Scientific publications for the application area muscle and bone
Here you will find all scientific publications, listed by date of last update. This category currently includes 194 entries.
Literature (194)
Scientific Publications (2023)
Sex estimation is a key element in the analysis of unknown skeletal remains. The vertebrae display clear sex discrepancy and have proven accurate in conventional morphometric sex estimation. This proof-of-con weiter...
Author: Oura P, Korpinen N, Machnicki AL, Junno JA
Source: Forensic Sci Med Pathol, 2023; (): , PMID: 36773213
GID: 5903; Last update: 13.02.2023
Scientific Publications (2023)
Sex- and site-specific, age-related changes in bone density - a Terry collection study.
As modern populations are living longer, age-related health issues have become more common. One growing concern is the age-related bone density loss that increases the individual"s risk for fractures, which u weiter...
Author: Korpinen N, Oura P, Junno JA
Source: Homo, 2023; (): , PMID: 36752669
GID: 5905; Last update: 13.02.2023
Scientific Publications (2006)
Subjective ratings of whole-body vibration for single- and multi-axis motion
The purpose of this research is to explore the use of whole-body vibration platforms commercially available in the health and sports sector. Experiments were conducted using two platforms providing a sinusoidal weiter...
Author: Heather Corrie, Neil J Mansfield, Katherine Brooke-Wavell
Source: 41st United Kingdom Group Meeting on Human Responses to Vibration, 2006; 41:
GID: 5889; Last update: 27.01.2023
Scientific Publications (2022)
Osteoporosis in children and adolescents: how to treat and monitor?
Osteoporosis is a condition of increased bone fragility associated with fractures. Apart from primary genetic osteoporotic conditions, secondary osteoporosis in children is being increasingly recognized. As a weiter...
Author: Ciancia S, Hogler W, Sakkers RJB, Appelman-Dijkstra NM, Boot AM, Sas TCJ, Renes JS
Source: Eur J Pediatr, 2022; (): , PMID: 36472650
GID: 5862; Last update: 13.12.2022
Scientific Publications (2021)
An update on methods for assessing bone quality and health in Cystic fibrosis.
With increasing life expectancy in people with Cystic fibrosis (CF), the focus of clinical care has shifted to management and prevention of non-pulmonary comorbidities. CF related bone disease, defined by low b weiter...
Author: Williams KM, Darukhanavala A, Hicks R, Kelly A
Source: J Clin Transl Endocrinol, 2021; 27(): 100281, PMID: 34984171
GID: 5621; Last update: 10.01.2022
Scientific Publications (2021)
PURPOSE: The assessment of body composition is an integral part in diagnosing sarcopenia. The purpose of this study was to determine the relationships between peripheral quantitative computed tomography (pQCT) weiter...
Author: Martini S, Petermeise S, Henkel M, Weiss S, Schaupp A, Ferrari U, Schmidmaier R, Drey M
Source: Arch Gerontol Geriatr, 2021; 97(): 104512, PMID: 34481136
GID: 5542; Last update: 07.09.2021
Scientific Publications (1910)
Author: P Hoffmann
Source: Arch Anat Physiol., 1910; 1: 223–246.
GID: 5540; Last update: 02.09.2021
Scientific Publications (2013)
Osteogenesis imperfecta: Neues zur Pathogenese und Therapie Zertifizierte Fortbildung
Author: Heike Hoyer-Kuhn, Oliver Semler
Source: pädiatrie hautnah, 2013; 25(1): 28-34
GID: 5518; Last update: 27.07.2021
Scientific Publications (2020)
Hintergrund: Zahlreiche wissenschaftliche Studien deuten auf positive trainingstherapeutische Effekte bei Patienten mit interstitiellen Lungenerkrankungen (ILD ) hin. Patienten profitieren von einem positiven E weiter...
Author: J Kölpin
Source: Dissertation, 2020;
GID: 5392; Last update: 29.04.2021
Scientific Publications (2021)
Vertical jumping power declines with advancing age, which is theoretically explicable by loss of muscle mass and increases in body fat. However, the results of previous cross-sectional studies remain inconsiste weiter...
Author: Alvero-Cruz JR, Brikis M, Chilibeck P, Frings-Meuthen P, Vico Guzman JF, Mittag U, Michely S, Mulder E, Tanaka H, Tank J, Rittweger J
Source: Front Physiol, 2021; 12(): 643649, PMID: 33868010
GID: 5393; Last update: 29.04.2021
Scientific Publications (2020)
Knochenmasseverlust durch muskuläre Entlastung und Immobilisation
Der Knochen ist ein vitales Gewebe, das sich ständig an die Notwendigkeiten der vorliegenden Lebensbedingungen anpasst und mit vielen Stoffwechselprozessen interagiert. Von dem Gedanken, dass der Knochen reine weiter...
Author: Dieter Felsenberg, Franz Jakob
Source: Osteologie, 2020; 29: 123-131
GID: 5297; Last update: 09.02.2021
Scientific Publications (2020)
BACKGROUND: Most infants born extremely preterm (EP; <28 weeks" gestation) or extremely low birthweight (ELBW; <1000 g birthweight) in the post surfactant era (early 1990s) are now surviving into adulthood. Pr weiter...
Author: Haikerwal A, Doyle LW, Patton G, Garland SM, Cheung MM, Wark JD, Cheong JLY
Source: Bone, 2020; 143(): 115648, PMID: 32950698
GID: 5283; Last update: 02.02.2021
Scientific Publications (2009)
Bone volumetric density, geometry, and strength in female and male collegiate runners.
PURPOSE: To explore differences in tibial bone geometry, volumetric density, and estimates of bone strength in runners and healthy controls. METHODS: Male (n = 21) and female (n = 38) runners (49.1 +/- 13.2 mi weiter...
Author: Smock AJ, Hughes JM, Popp KL, Wetzsteon RJ, Stovitz SD, Kaufman BC, Kurzer MS, Petit MA
Source: Med Sci Sports Exerc, 2009; 41(11): 2026-32, PMID: 19812515
GID: 5272; Last update: 18.01.2021
Scientific Publications (2020)
BACKGROUND: Whole-body vibration (WBV) is a method utilizing vibrating platforms to expose individuals to mechanical vibration. In its various applications, it has been linked to improved muscular, skeletal, m weiter...
Author: Wuestefeld A, Fuermaier ABM, Bernardo-Filho M, da Cunha de Sa-Caputo D, Rittweger J, Schoenau E, Stark C, Marin PJ, Seixas A, Judex S, Taiar R, Nyakas C, van der Zee EA, van Heuvelen MJG, Tucha O
Source: PLoS One, 2020; 15(7): e0235905, PMID: 32697809
Keywords: Reporting Guidelines
GID: 5252; Last update: 13.12.2020
More information: Original Article
Scientific Publications (2020)
Analysis of low-dose estrogen on callus BMD as measured by pQCT in postmenopausal women.
BACKGROUND: Osteoporosis affects elderly patients of both sexes. It is characterized by an increased fracture risk due to defective remodeling of the bone microarchitecture. It affects in particular postmenopau weiter...
Author: Jackle K, Kolb JP, Schilling AF, Schlickewei C, Amling M, Rueger JM, Lehmann W
Source: BMC Musculoskelet Disord, 2020; 21(1): 693, PMID: 33076902
GID: 5212; Last update: 26.10.2020
Scientific Publications (2020)
Prophylactic oophorectomy is recommended for women at high risk for ovarian cancer, but the associated impact on bone health is of clinical concern. This prospective, controlled study demonstrated substantial l weiter...
Author: Jiang H, Robinson DL, Lee PVS, Krejany EO, Yates CJ, Hickey M, Wark JD
Source: Osteoporos Int, 2020; (): , PMID: 32856124
Keywords: DXA . Finite element analysis . Hormone replacement . pQCT . Surgical menopause
GID: 5186; Last update: 31.08.2020
Scientific Publications (2020)
Total urinary polyphenols and longitudinal changes of bone properties. The InCHIANTI study.
The aim of this study was to evaluate the association of levels of urinary total polyphenols considered as a proxy measure of polyphenol intake, with longitudinal changes of bone properties, in the InCHIANTI s weiter...
Author: Di Iorio A, Abate M, Bandinelli S, Barassi G, Cherubini A, Andres-Lacueva C, Zamora-Ros R, Paganelli R, Volpato S, Ferrucci L
Source: Osteoporos Int, 2020; (): , PMID: 32793995
GID: 5179; Last update: 25.08.2020
Scientific Publications (2020)
Serum calcium (Ca), bone biomarkers and radiological imaging do not allow accurate evaluation of bone mineral balance (BMB), a key determinant of bone mineral density (BMD) and fracture risk. We studied natural weiter...
Author: Shroff R, Fewtrell M, Heuser A, Kolevica A, Lalayiannis A, McAlister L, Silva S, Goodman N, Schmitt CP, Biassoni L, Rahn A, Fischer DC, Eisenhauer A
Source: J Bone Miner Res, 2020; (): , PMID: 32786145
GID: 5181; Last update: 25.08.2020
Scientific Publications (2020)
Sarcopenia is a clinical condition mainly affecting the elderly that can be associated in a long run with severe consequences like malnutrition and frailty. Considering the progressive ageing of the world popu weiter...
Author: Giraudo C, Cavaliere A, Lupi A, Guglielmi G, Quaia E
Source: Quant Imaging Med Surg, 2020; 10(8): 1602-1613, PMID: 32742955
GID: 5182; Last update: 25.08.2020
Scientific Publications (2020)
INTRODUCTION: Transplantation of cancellous tissue from human femoral heads (FK) is an established method in the reconstruction of bony defects in orthopedic and trauma surgery. Standardized rating systems wi weiter...
Author: Siemssen N, Friesecke C, Wolff C, Beller G, Wassilew K, Neuner B, Schonfeld H, Pruss A
Source: Orthopade, 2020; (): , PMID: 32642941
GID: 5158; Last update: 13.07.2020
Scientific Publications (2020)
BACKGROUND: Predictors of bone deterioration after hip fracture have not been well characterized. The aim of this study was to examine the associations of physical function and lean body mass (LBM) with loss of weiter...
Author: Suominen TH, Edgren J, Salpakoski A, Kallinen M, Cervinka T, Rantalainen T, Tormakangas T, Heinonen A, Sipila S
Source: BMC Musculoskelet Disord, 2020; 21(1): 367, PMID: 32517755
Keywords: Aging, Bone mineral density, Hip fracture, Lean body mass, Physical function, pQCT
GID: 5140; Last update: 15.06.2020
Scientific Publications (2020)
Muscle-Bone Interactions in Chinese Men and Women Aged 18-35 Years.
