resistance exercise plus whole-body vibration (RVE; n=7) or resistance exercise only (RE; n=8). Fat mass was assessed via dual X-ray absorptiometry. In the inactive subjects, fat deposition differed between body regions (P=0.0005) with android region visceral adipose tissue increasing the most (+29% at end bed-rest), followed by remainder of the trunk (from chin to the iliac crest; +10%) and the arms and legs (both +7%). Insulin sensitivity reduced in the inactive subjects at the end of bed-rest (P=0.036). RE did not have a significant impact on regional fat mass changes (P>/=0.055). In RVE, increases in visceral adipose tissue (-14% P=0.028 versus inactive subjects) and in the arms (arms -8%, P=0.011 versus inactive) were not seen. We conclude that inactivity leads to a preferential increase in visceral adipose tissue.International Journal of Obesity accepted article preview online, 13 February 2014; doi:10.1038/ijo.2014.26.

Keywords: Reduction of Fat / Adipose tissue, visceral adipose tissue
GID: 3479; Last update: 20.02.2014