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J Musculoskelet Neuronal Interact, 2014; 14(3): 294-302, PMID: 25198224

Feasibility, compliance, and efficacy of a randomized controlled trial using vibration in pre-pubertal children.

Year: 2014

Binkley TL, Parupsky EC, Kleinsasser BA, Weidauer LA, Specker BL
Ethel Austin Martin Program in Human Nutrition, South Dakota State University, United States.


OBJECTIVE: Interventions utilizing vibration may increase bone mass and size which may reduce forearm fractures in children. This randomized controlled pilot trial tested the feasibility, compliance and efficacy of forearm loading regimes in an after-school program in pre-pubertal children aged 6-10 years. METHODS: A 12-week randomized controlled trial incorporated high (HMMS; N=10) and low (LMMS; N=10) magnitude mechanical stimulation vibration, floor exercises (N=9), and controls (N=10). Radial bone measures by DXA and pQCT were compared at the end of intervention (12-weeks) and 4-months post-intervention (4-months post). RESULTS: Percent changes were significantly greater in floor vs. control for ultra-distal areal BMD by DXA at 12-weeks (1%[-2,5] vs.-5%[-8,-2] respectively, p=0.02) and 4-months post (5%[1,8] vs -2%[-5,2], p=0.03) and in HMMS vs. controls for trabecular vBMD by pQCT at 12-weeks (4%[0, 8], vs. -8% [-14, -2], p=0.02). Children exposed to HMMS showed positive changes in cortical BMC, area, and cortical vBMD after 12 weeks that remained 4 months post-intervention. Children exposed to floor exercise showed positive changes in cortical BMC, area, and periosteal circumference 4-months post-intervention. Controls had decreased trabecular BMD, but increased bone area and periosteal circumference. CONCLUSIONS: Exposure to floor exercise and HMMS increased trabecular aBMD and vBMD in the radius.

Keywords: BMC, BMD, High-intensity Vibration, Low-intensity Vibration, DXA, pQCT
GID: 3632; Last update: 16.09.2014