To characterize bone mineral density (BMD), bone strength, muscle and fat mass, and muscle strength and power in Chinese women (n = 25) and men (n = 28) classified as in the bone accrual phase (18-25 years) or weiter...
Author: Su M, Chen Z, Baker B, Buchanan S, Bemben D, Bemben M
Source: J Osteoporos. 2020:8126465., 2020; PMID: 32459739
GID: 5130; Last update: 03.06.2020
Scientific Publications (2020)
Bone Densities and Bone Geometry in Children and Adolescents With Arthrogryposis
Objective: To describe bone densitometry results using lumbar spine dual-energy X-ray absorptiometry and forearm peripheral quantitative computed tomography (pQCT) in children with arthrogryposis multiplex cong weiter...
Author: Noemi Dahan-Oliel 1 , Jessica Collins 2 , Damian Rauch 2 , Gloria Bukovy 2 , Reggie Hamdy 3 , Frank Rauch 4
Source: Bone, 2020; 137: 115454, PMID: 32464275
Keywords: Arthrogryposis; Bone mineral density; Children; Fat and muscle mass.
GID: 5128; Last update: 03.06.2020
Scientific Publications (2020)
Interscholastic Athletics and Bone Strength: The Iowa Bone Development Study.
Pashkova, A, Hartman, JM, Letuchy, EM, and Janz, KF. Interscholastic athletics and bone strength: the Iowa bone development study. J Strength Cond Res XX(X): 000-000, 2020-The objective of this study was to det weiter...
Author: Pashkova A, Hartman JM, Letuchy EM, Janz KF.
Source: J Strength Cond Res. 2020 May 25;, 2020; PMID: 32459739
GID: 5129; Last update: 03.06.2020
Scientific Publications (2020)
Background: Adults with celiac disease (CeD) show low bone mineral density (BMD) and high fracture risk. CeD guidelines suggest measurements of serum minerals and vitamin D. However, studies on vitamin levels weiter...
Author: Ciacci C, Bilancio G, Russo I, Iovino P, Cavallo P, Santonicola A, Bucci C, Cirillo M, Zingone F
Source: Nutrients, 2020; 12(4): 929, PMID: 32230847
GID: 5090; Last update: 06.04.2020
Scientific Publications (2020)
Sex differences in bone density, geometry, and bone strength of competitive soccer players.
OBJECTIVES: To examine sex differences in bone characteristics in competitive soccer players. METHODS: 43 soccer players (male, n=23; female, n=20), and 43 matched controls (males, n=23; females, n=20), complet weiter...
Author: Baker BS, Chen Z, Larson RD, Bemben MG, Bemben DA
Source: J Musculoskelet Neuronal Interact, 2020; 20(1): 62-76, PMID: 32131370
GID: 5071; Last update: 10.03.2020
Scientific Publications (2020)
Deriving pQCT-Type Spatial Density from DXA Images.
INTRODUCTION: Musculoskeletal overuse injuries are a serious problem in the military, particularly in basic combat training, resulting in hundreds of millions of dollars lost because of limited duty days, medic weiter...
Author: Iyoho AE, Niederberger BA, Bergquist-Turori D, Kelly KR, Ng LJ
Source: Mil Med, 2020; 185(Supplement_1): 430-434, PMID: 32074354
GID: 5048; Last update: 24.02.2020
Scientific Publications (2019)
Vitamin D is important for normal skeletal homeostasis, especially in growing children. There are no previous genome-wide association (GWA) studies exploring genetic factors that influence vitamin D metabolism weiter...
Author: Kampe A, Enlund-Cerullo M, Valkama S, Holmlund-Suila E, Rosendahl J, Hauta-Alus H, Pekkinen M, Andersson S, Makitie O
Source: PLoS Genet, 2019; 15(12): e1008530, PMID: 31841498
GID: 5020; Last update: 14.01.2020
Scientific Publications (2019)
OBJECTIVES: The mechanical components of bone strength (size, shape and density) in adolescents with T1DM are not extensively studied. METHODS: The studied group comprises 39 adolescents, aged 11,9-18,0 yrs. weiter...
Author: Jaworski M, Wierzbicka E, Pludowski P, Szalecki M
Source: J Musculoskelet Neuronal Interact, 2019; 19(4): 435-447, PMID: 31789294
GID: 5004; Last update: 09.12.2019
Scientific Publications (2019)
Bone health, muscle properties and stretch-shortening cycle function of young and elderly males.
The aim of this study was to examine bone, muscle, strength and stretch-shortening cycle (SSC) performance in young and elderly individuals with an ankle model to elucidate potential effects of ageing that hav weiter...
Author: Rice PE, Needle AR, Leicht ZS, Zwetsloot KA, McBride JM
Source: J Musculoskelet Neuronal Interact, 2019; 19(4): 389-395, PMID: 31789290
GID: 5005; Last update: 09.12.2019
Scientific Publications (2020)
Bone health in women with a history of gestational diabetes or obesity.
INTRODUCTION: Type 2 diabetes is associated with an increased risk of bone fractures. However, bone health of women with a history of gestational diabetes (GDM) has received little attention. This cross-section weiter...
Author: Engberg E, Koivusalo SB, Huvinen E, Viljakainen H
Source: Acta Obstet Gynecol Scand, 2020; 99 (4): 477-487, PMID: 31784976
GID: 5000; Last update: 02.12.2019
Scientific Publications (2020)
Muscle and bone parameters in underprivileged Indian children and adolescents with T1DM.
BACKGROUND: The incidence of Type 1 diabetes mellitus (T1DM) is increasing and sarcopenia and osteoporosis have been reported to be associated with long standing diabetes. There is scarcity of data on bone heal weiter...
Author: Dongare-Bhor S, Lohiya N, Maheshwari A, Ekbote V, Chiplonkar S, Padidela R, Mughal Z, Khadilkar V, Khadilkar A
Source: Bone, 2020; 130: 115074, PMID: 31626994
GID: 4996; Last update: 19.11.2019
Scientific Publications (2020)
Due to limitations of the predominant clinical method for diagnosing osteoporosis, an engineering model based on a dedicated CT scanner for bone density and structure was applied in fracture patients and contro weiter...
Author: Jiang H, Robinson DL, Yates CJ, Lee PVS, Wark JD
Source: Osteoporos Int, 2020; 31(1): 141-151, PMID: 31720708
GID: 4990; Last update: 19.11.2019
Scientific Publications (2019)
In 2015, the International Society for Clinical Densitometry (ISCD) position statement regarding peripheral quantitative computed tomography (pQCT) did not recommend routine use of pQCT, in clinical settings un weiter...
Author: Cervinka T, Giangregorio L, Sievanen H, Cheung AM, Craven BC
Source: J Clin Densitom, 2019; 21(4): 563-582, PMID: 30196052
GID: 4985; Last update: 18.10.2019
Scientific Publications (2019)
Bone Mass and Strength and Fall-Related Fractures in Older Age.
Introduction: Low bone mineral density is a risk factor for fractures. The aim of this follow-up study was to assess the association of various bone properties with fall-related fractures. Materials and Methods weiter...
Author: Uusi-Rasi K, Karinkanta S, Tokola K, Kannus P, Sievanen H
Source: J Osteoporos, 2019; 2019: 5134690, PMID: 31583071
GID: 4979; Last update: 14.10.2019
Scientific Publications (2019)
Dual energy X-ray absorptiometry, the current clinical criterion method for osteoporosis diagnosis, has limitations in identifying individuals with increased fracture risk, especially at the distal radius. Peri weiter...
Author: Jiang H, Robinson DL, McDonald M, Lee PVS, Kontulainen SA, Johnston JD, Yates CJ, Wark JD
Source: Bone, 2019; 129: 115051, PMID: 31472298
GID: 4960; Last update: 02.09.2019
Scientific Publications (2020)
OBJECTIVE: This study aimed to elucidate the effects of changes in the geometry and density of the metacarpal bone of patients with rheumatoid arthritis (RA). METHODS: This prospective study included consecutiv weiter...
Author: Aeberli D, Fankhauser N, Zebaze R, Bonel H, Moller B, Villiger PM
Source: Semin Arthritis Rheum, 2020; 50(2): 220-227, PMID: 31466837
GID: 4961; Last update: 02.09.2019
Scientific Publications (2019)
Impact of Adrenal Hormone Supplementation on Bone Geometry in Growing Teens With Anorexia Nervosa.
PURPOSE: Adolescents with anorexia nervosa (AN) have decreased dehydroepiandrosterone (DHEA) and estrogen concentrations that may contribute to skeletal deficits. We sought to determine whether DHEA + estrogen weiter...
Author: DiVasta AD, Feldman HA, O"Donnell JM, Long J, Leonard MB, Gordon CM
Source: J Adolesc Health, 2019; 65(4): 462-468, PMID: 31227390
GID: 4933; Last update: 01.07.2019
Scientific Publications (2019)
Pentosidine is an advanced glycation end product (AGE) associated with fracture in adults with diabetes. AGE accumulation in bone collagen contributes to bone fragility but might also adversely influence bone t weiter...
Author: Kindler JM, Laing EM, Liu W, Dain JA, Lewis RD
Source: J Bone Miner Res, 2019; 34(8): 1446-1450, PMID: 31220375
GID: 4934; Last update: 01.07.2019
Scientific Publications (2019)
There is still limited data on the association between 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), and bone health in healthy younger adults, particularly in Latin America. This cross-sectional a weiter...
Author: Mendes MM, Hart KH, Lanham-New SA, Botelho PB
Source: Nutrients, 2019; 11(6): 1267, PMID: 31167443
GID: 4916; Last update: 17.06.2019
Scientific Publications (2019)
Androgen deprivation therapy (ADT) improves survival in men with advanced prostate cancer (PCa), but has been associated with compromised skeletal health and increased fracture risk. However, limited previous r weiter...
Author: Via JD, Daly RM, Owen PJ, Mundell NL, Rantalainen T, Fraser SF
Source: Bone, 2019; 127(): 367-375, PMID: 31189088
GID: 4926; Last update: 17.06.2019
Scientific Publications (2019)
Dietary inflammatory index® and cortical bone outcomes in healthy adolescent children.
Diet is thought to modulate inflammation. This study shows no relationships between the dietary inflammatory index (DII) and biomarkers of inflammation or bone after adjusting for covariates. Monocyte chemoattr weiter...
Author: Coheley LM, Shivappa N, Hebert JR, Lewis RD
Source: Osteoporos Int, 2019; 30(8): 1645-1654, PMID: 31143990
GID: 4912; Last update: 03.06.2019
Scientific Publications (2019)
Breech presentation is associated with lower adolescent tibial bone strength.
We compared bone outcomes in adolescents with breech and cephalic presentation. Tibia bone mineral content, density, periosteal circumference, and cross-sectional moment of inertia were lower in breech presenta weiter...
