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J Musculoskelet Neuronal Interact, 2015; 15(2): 171-6, PMID: 26032209

Physical activity in youth with osteogenesis imperfecta type I.

Year: 2015

Pouliot-Laforte A, Veilleux LN, Rauch F, Lemay M
Shriners Hospital for Children and Departement of Pediatrics, McGill University, 1529 avenue Cedar, Montreal, Quebec, Canada H3G 1A6.


INTRODUCTION: Individuals with Osteogenesis Imperfecta (OI) type I often show muscular weakness. However, it is unclear whether muscular weakness is a consequence of physical inactivity or a result of the disease itself. The aim was to assess muscle function in youth with OI type I and evaluate physical activity (PA). METHODS: Fourteen children with OI type I (mean age [SD]: 12.75 [4.62] years) were compared to 14 age- and gender-matched controls (mean age [SD]: 12.75 [4.59] years). Muscle force and power were determined through mechanography. PA and daily energy expenditure were measured with an accelerometer and a questionnaire. RESULTS: Compared to controls, children with OI type I had lower muscle force and power. OI type I children were as active as their healthy counterparts. CONCLUSIONS: Children and adolescents with OI type I and their healthy counterparts did not reached daily recommendations of PA. Given their muscle function deficit, youth with OI type I would benefit to reach these recommendations to prevent precocious effect of aging on muscles.

GID: 3924; Last update: 17.06.2015
More information: Original Article