Author: Tobias JH, Sayers A, Deere KC, Heazell AEP, Lawlor DA, Ireland A
Source: Osteoporos Int, 2019; 30(7): 1423-1432, PMID: 31020365
GID: 4895; Last update: 26.04.2019
Scientific Publications (2019)
Long-term Outcomes of Adolescent Anorexia Nervosa on Bone.
PURPOSE: Anorexia nervosa (AN) is a chronic and life-threatening eating disorder that can have a considerable negative impact on the growing skeleton. We hypothesized that the long-term impact on bone health m weiter...
Author: Mumford J, Kohn M, Briody J, Miskovic-Wheatley J, Madden S, Clarke S, Biggin A, Schindeler A, Munns C
Source: J Adolesc Health, 2019; 64(3): 305-310, PMID: 30819332
GID: 4867; Last update: 04.03.2019
Scientific Publications (2018)
The Effectiveness of Physical Exercise on Bone Density in Osteoporotic Patients.
Physical exercise is considered an effective means to stimulate bone osteogenesis in osteoporotic patients. The authors reviewed the current literature to define the most appropriate features of exercise for in weiter...
Author: Benedetti MG, Furlini G, Zati A, Letizia Mauro G
Source: Biomed Res Int, 2018; 2018: 4840531, PMID: 30671455
GID: 4834; Last update: 01.02.2019
Scientific Publications (2019)
Seasonal Difference in Bone Characteristics and Body Composition of Elite Speed Skaters.
We investigated the changes in bone characteristics and body composition of elite speed skaters across two competitive seasons. Twelve elite speed skaters (age 23+/-4 years; height 1.73+/-0.09 m; body mass 68.5 weiter...
Author: Varley I, Greeves JP, Sale C
Source: Int J Sports Med, 2019; 40(1): 9-15, PMID: 30481829
GID: 4807; Last update: 03.12.2018
Scientific Publications (2018)
The loss of bone and muscle mass increases the risk of osteoporotic fractures. Dual energy X-ray absorptiometry (DXA) loses sensitivity in older age. The purpose of this study was to evaluate bone and muscle me weiter...
Author: Drey M, Henkel M, Petermeise S, Weiss S, Ferrari U, Rottenkolber M, Schmidmaier R
Source: J Clin Densitom, 2018; (): , PMID: 30425007
GID: 4803; Last update: 19.11.2018
Scientific Publications (2019)
Fracture risk assessment using dual-energy X-ray absorptiometry (DXA) frequently fails to diagnose osteoporosis amongst individuals who later experience fragility fractures. Hence, more reliable techniques tha weiter...
Author: Robinson DL, Jiang H, Song Q, Yates C, Lee PVS, Wark JD
Source: Biomech Model Mechanobiol, 2019; 18(1): 245-260, PMID: 30293203
GID: 4773; Last update: 15.10.2018
Scientific Publications (2018)
BACKGROUND: Australian adolescents with low motor competence (LMC) have higher fracture rates and poorer bone health compared to European normative data, but currently no normative data exists for Australians. weiter...
Author: Chivers P, Rantalainen T, McIntyre F, Hands B, Weeks B, Beck B, Sophia N, Hart N, Siafarikas A
Source: Res Dev Disabil, 2018; S0891-4222(18): 30179-3, PMID: 30119956
GID: 4738; Last update: 21.08.2018
Scientific Publications (2018)
Changes in bone microarchitecture following kidney transplantation - beyond bone mineral density.
Bone disease in kidney transplant recipients (KTRs) is characterised by bone mineral density (BMD) loss but bone microarchitecture changes are poorly defined. In this prospective cohort study, we evaluated bone weiter...
Author: Sharma AK, Toussaint ND, Elder GJ, Rajapakse CS, Holt SG, Baldock P, Robertson PL, Ebeling PR, Sorci OR, Masterson R
Source: Clin Transplant, 2018; 32(9): e13347, PMID: 29984421
GID: 4726; Last update: 16.07.2018
Scientific Publications (2018)
BACKGROUND: With the high prevalence of childhood obesity, especially among Hispanic children, understanding how body weight and its components of lean and fat mass affect bone development is important, given t weiter...
Author: Hetherington-Rauth M, Bea JW, Blew RM, Funk JL, Hingle MD, Lee VR, Roe DJ, Wheeler MD, Lohman TG, Going SB
Source: Bone, 2018; 113(): 144-150, PMID: 29800691
GID: 4695; Last update: 14.06.2018
Scientific Publications (2018)
We previously reported significant gains in pQCT measures of tibia trabecular bone mineral density (BMD) and cortical structure following completion of therapy in children and adolescents with acute lymphoblast weiter...
Author: Mostoufi-Moab S, Kelly A, Mitchell JA, Baker J, Zemel BS, Brodsky J, Long J, Leonard MB
Source: Bone, 2018; 112(): 128-135, PMID: 29679731
GID: 4676; Last update: 02.05.2018
Scientific Publications (2018)
DXA lean mass measurement for sarcopenia diagnosis is not always possible. Bioelectric impedance spectroscopy (BIS), a portable technology, is a potential alternative to DXA-measured lean mass. This pilot study weiter...
Author: Siglinsky E, Buehring B, Krueger D, Binkley N, Yamada Y
Source: Osteoporos Int, 2018; 29(7): 1653-1657, PMID: 29574521
GID: 4662; Last update: 13.04.2018
Scientific Publications (2018)
Physical activity, but not sedentary time, influences bone strength in late adolescence.
Physical activity is essential for optimal bone strength accrual, but we know little about interactions between physical activity, sedentary time, and bone outcomes in older adolescents. Physical activity (by a weiter...
Author: Tan VP, Macdonald HM, Gabel L, McKay HA
Source: Arch Osteoporos, 2018; 13(1): 31, PMID: 29556801
GID: 4653; Last update: 22.03.2018
Scientific Publications (2018)
Higher step count is associated with greater bone mass and strength in women but not in men.
In this cross-sectional study, peripheral bone traits were examined relative to total daily steps measured with pedometer. Higher number of steps was associated with greater bone values at the calcaneus and ti weiter...
Author: Tolonen S, Sievanen H, Hirvensalo M, Laaksonen M, Mikkila V, Palve K, Lehtimaki T, Raitakari O, Kahonen M
Source: Arch Osteoporos, 2018; 13(1): 20, PMID: 29511893
GID: 4646; Last update: 19.03.2018
Scientific Publications (2017)
[This corrects the article on p. 273 in vol. 41, PMID: 28503461., GID: 4447]. weiter...
Author: Park C, Park ES, Choi JY, Cho Y, Rha DW
Source: Ann Rehabil Med, 2017; 41(4): 722-723, PMID: 28971060
Keywords: Corrections for GID:4447
GID: 4590; Last update: 14.01.2018
More information: Original Article
Scientific Publications (2018)
Context: Patients with Turner Syndrome (TS) are at risk of osteoporotic fractures. Objective: The aims of this study were to assess the incidence of clinically significant fractures in girls with TS and prospec weiter...
Author: Soucek O, Schonau E, Lebl J, Willnecker J, Hlavka Z, Sumnik Z
Source: J Clin Endocrinol Metab 2018, 103(3):, 2018; 103(3): 1188–1197, PMID: 29300907
GID: 4571; Last update: 08.01.2018
Scientific Publications (2017)
The bone is one of the relevant target organs of heavy metals, and heavy metal toxicity is associated with several degenerative processes, such osteoporosis and bone mineral alterations, that could lead to frac weiter...
Author: Lavado-Garcia JM, Puerto-Parejo LM, Roncero-Martin R, Moran JM, Pedrera-Zamorano JD, Aliaga IJ, Leal-Hernandez O, Canal-Macias ML
Source: Int J Environ Res Public Health, 2017; 14(12): 924-933, PMID: 29168740
Keywords: heavy metals; food; dietary intake; bone health; women’s health; premenopause; bone mineral density
GID: 4567; Last update: 28.11.2017
Scientific Publications (2018)
Obese adolescents have increased fracture risk, but effects of alterations in adiposity on bone accrual and strength in obese adolescents are not understood. We evaluated 12-month changes in trabecular and cort weiter...
Author: Kelley JC, Stettler-Davis N, Leonard MB, Hill D, Wrotniak BH, Shults J, Stallings VA, Berkowitz R, Xanthopoulos MS, Prout-Parks E, Klieger SB, Zemel BS
Source: J Bone Miner Res, 2018; 33(1): 42–53, PMID: 28884881
GID: 4518; Last update: 18.09.2017
Scientific Publications (2017)
There are no longitudinal pQCT data of bone growth and development from sub-Saharan Africa, where rapid environmental, societal and economic transitions are occurring, and where fracture rates are predicted to weiter...
Author: Schoenbuchner SM, Pettifor JM, Norris SA, Micklesfield LK, Prentice A, Ward KA
Source: J Bone Miner Res, 2017; 32(12): 2355–2366, PMID: 28834567
GID: 4488; Last update: 01.09.2017
Scientific Publications (2018)
The objective of this study was to compare the test-retest precision error for peripheral quantitative computed tomography (pQCT)-derived marrow density and marrow area segmentation at the tibia using 3 softwar weiter...
Author: Gibbs JC, Brown ZM, Wong AK, Craven BC, Adachi JD, Giangregorio LM
Source: J Clin Densitom, 2018; 21(2): 269-280, PMID: 28359675
GID: 4409; Last update: 10.04.2017
Scientific Publications (2011)
Gait speed and survival in older adults.
CONTEXT: Survival estimates help individualize goals of care for geriatric patients, but life tables fail to account for the great variability in survival. Physical performance measures, such as gait speed, mi weiter...
Author: Studenski S, Perera S, Patel K, Rosano C, Faulkner K, Inzitari M, Brach J, Chandler J, Cawthon P, Connor EB, Nevitt M, Visser M, Kritchevsky S, Badinelli S, Harris T, Newman AB, Cauley J, Ferrucci L, Guralnik J
Source: JAMA, 2011; 305(1): 50-8, PMID: 21205966
Keywords: Gait Speed
GID: 4364; Last update: 12.02.2017
More information: Original Article
Scientific Publications (2018)
Lower peripheral quantitative computed tomography (pQCT)-derived leg muscle density has been associated with fragility fractures in postmenopausal women. Limb movement during image acquisition may result in mot weiter...
Author: Chan AC, Adachi JD, Papaioannou A, Wong AK
Source: J Clin Densitom, 2018; 21(1): 130-139, PMID: 28065423
GID: 4337; Last update: 11.01.2017
Scientific Publications (2014)
Hintergrund: Der Erhalt von neuromuskularen Funktionen und einer tragfahigen Knochenmasse bei alteren Menschen wird immer wichtiger, besonders bei alteren Frauen mit verminderter Knochendichte, die zu Sturzen weiter...
Author: N Stolzenberg
Source: Thesis, 2014;
GID: 3473; Last update: 13.02.2014
Scientific Publications (2010)
Osteoporosis in Men Chapter 52: Exercise programs for Pateints with osteoporosis
Author: Felsenberg D., Runge M.
Source: Osteoporosis in Men, 2010; 635-652
GID: 3308; Last update: 17.09.2013
Scientific Publications (2013)
The effects of whole-body vibration on muscle strength and power: a meta-analysis.
Exercise with whole-body vibration (WBV) is becoming popular as an alternative to conventional training or as supplementary training. However, despite increasing research efforts in this field, additive effects weiter...
Author: Osawa Y, Oguma Y, Ishii N
Source: J Musculoskelet Neuronal Interact, 2013; 13(3): 342-52, PMID: 23989260
Keywords: Metaanalysis
GID: 3306; Last update: 10.09.2013
More information: Original Article
Scientific Publications (2013)
Changes in body composition in triathletes during an Ironman race.
PURPOSE: Triathletes lose body mass during an Ironman triathlon. However, the associated body composition changes remain enigmatic. Thus, the purpose of this study was to investigate Ironman-induced changes in weiter...
Author: Mueller SM, Anliker E, Knechtle P, Knechtle B, Toigo M
Source: Eur J Appl Physiol, 2013; 113: 2343–2352, PMID: 23748466
Keywords: Dual-energy X-ray absorptiometry (DXA)
Peripheral quantitative computed tomography (pQCT)
Glycogen Dehydration
GID: 3247; Last update: 09.07.2013
Scientific Publications (2010)
OBJECTIVE: To determine the reliability of ground reaction force during a vertical jump. DESIGN AND SETTING: Two test sessions 48 hours apart in which subjects performed five maximal vertical jumps with their r weiter...
Author: Cordova ML, Armstrong CW
Source: J Athl Train, 2010; 31(4): 342-5, PMID: 16558421
GID: 2969; Last update: 03.06.2012
More information: Original Article
Scientific Publications (2012)
The dynamics of bone structure development during pubertal growth.
The pubertal growth spurt is a time of rapid changes in bone length, mass and structure, followed by the cessation of longitudinal growth. The two best studied anatomical areas in this respect are the metaphyse weiter...
Author: Rauch F
Source: J Musculoskelet Neuronal Interact, 2012; 12(1): 1-6, PMID: 22373945
GID: 2904; Last update: 07.03.2012
More information: Original Article
Scientific Publications (2011)
Das vorliegende Buch bietet einen umfassenden Überblick zum Thema Gesundheit, Gesundheitsmanagement und Gesundheitsförderung in Unternehmen. Aufgrund der steigenden Altersstruktur der Erwerbspersonen nehmen a weiter...
Author: Seitz D.
Source: ISBN 3639384326, 2011;
Keywords: Betriebliche Gesundheitsförderung
GID: 2779; Last update: 08.12.2011
Scientific Publications (2011)
Why bones bend but don"t break.
The musculoskeletal system is adept at dissipating potentially damaging energy that could accelerate fracture consequent to multiple loading cycles. Microstructural damage reduces bone"s residual properties, bu weiter...
Author: Burr DB
Source: J Musculoskelet Neuronal Interact, 2011; 11(4): 270-85, PMID: 22130136
GID: 2776; Last update: 06.12.2011
More information: Original Article
Scientific Publications (2011)
The purpose of this study was to investigate the effect of Juvenile Idiopathic Arthritis (JIA) on lower limb muscle activity during a countermovement jump (CMJ). Two groups of patient data were collected; 6 pat weiter...
Author: Dwyer KD; Kennedy MJ; Lamontagne M; Roth J
Source: Portuguese Journal of Sport Sciences, ISBS 2011, 2011; 11(2): 721-3
GID: 2754; Last update: 05.10.2011
More information: Original Article
Scientific Publications (2011)
What do we currently know from in vivo bone strain measurements in humans
Bone strains are the most important factors for osteogenic adaptive responses. During the past decades, scientists have been trying to describe the relationship between bone strain and bone osteogenic responses weiter...
Author: Yang PF, Brüggemann GP, Rittweger J
Source: J Musculoskelet Neuronal Interact., 2011; 11(1): 8-20, PMID: 21364270
GID: 2584; Last update: 05.03.2011
More information: Original Article
Scientific Publications (2010)
Effects of oxidation on the power of chemically skinned rat soleus fibres
Oxidation alters calcium sensitivity, and decreases maximum isometric force (Po) and shortening velocity (Vmax) of single muscle fibres. To examine the effect of oxidation on the curvature of the force-velocity weiter...
Author: Gilliver SF, Jones DA, Rittweger J, Degens H
Source: J Musculoskelet Neuronal Interact., 2010; 10(4): 267-73, PMID: 21116063
GID: 2485; Last update: 02.12.2010
More information: Original Article
Scientific Publications (1994)
Determinants of peak muscle power: effects of age and physical conditioning
The relationships between absolute peak muscle power (Wpeak), muscle cross sectional area (CSAtot, i.e. the sum of both thigh and calf CSA) and muscle high energy phosphate concentration (adenosine 5"-triphosph weiter...
Author: Ferretti G, Narici MV, Binzoni T, Gariod L, Le Bas JF, Reutenauer H, Cerretelli P
Source: Eur J Appl Physiol Occup Physiol., 1994; 68(2): 111-5, PMID: 8194538
GID: 2462; Last update: 28.10.2010
Scientific Publications (2010)
Differential effects of countermovement magnitude and volitional effort on vertical jumping
The importance of vertical jumping in sport and rehabilitative medicine is widely recognized. Despite the ample use of jump tests to assess neuromuscular function, the differential effects of muscular activatio weiter...
Author: Salles AS, Baltzopoulos V, Rittweger J
Source: Eur J Appl Physiol., 2010; 111(3: 441-8, PMID: 20882293
Keywords: Mechanography – Electromyography – Motor control – Jump strategy –
Neuromuscular testing
GID: 2418; Last update: 13.10.2010
Scientific Publications (2010)
Whole-body vibration (WBV) is receiving increasing interest as a therapeutic modality to improve neuromuscular performance or to increase bone mass or density. In order to help improve the quality of reports ab weiter...
Author: Rauch F, Sievanen H, Boonen S, Cardinale M, Degens H, Felsenberg D, Roth J, Schoenau E, Verschueren S, Rittweger J
Source: J Musculoskelet Neuronal Interact., 2010; 10(3): 193-8, PMID: 20811143
GID: 2392; Last update: 03.09.2010
More information: Original Article
Scientific Publications (2008)
Reliability of measures obtained during single and repeated countermovement jumps
PURPOSE: To establish the reliability of various measures obtained during single and repeated countermovement jump (CMJ) performance in an elite athlete population. METHODS: Two studies, each involving 15 elite weiter...
Author: Cormack SJ, Newton RU, McGuigan MR, Doyle TL
Source: Int J Sports Physiol Perform., 2008; 3(2): 131-44, PMID: 19208922
GID: 2121; Last update: 28.12.2009
More information: Original Article
Scientific Publications (2009)
Intersession Reliability of Vertical Jump Height
Introduction: The usefulness of measurements in research depends on the extent to which the researcher can rely on data as accurate and meaningful indicators of a behavior. In short, the measurements have to weiter...
Author: SØRENSEN H, IVERSEN K
Source: 14th annual Congress ECSS 2009, Oslo, Book of Abstracts, 2009;
GID: 2120; Last update: 25.12.2009
Scientific Publications (1998)
Author: Frost HM, Ferretti JL, Jee WS
Source: Calcif Tissue Int., 1998; 62(1): 1-7, PMID: 9405724
GID: 2079; Last update: 25.11.2009
Scientific Publications (1992)
Skeletal adaptations during growth
NASA: The authors examine the role of mechanical usage in skeletal development. Principle mechanisms of bone physiology include longitudinal bone growth; modeling drifts; micromodeling; remodeling by the basic weiter...
Author: Jee WS, Frost HM
Source: Triangle., 1992; 31(2/3): 77-88, PMID: 11539347
GID: 2078; Last update: 25.11.2009
Scientific Publications (1992)
The role of changes in mechanical usage set points in the pathogenesis of osteoporosis
Mechanical usage (MU) effects on modeling drifts and BMU-based remodeling affect bone mass in defined ways. Decreased MU stops additions of bone by modeling and increases removal of bone next to marrow by remod weiter...
Author: Frost HM
Source: J Bone Miner Res., 1992; 7(3): 253-61, PMID: 1585826
GID: 2077; Last update: 25.11.2009
Scientific Publications (2007)
Mechanical efficiency during repetitive vertical jumping
The purpose of this study was to compare mechanical efficiency between repeated static jumps (SJ), countermovement jumps (CMJ), drop jumps from 75% of maximum CMJ jump height (75DJ) and drop jumps from 125% of weiter...
Author: McCaulley GO, Cormie P, Cavill MJ, Nuzzo JL, Urbiztondo ZG, McBride JM
Source: Eur J Appl Physiol., 2007; 101(1): 115-23, PMID: 17530275
GID: 2055; Last update: 23.11.2009
Scientific Publications (2006)
Direct corticospinal pathways contribute to neuromuscular control of perturbed stance
The antigravity soleus muscle (Sol) is crucial for compensation of stance perturbation. A corticospinal contribution to the compensatory response of the Sol is under debate. The present study assessed spinal, c weiter...
Author: Taube W, Schubert M, Gruber M, Beck S, Faist M, Gollhofer A
Source: J Appl Physiol., 2006; 101(2): 420-9, PMID: 16601305
GID: 1999; Last update: 23.10.2009
More information: Original Article
Scientific Publications (1974)
Isometric contraction of the abductor digiti minimi muscle in man
Isometric contraction of the abductor digiti minimi muscle (ADM) has been studied in six normal subjects. Twitch contraction times of ADM ranged from 60 to 68 ms and twitch torque ranged from 2·33 to 6·24 x 1 weiter...
Author: Burke D, Skuse NF, Lethlean AK
Source: J Neurol Neurosurg Psychiatry., 1974; 37(7): 825-34, PMID: 4852602
GID: 1996; Last update: 23.10.2009
More information: Original Article
Scientific Publications (1970)
Contraction times and fibre types in intact human muscle
Twitches were recorded in situ in muscles of normal humans by small transducers connected to a needle in the tendon. The twitches were elicited by stimuli in the endplate zone, the force of the smallest twitche weiter...
Author: Buchthal F, Schmalbruch H.
Source: Acta Physiol Scand, 1970; 79(4): 435-52, PMID: 5472111
Keywords: Contraction Time, muscle function
GID: 1995; Last update: 23.10.2009
Scientific Publications (2009)
Enhanced Skeletal Parameters in Gymnasts Are Not Attributable to Self-Selection Bias
Author: Dowthwaite J, Gero N, Rosenbaum P, Scerpella T
Source: ASBMR, 2009;
GID: 1956; Last update: 24.09.2009
Scientific Publications (2009)
Whole-body vibration training is a method for muscle strengthening that is increasingly used in a variety of clinical situations. Key descriptors of vibration devices include the frequency, the amplitude, and t weiter...
Author: Rauch F
Source: Dev Med Child Neurol., 2009; 51 Suppl 4: 166-8, PMID: 19740225
GID: 1951; Last update: 23.09.2009
Scientific Publications (1992)
Biomechanical loading of Achilles tendon during normal locomotion
Direct in vivo Achilles tendon force measurements open up new possibilities for understanding the loading of the Achilles tendon during natural locomotion. This article describes how these human experiments can weiter...
Author: Komi PV, Fukashiro S, Järvinen M
Source: Clin Sports Med., 1992; 11(3): 521-31, PMID: 1638639
GID: 1879; Last update: 04.08.2009
Scientific Publications (1995)
In vivo Achilles tendon loading during jumping in humans
Elastic behaviour of the human tendomuscular system during jumping was investigated by determination of the in vivo Achilles tendon force. A buckle-type transducer was implanted under local anaesthesia around t weiter...
Author: Fukashiro S, Komi PV, Järvinen M, Miyashita M
Source: Eur J Appl Physiol Occup Physiol., 1995; 71(5): 453-8, PMID: 8565978
GID: 1877; Last update: 04.08.2009
Scientific Publications (2000)
In vivo measurement-based estimations of the human Achilles tendon moment arm
The aim of the present study was to estimate and compare in vivo measurement-based Achilles tendon moment arm lengths at rest and during isometric plantarflexion maximum voluntary contraction (MVC) using the ce weiter...
Author: Maganaris CN, Baltzopoulos V, Sargeant AJ
Source: Eur J Appl Physiol., 2000; 83(4 -5): 363-9, PMID: 11138576
Keywords: maximum internal forces on tibia
GID: 1876; Last update: 04.08.2009
Scientific Publications (0)
Vibrationstraining befreit von Beckenbodenschwäche
Dauer: 12 Wochen Studie: Geprüft wurde das Verfahren bei 90 Frauen mit Becknbodenschwäche in einer multizentrischen Studie nahm ein Drittel der Frauen zuerst an einem herkömmlichen Beckenbodentraining u weiter...
Author: Viereck V
GID: 1871; Last update: 30.07.2009
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Scientific Publications (2008)
BACKGROUND/AIMS: The present analyses intend to clarify if gender and puberty modify the relationship between bone development (modeling and remodeling) and fat mass at the forearm. METHODS: Data were collected weiter...
Author: Fricke O, Sumnik Z, Tutlewski B, Stabrey A, Remer T, Schoenau E
Source: Horm Res., 2008; 70(2): 105-11, PMID: 18547958
GID: 1857; Last update: 28.07.2009
Scientific Publications (2008)
Mechanical influences on bone development in children
This review focuses on methodological concepts in the evaluation of skeletal muscle function and on adaptation. It is now thought that the critical property of bone is strength rather than weight, and that cont weiter...
Author: Schoenau E, Fricke O
Source: Eur J Endocrinol., 2008; 159 Suppl 1: S27-31, PMID: 18787052
GID: 1856; Last update: 28.07.2009
More information: Original Article
Scientific Publications (2008)
BACKGROUND: Several reports give evidence that the perichondral ossificiation of bone tubes (modeling) strongly depends on muscular forces in children and adolescents. The present analyses intend to investigate weiter...
Author: Fricke O, Beccard R, Semler O, Land C, Stabrey A, Tutlewski B, Remer T, Schoenau E
Source: Horm Res., 2008; 70(5): 285-93, PMID: 18824867
GID: 1855; Last update: 28.07.2009
Scientific Publications (2003)
What is new in neuro-musculoskeletal interactions: Bye-bye, density?
Author: Rauch F
Source: J Musculoskelet Neuronal Interact., 2003; 3(3): 258-60, PMID: 15758350
GID: 1851; Last update: 27.07.2009
More information: Original Article
Scientific Publications (2003)
What is new in neuro-musculoskeletal interactions: On soups, hips and humeri
Author: Rittweger J, Rauch F
Source: J Musculoskelet Neuronal Interact., 2003; 3(1): 101-4, PMID: 15758372
GID: 1850; Last update: 27.07.2009
More information: Original Article
Scientific Publications (2002)
What is new in neuro-musculoskeletal interactions: Strain on Bones
Author: Rauch F, Rittweger J
Source: J Musculoskelet Neuronal Interact., 2002; 2(5): 489-92, PMID: 15758418
GID: 1849; Last update: 27.07.2009
More information: Original Article
Scientific Publications (2001)
What is new in neuro-musculoskeletal interactions: Research with impact
Author: Rauch F, Rittweger J
Source: J Musculoskelet Neuronal Interact., 2001; 1(4): 393-8, PMID: 15758490
GID: 1848; Last update: 27.07.2009
More information: Original Article
Scientific Publications (2007)
What is new in neuro-musculoskeletal interactions: mechanotransduction, microdamage and repair
Author: Rittweger J
Source: J Musculoskelet Neuronal Interact., 2007; 7(2): 191-3, PMID: 17627090
GID: 1847; Last update: 27.07.2009
More information: Original Article
Scientific Publications (2005)
Revival of bone strength: the bottom line
Author: Järvinen TL, Sievänen H, Jokihaara J, Einhorn TA
Source: J Bone Miner Res., 2005; 20(5): 717-20, PMID: 15824843
GID: 1730; Last update: 19.02.2009
Scientific Publications (2008)
Updates on improvement of human athletic performance: focus on world records in athletics
INTRODUCTION: Progression of world records (WRs) in athletics is a reliable mean to assess the potentiality of the human body, which also reflects how society has evolved over time and will continue to evolve. weiter...
Author: Lippi G, Banfi G, Favaloro EJ, Rittweger J, Maffulli N
Source: Br Med Bull., 2008; 87: 7-15, PMID: 18723588
GID: 1779; Last update: 06.02.2009
Scientific Publications (2008)
Ten years muscle-bone hypothesis: What have we learned so far? -Almost a Festschrift-
The importance of mechanical stimuli for bone is widely appreciated. Mechanostat theory proposes a negative feedback system to explain the adaptation of bone by homeostatic control of peak strains. However, no weiter...
Author: Rittweger J
Source: J Musculoskelet Neuronal Interact., 2008; 8(2): 174-8, PMID: 18622086
GID: 1650; Last update: 28.11.2008
More information: Original Article
Scientific Publications (1987)
Drop jumping. II. The influence of dropping height on the biomechanics of drop jumping
In the literature, athletes preparing for explosive activities are recommended to include drop jumping in their training programs. For the execution of drop jumps, different techniques and different dropping he weiter...
Author: Bobbert MF, Huijing PA, van Ingen Schenau GJ
Source: Med Sci Sports Exerc., 1987; 19(4): 339-46, PMID: 3657482
GID: 1648; Last update: 28.11.2008
Scientific Publications (2000)
The view that nonmechanical agents dominate control of osteoblasts and osteoclasts and thus postnatal changes in bone strength and mass (agent --> effector cells --> disease) is obsolete. Nonmechanical agents i weiter...
Author: Jee WS
Source: J Musculoskelet Neuronal Interact., 2000; 1(1): 11-3, PMID: 15758518
GID: 1644; Last update: 20.11.2008
More information: Original Article
Scientific Publications (2005)
The Utah Paradigm of Skeletal Physiology with its key component, the mechanostat hypothesis, suggest plausible explanations of some of the tissue-level changes occurring from combining selected non-mechanical a weiter...
Author: Jee WS, Tian XY
Source: J Musculoskelet Neuronal Interact., 2005; 5(2): 110-8, PMID: 15951626
GID: 1641; Last update: 20.11.2008
More information: Original Article
Scientific Publications (2001)
The Utah paradigm on animal models of skeletal disorders: quo vadis
Skeletal disorders that need effective studies in suitable animal models include "osteoporosis", arthroses and hard and soft tissue healing. For people doing or analyzing such studies this article provides a br weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2001; 1(3): 185-91, PMID: 15758492
GID: 1602; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2005)
Author: P.D. Delmas, N. Khaltaev, M. Arriagada, M.L. Brandi, J. Cannata, E. Lau,
R. Lederman, R. Lorenc, H. Minne, J. Morales-Torres, H. Morii,
P. Sambrook, T. Torralba, J. Zanchetta, J.Y. Reginster
Source: Musculoskelet Neuronal Interact, 2005; 5(2): 105-109
GID: 1585; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2005)
Musculoskeletal responses of 2-year-old Thoroughbred horses to early training. Conclusions
This paper summarises and presents in context the main findings of an extensive series of studies of early training lasting 13 weeks in which the tissue responses of 2-year-old Thoroughbred horses were assessed weiter...
Author: Firth EC, Rogers CW
Source: N Z Vet J., 2005; 53(6): 377-83, PMID: 16317437
GID: 1620; Last update: 19.11.2008
Scientific Publications (2001)
From Wolff"s law to the Utah paradigm: insights about bone physiology and its clinical applications
Efforts to understand our anatomy and physiology can involve four often overlapping phases. We study what occurs, then how, then ask why, and then seek clinical applications. In that regard, in 1960 views, bone weiter...
Author: Frost HM
Source: Anat Rec., 2001; 262(4): 398-419, PMID: 11275971
GID: 1609; Last update: 19.11.2008
Scientific Publications (2004)
Coming changes in accepted wisdom about "osteoporosis"
Here a voice from the past suggests 28 changes that will affect how people study, manage, classify and think about "osteoporoses" today. Those changes depend mainly on two things: (i) "Connecting the dots" betw weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2004; 4(1): 78-85, PMID: 15615080
GID: 1608; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2003)
Here an octogenarian voice from the past argues that the physiology of fascia, ligaments and tendons has strong and useful analogs in some general features of bone physiology, including the latter"s tissue-leve weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2003; 3(3): 201-9, PMID: 15758342
GID: 1607; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2003)
Perspective: genetic and hormonal roles in bone disorders: insights of an updated bone physiology
In 1997 Professor J. Gorski suggested endocrinology needed new paradigms (Endocrine News 1997; 22:4,12). "Connecting the dots" between diverse facts and ideas drawn from many lines of inquiry, plus accumulating weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2003; 3(2): 118-35, PMID: 15758352
GID: 1606; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2003)
On the strength-safety factor (SSF) for load-bearing skeletal organs
The strength of healthy postnatal mammalian load-bearing bones, growth plates, joints, fascia, ligaments and tendons exceeds the minimum strength needed to keep voluntary mechanical usage from breaking or ruptu weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2003; 3(2): 136-40, PMID: 15758353
GID: 1605; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2003)
The pathogenesis of osteogenesis imperfecta (OI) baffled physiologists and physicians for over a century. Most past efforts to explain it depended heavily on cell and molecular biology and on changes in the mat weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2003; 3(1): 1-7, PMID: 15758360
GID: 1604; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2001)
Why should many skeletal scientists and clinicians learn the Utah paradigm of skeletal physiology
Adding later facts and ideas to a universally accepted "1960 paradigm" of skeletal physiology led to the still-evolving "Utah paradigm". The ASBMR"s William Neuman award in 2001 to one of the latter paradigm"s weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2001; 2(2): 121-30, PMID: 15758459
GID: 1603; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2000)
Why the ISMNI and the Utah paradigm? Their role in skeletal and extraskeletal disorders
Besides bringing problems, aging can let the mind"s eye see more clearly than before, and it can let us express ourselves better. As age, experience and common sense examine today"s skeletal medicine and surger weiter...
Author: Frost HM
Source: J Musculoskelet Neuronal Interact., 2000; 1(1): 5-9, PMID: 15758517
GID: 1601; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2000)
In a 1960 paradigm of skeletal physiology, effector cells (chondroblasts, fibroblasts, osteoblasts, osteoclasts, etc.) regulated by nonmechanical agents wholly determined the architecture, strength, and health weiter...
Author: Frost HM
Source: J Bone Miner Metab., 2000; 18(6): 305-16, PMID: 11052462
GID: 1599; Last update: 19.11.2008
Scientific Publications (1967)
Variation in the density of the femoral diaphysis with age
1. A detailed study of density variations with age in cortical bone samples from different areas of the femoral diaphysis has been carried out. 2. Bone of relatively high density and, conversely, of low densit weiter...
Author: Atkinson PJ, Weatherell JA
Source: J Bone Joint Surg Br., 1967; 49(4): 781-8, PMID: 6073195
GID: 1590; Last update: 19.11.2008
Scientific Publications (2005)
Bone growth in length and width: the Yin and Yang of bone stability
Bone growth in length is primarily achieved through the action of chondrocytes in the proliferative and hypertrophic zones of the growth plate. Longitudinal growth is controlled by systemic, local paracrine and weiter...
Author: Rauch F
Source: J Musculoskelet Neuronal Interact., 2005; 5(3): 194-201, PMID: 16172510
GID: 1586; Last update: 19.11.2008
More information: Original Article
Scientific Publications (2007)
Author: Sievänen H, Kannus P, Järvinen TL
Source: PLoS Med., 2007; 4(3): e27, PMID: 17341126
GID: 1517; Last update: 09.09.2008
More information: Original Article
Scientific Publications (2008)
Human remains from peat bogs, called "bog bodies," have yielded valuable insights into human history because of their excellent preservation of soft tissue. On the other hand, the acidic environment of the peat weiter...
Author: Schilling AF, Kummer T, Marshall RP, Bauerochse A, Jopp E, Pueschel K, Amling M
Source: Am J Phys Anthropol., 2008; 135(4): 479-83, PMID: 18000892
GID: 1502; Last update: 09.09.2008
Scientific Publications (2007)
Relative strength of the tibia and fibula and locomotor behavior in hominoids
The fibula has rarely been considered in comparative morphological studies, probably due to its relatively minor role in carrying mechanical loads. However, some differences in morphology (and inferred function weiter...
Author: Marchi D
Source: J Hum Evol., 2007; 53(6): 647-55, PMID: 17675139
GID: 1331; Last update: 19.06.2008
Scientific Publications (1988)
Risk factors for falls among elderly persons living in the community
To study risk factors for falling, we conducted a one-year prospective investigation, using a sample of 336 persons at least 75 years of age who were living in the community. All subjects underwent detailed cli weiter...
Author: Tinetti ME, Speechley M, Ginter SF
Source: N Engl J Med., 1988; 319(26): 1701-7, PMID: 3205267
GID: 1288; Last update: 21.03.2008
Scientific Publications (2003)
Bone mineral density in chimpanzees, humans, and Japanese macaques
We performed a comparative study of bone mechanical properties in the radii of chimpanzees (Pan troglodytes), humans (Homo sapiens), and Japanese macaques (Macaca fuscata) using peripheral quantitative computed weiter...
Author: Kikuchi Y, Udono T, Hamada Y
Source: Primates., 2003; 44(2): 151-5, PMID: 12687479
GID: 1257; Last update: 06.03.2008
Scientific Publications (2006)
Measurement of bone density and bone strength with pQCT
Author: J. Willnecker
Source: Novel approaches towards primate toxicology, 2006; 13 - 19
GID: 1213; Last update: 05.03.2008
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Scientific Publications (2004)
The peak bone mass concept: is it still relevant
The peak bone mass concept implies that optimal skeletal development during childhood and adolescence will prevent fractures in late adulthood. This concept is based on the observation that areal bone density i weiter...
Author: Schönau E
Source: Pediatr Nephrol., 2004; 19(8): 825-31, PMID: 15197638
GID: 1138; Last update: 26.02.2008
Scientific Publications (2004)
From bone biology to bone analysis
Bone development is one of the key processes characterizing childhood and adolescence. Understanding this process is not only important for physicians treating pediatric bone disorders, but also for clinicians weiter...
Author: Schoenau E, Saggese G, Peter F, Baroncelli GI, Shaw NJ, Crabtree NJ, Zadik Z, Neu CM, Noordam C, Radetti G, Hochberg Z
Source: Horm Res., 2004; 61(6): 257-69, PMID: 14963367
GID: 1136; Last update: 26.02.2008
Scientific Publications (2002)
Noninvasive Analysis of Bone Mass, Structure, and Strength
Author: JL Ferretti, GR Cointry, RF Capozza
Source: Orthopaedic Issues in Osteoporosis CRC Press, 2002; 145 - 167
GID: 1081; Last update: 07.02.2008
Scientific Publications (2002)
Author: JL Ferretti, HM Frost
Source: CRC Press 2002 (202 - 217)
Orthopaedic Issues in Osteoporosis CRC Press, 2002; 202 - 217
GID: 1083; Last update: 07.02.2008
Scientific Publications (1998)
Quantitative Bestimmung der Knochenmasse: heutiger Stand und Fallstricke der Methoden
Author: P Schneider, C Reiners
Source: Med Welt (1998) 49: 157 - 163, 1998; 49: 157-163
GID: 1088; Last update: 07.02.2008
Scientific Publications (2002)
Author: Frost HM, Schneider P, Schneider R
Source: Dtsch Med Wochenschr., 2002; 127(48): 2570-4, PMID: 12457328
GID: 1091; Last update: 07.02.2008
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Scientific Publications (1998)
Peripheral Quantitative Computed Tomography
Author: P Schneider, C Reiners
Source: Bone Densitometry and Osteoporosis Springer, 1998; 349-363
GID: 1093; Last update: 07.02.2008
Scientific Publications (2006)
Can exercise prevent osteoporosis
Commonly used definitions of osteoporosis rely upon the measurement of bone mass or bone mineral density and regard the difference between osteopenia and osteoporosis as gradual. An alternative definition has b weiter...
Author: Rittweger J
Source: J Musculoskelet Neuronal Interact., 2006; 6(2): 162-6, PMID: 16849827
GID: 1071; Last update: 01.02.2008
More information: Original Article
Scientific Publications (1997)
New Noninvasive pQCT Devices to Determine Bone Structure
Author: G Tysarczyk-Niemeyer
Source: J Jpn Soc Bone Morphom, 1997; 7: 97-105
GID: 1000; Last update: 29.01.2008
Scientific Publications (2000)
The "muscle-bone unit" in children and adolescents: a 2000 overview
In former views hormones, calcium, vitamin D and other humoral and nonmechanical agents dominated control of postnatal bone strength (and "mass") in children and adolescents. However later evidence that led to weiter...
Author: Frost HM, Schönau E
Source: J Pediatr Endocrinol Metab., 2000; 13(6): 571-90, PMID: 10905381
GID: 1027; Last update: 29.01.2008
Scientific Publications (2006)
Author: Mell WD
Source: IBoat Report, 2006; 3.2: 4-40
GID: 994; Last update: 25.01.2008
Scientific Publications (1990)
Author: P.Schneider, W. Börner
Source: Osteoporosis, 1990; 59: 921-924
GID: 974; Last update: 24.01.2008
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Scientific Publications (2007)
CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts
Fusion of macrophages is an essential step in the differentiation of osteoclasts, which play a central role in the development and remodeling of bone. Osteoclasts are important mediators of bone loss, which lea weiter...
Author: Cui W, Cuartas E, Ke J, Zhang Q, Einarsson HB, Sedgwick JD, Li J, Vignery A
Source: Proc Natl Acad Sci U S A., 2007; 104(36): 14436-41, PMID: 17726108
GID: 959; Last update: 24.01.2008
Scientific Publications (1992)
(English) Between May 1990 and February 1991 we enrolled 212 patients of 410 referred to our clinic for bone mass evaluation according to different diagnosis or therapeutic procedures. These patients were divi weiter...
Author: P. Schneider, W. Börner, J. Rendl, C. Eilles, K. Schlißke, M. Scheubeck
Source: Z Orthop (1992) 130: 16-21, 1992; 130: 16-21
GID: 975; Last update: 24.01.2008
Scientific Publications (2002)
Source: Acta Orthop Scand, 2002; Suppl 303) 43:: 44 - 52
GID: 864; Last update: 22.01.2008
More information: Original Article
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Scientific Publications (2002)
Osteoporosis is a common multifactorial disorder of reduced bone mass. The disorder in its most common form is generalized, affecting the elderly, both sexes, and all racial groups. Multiple environmental facto weiter...
Author: Peacock M, Turner CH, Econs MJ, Foroud T
Source: Endocr Rev., 2002; 23(3): 303-26, PMID: 12050122
GID: 724; Last update: 15.01.2008
Scientific Publications (2002)
The primary findings and conclusions of the present series of studies can be summarised as follows: I Studies I and II demonstrated that long-term racquet sports training had increased bone mineral mass and weiter...
Author: Kontulainen S
Source: Disseration, 2002;
Keywords: Bone Training
GID: 671; Last update: 07.01.2008
More information: Original Article
Scientific Publications (2002)
Author: Schönau E, Rauch F,
Source: Hufeland-Preis Jury, 2002;
GID: 634; Last update: 04.01.2008
Scientific Publications (2004)
A 2003 update of bone physiology and Wolff"s Law for clinicians
By 1892, Julius Wolff and others realized that mechanical loads can affect bone architecture in living beings, but the mechanisms responsible for this effect were unknown, and it had no known clinical applicati weiter...
Author: Frost HM
Source: Angle Orthod., 2004; 74(1): 3-15, PMID: 15038485
GID: 587; Last update: 03.01.2008
More information: Original Article
Scientific Publications (2003)
Stellenwert verschiedener Trainingsprogramme in der Prävention der Osteoporose
Problemstellung: Älteren Frauen wird zur Prävention der Osteoporose geraten, körperlich aktiv zu sein. Ziel dieser Studie war es, die Effizienz heute prinzipiell empfohlener Trainingsprogramme zu vergleich weiter...
Author: Siegrist M, Lammel C, Zelger O, Jeschke D
Source: Lammel C, Siegrist M, Zelger O, Jeschke D, 2003; 54 (7/8): 40
GID: 579; Last update: 02.01.2008
Scientific Publications (2006)
Vibration exercise makes your muscles and bones stronger: fact or fiction
Vibration transmitted to the whole body or part of it has been extensively studied in relation to the risks to the health and safety of workers. These studies have highlighted the particular danger of lower-bac weiter...
Author: Cardinale M, Rittweger J
Source: J Br Menopause Soc., 2006; 12(1): 12-8, PMID: 16513017
GID: 572; Last update: 18.12.2007
Scientific Publications (1996)
Differential shock transmission response of the human body to impact severity and lower limb posture
The shocks imparted to the foot during locomotion may lead to joint-degenerative diseases and jeopardize the visual-vestibular functions. The body relies upon several mechanisms and structures that have unique weiter...
Author: Lafortune MA, Lake MJ, Hennig EM
Source: J Biomech, 1996; 29(12): 1531-7, PMID: 8945651
GID: 29; Last update: 16.12.2007
Scientific Publications (1998)
When four-legged animals want to move quickly they gallop -- a gait that was thought to have no equivalent in humans. But a new paper shows that skipping in humans is biomechanically similar to galloping. In bo weiter...
Author: Farley CT
Source: Nature., 1998; 394(6695): 721-3
GID: 94; Last update: 16.12.2007
Scientific Publications (1998)
Biomechanics of walking and running: center of mass movements to muscle action
Author: Farley CT, Ferris DP
Source: Exerc Sport Sci Rev., 1998; 26: 253-85, PMID: 9696992
GID: 79; Last update: 16.12.2007
More information: Original Article
Scientific Publications (2004)
Muscle mechanical advantage of human walking and running: implications for energy cost
Muscular forces generated during locomotion depend on an animal"s speed, gait, and size and underlie the energy demand to power locomotion. Changes in limb posture affect muscle forces by altering the mechanica weiter...
Author: Biewener AA, Farley CT, Roberts TJ, Temaner M
Source: J Appl Physiol., 2004; 97(6): 2266-74, PMID: 15258124
GID: 100; Last update: 16.12.2007
Scientific Publications (2005)
Minimizing center of mass vertical movement increases metabolic cost in walking
A human walker vaults up and over each stance limb like an inverted pendulum. This similarity suggests that the vertical motion of a walker"s center of mass reduces metabolic cost by providing a mechanism for p weiter...
Author: Ortega JD, Farley CT
Source: J Appl Physiol., 2005; 99(6): 2099-107, PMID: 16051716
GID: 99; Last update: 16.12.2007
Scientific Publications (1998)
Mechanism of leg stiffness adjustment for hopping on surfaces of different stiffnesses
When humans hop in place or run forward, leg stiffness is increased to offset reductions in surface stiffness, allowing the global kinematics and mechanics to remain the same on all surfaces. The purpose of the weiter...
Author: Farley CT, Houdijk HH, Van Strien C, Louie M
Source: J Appl Physiol., 1998; 85(3): 1044-55, PMID: 9729582
GID: 98; Last update: 16.12.2007
Scientific Publications (1997)
Mechanics of locomotion in lizards
Lizards bend their trunks laterally with each step of locomotion and, as a result, their locomotion appears to be fundamentally different from mammalian locomotion. The goal of the present study was to determin weiter...
Author: Farley CT, Ko TC
Source: J Exp Biol., 1997; 200(Pt 16): 2177-88, PMID: 9286099
GID: 97; Last update: 16.12.2007
Scientific Publications (1997)
Maximum speed and mechanical power output in lizards
The goal of the present study was to test the hypothesis that maximum running speed is limited by how much mechanical power the muscular system can produce. To test this hypothesis, two species of lizards, Cole weiter...
Author: Farley CT
Source: J Exp Biol., 1997; 200(Pt 16): 2189-95, PMID: 9286100
GID: 96; Last update: 16.12.2007
Scientific Publications (1997)
Low cost of locomotion in the banded Gecko: a test of the nocturnality hypothesis
This study tested the hypothesis that there has been an evolutionary increase in locomotor performance capacity at low temperature in nocturnal lizards. Nocturnal lizards are often active at low and suboptimal weiter...
Author: Autumn K, Farley CT, Emshwiller M, Full RJ
Source: Physiol Zool., 1997; 70(6): 660-9, PMID: 9361140
GID: 95; Last update: 16.12.2007
Scientific Publications (1999)
Leg stiffness primarily depends on ankle stiffness during human hopping
When humans hop in place or run forward, they adjust leg stiffness to accommodate changes in stride frequency or surface stiffness. The goal of the present study was to determine the mechanisms by which humans weiter...
Author: Farley CT, Morgenroth DC
Source: J Biomech., 1999; 32(3): 267-73, PMID: 10093026
GID: 93; Last update: 16.12.2007
Scientific Publications (1996)
Leg stiffness and stride frequency in human running
When humans and other mammals run, the body"s complex system of muscle, tendon and ligament springs behaves like a single linear spring ("leg spring"). A simple spring-mass model, consisting of a single linear weiter...
Author: Farley CT, González O
Source: J Biomech., 1996; 29(2): 181-6, PMID: 8849811
GID: 92; Last update: 16.12.2007
Scientific Publications (2007)
Individual limb work does not explain the greater metabolic cost of walking in elderly adults
Elderly adults consume more metabolic energy during walking than young adults. Our study tested the hypothesis that elderly adults consume more metabolic energy during walking than young adults because they per weiter...
Author: Ortega JD, Farley CT
Source: J Appl Physiol., 2007; 102(6): 2266-73, PMID: 17363623
GID: 90; Last update: 16.12.2007
Scientific Publications (2000)
How animals move: an integrative view
Recent advances in integrative studies of locomotion have revealed several general principles. Energy storage and exchange mechanisms discovered in walking and running bipeds apply to multilegged locomotion and weiter...
Author: Dickinson MH, Farley CT, Full RJ, Koehl MA, Kram R, Lehman S
Source: Science., 2000; 288(5463): 100-6, PMID: 10753108
GID: 85; Last update: 16.12.2007
Scientific Publications (1997)
Interaction of leg stiffness and surfaces stiffness during human hopping
When mammals run, the overall musculoskeletal system behaves as a single linear "leg spring". We used force platform and kinematic measurements to determine whether leg spring stiffness (k(leg)) is adjusted to weiter...
Author: Ferris DP, Farley CT
Source: J Appl Physiol., 1997; 82(1): 15-22; discussion 13, PMID: 9029193
GID: 91; Last update: 16.12.2007
Scientific Publications (2005)
Independent metabolic costs of supporting body weight and accelerating body mass during walking
The metabolic cost of walking is determined by many mechanical tasks, but the individual contribution of each task remains unclear. We hypothesized that the force generated to support body weight and the work p weiter...
Author: Grabowski A, Farley CT, Kram R
Source: J Appl Physiol., 2005; 98(2): 579-83, PMID: 15649878
GID: 89; Last update: 16.12.2007
Scientific Publications (2005)
During hopping in place and running, humans maintain similar center of mass dynamics by precisely adjusting leg mechanics to compensate for moderate changes in surface stiffness. We investigated the limits of t weiter...
Author: Moritz CT, Farley CT
Source: J Exp Biol., 2005; 208(Pt 5): 939-49, PMID: 15755892
GID: 88; Last update: 16.12.2007
Scientific Publications (2003)
Human hopping on damped surfaces: strategies for adjusting leg mechanics
Fast-moving legged animals bounce along the ground with spring-like legs and agilely traverse variable terrain. Previous research has shown that hopping and running humans maintain the same bouncing movement of weiter...
Author: Moritz CT, Farley CT
Source: Proc Biol Sci., 2003; 270(1525): 1741-6, PMID: 12965003
GID: 87; Last update: 16.12.2007
Scientific Publications (2006)
Human hoppers compensate for simultaneous changes in surface compression and damping
On a range of elastic and damped surfaces, human hoppers and runners adjust leg mechanics to maintain similar spring-like mechanics of the leg and surface combination. In a previous study of adaptations to damp weiter...
Author: Moritz CT, Farley CT
Source: J Biomech., 2006; 39(6): 1030-8, PMID: 16549093
GID: 86; Last update: 16.12.2007
Scientific Publications (1979)
Regulation of stiffness by skeletomotor reflexes
Since the early 1950s when Merton introduced his "follow-up serco hypothesis" of movement control, the dominant optinion has held that strech and unloading reflexes function to control the length of a muscle in weiter...
Author: Houk JC
Source: Annu Rev Physiol., 1979; 41: 99-114
GID: 84; Last update: 16.12.2007
More information: Original Article
Scientific Publications (1991)
Hopping frequency in humans: a test of how springs set stride frequency in bouncing gaits
The storage and recovery of elastic energy in muscle-tendon springs is important in running, hopping, trotting, and galloping. We hypothesized that animals select the stride frequency at which they behave most weiter...
Author: Farley CT, Blickhan R, Saito J, Taylor CR
Source: J Appl Physiol., 1991; 71(6): 2127-32, PMID: 1778902
GID: 83; Last update: 16.12.2007
Scientific Publications (1998)
Determinants of the center of mass trajectory in human walking and running
Walking is often modeled as an inverted pendulum system in which the center of mass vaults over the rigid stance limb. Running is modeled as a simple spring-mass system in which the center of mass bounces along weiter...
Author: Lee CR, Farley CT
Source: J Exp Biol., 1998; 201(Pt 21): 2935-44, PMID: 9866878
GID: 82; Last update: 16.12.2007
Scientific Publications (1992)
Energetics of walking and running: insights from simulated reduced-gravity experiments
On Earth, a person uses about one-half as much energy to walk a mile as to run a mile. On another planet with lower gravity, would walking still be more economical than running? When people carry weights while weiter...
Author: Farley CT, McMahon TA
Source: J Appl Physiol., 1992; 73(6): 2709-12, PMID: 1490989
GID: 81; Last update: 16.12.2007
Scientific Publications (2002)
Energetics and mechanics of human running on surfaces of different stiffnesses
Mammals use the elastic components in their legs (principally tendons, ligaments, and muscles) to run economically, while maintaining consistent support mechanics across various surfaces. To examine how leg sti weiter...
Author: Kerdok AE, Biewener AA, McMahon TA, Weyand PG, Herr HM
Source: J Appl Physiol., 2002; 92(2): 469-78, PMID: 11796653
GID: 80; Last update: 16.12.2007
Scientific Publications (2006)
Athletic footwear, leg stiffness, and running kinematics
CONTEXT: The leg acts as a linear spring during running and hopping and adapts to the stiffness of the surface, maintaining constant total stiffness of the leg-surface system. Introducing a substance (eg, footw weiter...
Author: Bishop M, Fiolkowski P, Conrad B, Brunt D, Horodyski M
Source: J Athl Train., 2006; 41(4): 387-92, PMID: 17273463
GID: 77; Last update: 16.12.2007
Scientific Publications (2004)
Walking involves a cyclic exchange of gravitational potential energy and kinetic energy of the center of mass. Our goal was to understand how the limbs of walking quadrupeds coordinate the vertical movements of weiter...
Author: Griffin TM, Main RP, Farley CT
Source: J Exp Biol., 2004; 207(Pt 20): 3545-58, PMID: 15339951
GID: 78; Last update: 16.12.2007
Scientific Publications (1991)
A mechanical trigger for the trot-gallop transition in horses
It is widely thought that animals switch gaits at speeds that minimize energetic cost. Horses naturally switched from a trot to a gallop at a speed where galloping required more energy than trotting, and thus, weiter...
Author: Farley CT, Taylor CR
Source: Science., 1991; 253(5017): 306-8, PMID: 1857965
GID: 76; Last update: 16.12.2007
Scientific Publications (2002)
What is new in neuro-musculoskeletal interactions: Neuromuscular Science
Author: Rittweger J, Rauch F
Source: J Musculoskelet Neuronal Interact., 2002; 2(2): 177-80, PMID: 15758468
Keywords: Mechanostat
GID: 356; Last update: 04.12.2007
More information: Original Article
Scientific Publications (2004)
Die Ergebnisse Berliner BedRest-Studie
Author: Felsenberg D
Source: Statement, 2004;
Keywords: BBR, Berlin BedRest Study, ESA, Galileo Space
GID: 311; Last update: 02.12.2007
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Scientific Publications (1997)
Author: Frost HM
Source: Bone., 1997; 20(3): 183-9, PMID: 9071467
Keywords: Mechanostat
GID: 288; Last update: 02.12.2007
Scientific Publications (1995)
Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group
BACKGROUND. Many risk factors for hip fractures have been suggested but have not been evaluated in a comprehensive prospective study. METHODS. We assessed potential risk factors, including bone mass, in 9516 wh weiter...
Author: Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, Cauley J, Black D, Vogt TM
Source: N Engl J Med., 1995; 332(12): 767-73, PMID: 7862179
GID: 52; Last update: 02.12.2007
Scientific Publications (1989)
Risk factors for recurrent nonsyncopal falls. A prospective study
Falls are a major threat to the health of older persons. We evaluated potential risk factors for falls in 325 community-dwelling persons aged 60 years or older who had fallen during the previous year, then foll weiter...
Author: Nevitt MC, Cummings SR, Kidd S, Black D
Source: JAMA., 1989; 261(18): 2663-8, PMID: 2709546
GID: 53; Last update: 02.12.2007
Scientific Publications (1997)
Defining osteopenias and osteoporoses: another view (with insights from a new paradigm)
This article suggests classifying "osteoporoses" by their biomechanical pathogenesis instead of by their severity or their accompanying medical conditions. (A) In a "true osteoporosis," bone fragility would inc weiter...
Author: Frost HM
Source: Bone., 1997; 20(5): 385-91, PMID: 9145234
Keywords: Mechanostat
GID: 289; Last update: 02.12.2007
Scientific Publications (2003)
High-frequency vibration training increases muscle power in postmenopausal women
OBJECTIVE: To test whether training on a high-frequency (28Hz) vibrating platform improves muscle power and bone characteristics in postmenopausal women. DESIGN: Randomized controlled trial with 6-month follow- weiter...
Author: Russo CR, Lauretani F, Bandinelli S, Bartali B, Cavazzini C, Guralnik JM, Ferrucci L
Source: Arch Phys Med Rehabil., 2003; 84(12): 1854-7, PMID: 14669194
GID: 274; Last update: 02.12.2007
Scientific Publications (1989)
Predictors of falls among elderly people. Results of two population-based studies
A study was performed to identify and rank risk factors for falling among populations of institutionalized (fallers, N = 79, nonfallers, N = 70) and noninstitutionalized (fallers, N = 34, nonfallers, N = 34) el weiter...
Author: Robbins AS, Rubenstein LZ, Josephson KR, Schulman BL, Osterweil D, Fine G
Source: Arch Intern Med., 1989; 149(7): 1628-33, PMID: 2742437
GID: 55; Last update: 02.12.2007
Scientific Publications (2003)
Die Muskeln als Determinate des erfolgreichen Alterns
Author: Runge M
Source: MedReport, 2003; 13: 12-13
GID: 254; Last update: 01.12.2007
Scientific Publications (2000)
Neue Erkenntnisse über den Zusammenhang zwischen Knochenstabilität und Muskelkraft
Author: Schiessl H, Willnecker J
Source: TraumaLinc, 2000; 1:
Keywords: Mechanostat, Muscle-Bone Unit
GID: 190; Last update: 01.12.2007
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Scientific Publications (1999)
Prevention of falls in the elderly trial (PROFET): a randomised controlled trial
BACKGROUND: Falls in elderly people are a common presenting complaint to accident and emergency departments. Current practice commonly focuses on the injury, with little systematic assessment of the underlying weiter...
Author: Close J, Ellis M, Hooper R, Glucksman E, Jackson S, Swift C
Source: Lancet., 1999; 353(9147): 93-7, PMID: 10023893
GID: 109; Last update: 01.12.2007
Scientific Publications (1998)
Running in the real world: adjusting leg stiffness for different surfaces
A running animal coordinates the actions of many muscles, tendons, and ligaments in its leg so that the overall leg behaves like a single mechanical spring during ground contact. Experimental observations have weiter...
Author: Ferris DP, Louie M, Farley CT
Source: Proc Biol Sci., 1998; 265(1400): 989-94, PMID: 9675909
GID: 105; Last update: 01.12.2007
Scientific Publications (2004)
Impact of muscle power and force on gait speed in disabled older men and women
BACKGROUND: The purpose of this study was to explore the relationship between muscle power output at different external resistances and performance of functional tasks. The authors hypothesized that power at 40 weiter...
Author: Cuoco A, Callahan DM, Sayers S, Frontera WR, Bean J, Fielding RA
Source: J Gerontol A Biol Sci Med Sci., 2004; 59(11): 1200-6, PMID: 15602076
GID: 108; Last update: 01.12.2007
Scientific Publications (1993)
Running springs: speed and animal size
Trotting and hopping animals use muscles, tendons and ligaments to store and return elastic energy as they bounce along the ground. We examine how the musculoskeletal spring system operates at different speeds weiter...
Author: Farley CT, Glasheen J, McMahon TA
Source: J Exp Biol., 1993; 185: 71-86, PMID: 8294853
GID: 106; Last update: 01.12.2007
Scientific Publications (2001)
Soleus H-reflex gain in humans walking and running under simulated reduced gravity
The Hoffmann (H-) reflex is an electrical analogue of the monosynaptic stretch reflex, elicited by bypassing the muscle spindle and directly stimulating the afferent nerve. Studying H-reflex modulation provides weiter...
Author: Ferris DP, Aagaard P, Simonsen EB, Farley CT, Dyhre-Poulsen P
Source: J Physiol., 2001; 530(Pt 1): 167-80, PMID: 11136869
GID: 107; Last update: 01.12.2007
Scientific Publications (1999)
Runners adjust leg stiffness for their first step on a new running surface
Human runners adjust the stiffness of their stance leg to accommodate surface stiffness during steady state running. This adjustment allows runners to maintain similar center of mass movement (e.g., ground cont weiter...
Author: Ferris DP, Liang K, Farley CT
Source: J Biomech., 1999; 32(8): 787-94, PMID: 10433420
GID: 104; Last update: 01.12.2007
Scientific Publications (2004)
Passive dynamics change leg mechanics for an unexpected surface during human hopping
Humans running and hopping maintain similar center-of-mass motions, despite large changes in surface stiffness and damping. The goal of this study was to determine the contributions of anticipation and reaction weiter...
Author: Moritz CT, Farley CT
Source: J Appl Physiol., 2004; 97(4): 1313-22, PMID: 15169748
GID: 103; Last update: 01.12.2007
Scientific Publications (2004)
Neuromuscular changes for hopping on a range of damped surfaces
Humans hopping and running on elastic and damped surfaces maintain similar center-of-mass dynamics by adjusting stance leg mechanics. We tested the hypothesis that the leg transitions from acting like an energy weiter...
Author: Moritz CT, Greene SM, Farley CT
Source: J Appl Physiol., 2004; 96(5): 1996-2004, PMID: 14688034
GID: 102; Last update: 01.12.2007
Scientific Publications (2006)
Neuromechanical adaptation to hopping with an elastic ankle-foot orthosis
When humans hop or run on different surfaces, they adjust their effective leg stiffness to offset changes in surface stiffness. As a result, the overall stiffness of the leg-surface series combination remains i weiter...
Author: Ferris DP, Bohra ZA, Lukos JR, Kinnaird CR
Source: J Appl Physiol., 2006; 100(1): 163-70, PMID: 16179395
GID: 101; Last update: 01.12.2007
Scientific Publications (1996)
OBJECTIVE: To evaluate the effects of two exercise approaches, Tai Chi (TC) and computerized balance training (BT), on specified primary outcomes (biomedical, functional, and psychosocial indicators of frailty) weiter...
Author: Wolf SL, Barnhart HX, Kutner NG, McNeely E, Coogler C, Xu T
Source: J Am Geriatr Soc., 1996; 44(5): 489-97, PMID: 8617895
GID: 54; Last update: 01.12.2007
Scientific Publications (2000)
Wie geht es weiter mit der Messung der Knochendichte
Author: Semler J
Source: Mobiles Leben, 2000; 7: 7-9
GID: 17; Last update: 24.11.2007
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